An amphipathic helical region of the N-terminal barrel of phospholipid transfer protein is critical for ABCA1-dependent cholesterol efflux. (Q34655812)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18287097%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

An amphipathic helical region of the N-terminal barrel of phospholipid transfer protein is critical for ABCA1-dependent cholesterol efflux (English)

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3 January 2020

4

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3 January 2020

author name string

John F Oram

1

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3 January 2020

Gertrud Wolfbauer

2

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3 January 2020

Chongren Tang

3

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3 January 2020

John J Albers

5

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3 January 2020

language of work or name

English

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publication date

19 February 2008

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3 January 2020

number of pages

9

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Journal of Biological Chemistry

inferred from page(s)

published in

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3 January 2020

volume

283

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3 January 2020

issue

17

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3 January 2020

page(s)

11541-11549

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Cholesterol accumulation is increased in macrophages of phospholipid transfer protein-deficient mice: normalization by dietary alpha-tocopherol supplementation

3 January 2020

cites work

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7 July 2018

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Janus kinase 2 modulates the lipid-removing but not protein-stabilizing interactions of amphipathic helices with ABCA1.

7 July 2018

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7 July 2018

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Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.

7 July 2018

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Phosphorylation and stabilization of ATP binding cassette transporter A1 by synthetic amphiphilic helical peptides

7 July 2018

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Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol

7 July 2018

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ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux.

7 July 2018

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Phospholipid Transfer Protein Interacts with and Stabilizes ATP-binding Cassette Transporter A1 and Enhances Cholesterol Efflux from Cells

7 July 2018

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Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly

7 July 2018

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Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene

7 July 2018

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ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions

7 July 2018

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ABCA1-deficient mice: insights into the role of monocyte lipid efflux in HDL formation and inflammation

7 July 2018

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The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions

7 July 2018

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A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

7 July 2018

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Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation

7 July 2018

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7 July 2018

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Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1.

7 July 2018

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Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

7 July 2018

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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

7 July 2018

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A hydrophobic cluster at the surface of the human plasma phospholipid transfer protein is critical for activity on high density lipoproteins

7 July 2018

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ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

7 July 2018

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7 July 2018

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Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels

7 July 2018

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Increased prebeta-high density lipoprotein, apolipoprotein AI, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes

7 July 2018

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Neutralization and transfer of lipopolysaccharide by phospholipid transfer protein

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Cholesterol efflux from macrophage foam cells is enhanced by active phospholipid transfer protein through generation of two types of acceptor particles

26 October 2018

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ABCA1-induced cell surface binding sites for ApoA-I.

26 October 2018

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Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression.

26 October 2018

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Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I.

26 October 2018

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The biotin-capture lipid affinity assay: a rapid method for determining lipid binding parameters for apolipoproteins.

26 October 2018

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Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis

26 October 2018

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Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway

26 October 2018

1 reference

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Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors

26 October 2018

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Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein

26 October 2018

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Phospholipid transfer protein is regulated by liver X receptors in vivo

26 October 2018

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Regulation of murine plasma phospholipid transfer protein activity and mRNA levels by lipopolysaccharide and high cholesterol diet.

26 October 2018

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Identification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesis

26 October 2018

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Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency

26 October 2018

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12 December 2020

Plasma phospholipid mass transfer rate: relationship to plasma phospholipid and cholesteryl ester transfer activities and lipid parameters

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12 December 2020

Limited proteolysis of high density lipoprotein abolishes its interaction with cell-surface binding sites that promote cholesterol efflux

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12 December 2020

Structure and phospholipid transfer activity of human PLTP: analysis by molecular modeling and site-directed mutagenesis

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Phospholipid transfer protein enhances removal of cellular cholesterol and phospholipids by high-density lipoprotein apolipoproteins

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Absence of endogenous phospholipid transfer protein impairs ABCA1-dependent efflux of cholesterol from macrophage foam cells

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12 December 2020

Macrophage phospholipid transfer protein deficiency and ApoE secretion: impact on mouse plasma cholesterol levels and atherosclerosis

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Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol

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Human plasma phospholipid transfer protein causes high density lipoprotein conversion

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Identifiers

DOI

10.1074/JBC.M800117200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18287097%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18287097%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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