PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice. (Q34650321)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698938%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice (English)

1 reference

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21 January 2020

0 references

10

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21 January 2020

9

Lennart Mucke

1 reference

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21 January 2020

author name string

Doo-Sup Choi

1

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21 January 2020

Dan Wang

2

1 reference

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21 January 2020

Gui-Qui Yu

3

1 reference

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21 January 2020

Guofen Zhu

4

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21 January 2020

Viktor N Kharazia

5

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21 January 2020

J Peter Paredes

6

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21 January 2020

Wesley S Chang

7

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21 January 2020

Jason K Deitchman

8

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21 January 2020

language of work or name

English

0 references

publication date

12 May 2006

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

21 January 2020

published in

1 reference

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21 January 2020

volume

103

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21 January 2020

page(s)

8215-8220

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21 January 2020

issue

21

1 reference

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Clearance of Alzheimer's Abeta peptide: the many roads to perdition.

21 January 2020

cites work

1 reference

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Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein.

7 July 2018

1 reference

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Synthesis and degradation of endothelin-1.

7 July 2018

1 reference

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

7 July 2018

1 reference

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

7 July 2018

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Hydrogen peroxide regulation of bovine endothelin-converting enzyme-1.

7 July 2018

1 reference

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Transcriptional mechanism of protein kinase C-induced isoform-specific expression of the gene for endothelin-converting enzyme-1 in human endothelial cells

7 July 2018

1 reference

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Clearing the brain's amyloid cobwebs

7 July 2018

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Alzheimer's disease: genes, proteins, and therapy

7 July 2018

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Blockade of PKC epsilon activation attenuates phorbol ester-induced increase of alpha-secretase-derived secreted form of amyloid precursor protein

7 July 2018

1 reference

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Regulation of amyloid precursor protein (APP) secretion by protein kinase calpha in human ntera 2 neurons (NT2N).

7 July 2018

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High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

7 July 2018

1 reference

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Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development

7 July 2018

1 reference

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A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice

7 July 2018

1 reference

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Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

7 July 2018

1 reference

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Cellular distribution of endothelin-converting enzyme-1 in human tissues.

7 July 2018

1 reference

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Overexpression of growth-associated proteins in the neurons of adult transgenic mice

7 July 2018

1 reference

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Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

7 July 2018

1 reference

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Molecular pharmacology of endothelin converting enzymes

7 July 2018

1 reference

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Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha.

7 July 2018

1 reference

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A permanent human cell line (EA.hy926) preserves the characteristics of endothelin converting enzyme from primary human umbilical vein endothelial cells

7 July 2018

1 reference

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Conventional protein kinase C (PKC)-alpha and novel PKC epsilon, but not -delta, increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 fibroblasts

7 July 2018

1 reference

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Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.

7 July 2018

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Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

21 January 2018

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Endothelin-converting enzyme-1 is expressed in human cerebral cortex and protects against Alzheimer's disease

21 January 2018

1 reference

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Protein kinase C epsilon suppresses Abeta production and promotes activation of alpha-secretase.

21 January 2018

1 reference

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Endothelin converting enzyme-1-, endothelin-1-, and endothelin-3-like immunoreactivity in the rat brain.

21 January 2018

1 reference

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Ets-1 upregulates matrix metalloproteinase-1 expression through extracellular matrix adhesion in vascular endothelial cells

21 January 2018

1 reference

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Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

21 January 2018

1 reference

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Kinetics of amyloid beta-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays.

21 January 2018

1 reference

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Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.

21 January 2018

1 reference

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Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.

21 January 2018

1 reference

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Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice

26 October 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1073/PNAS.0509725103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698938%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

0 references

1 reference

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21 January 2020

1 reference