The role of osteopontin in breast cancer: clinical and experimental studies (Q34639848)

3 August 2017

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title

The role of osteopontin in breast cancer: clinical and experimental studies (English)

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3 August 2017

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2

Chambers AF

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3 August 2017

Tuck AB

1

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3 August 2017

publication date

1 October 2001

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Journal of Mammary Gland Biology and Neoplasia

3 August 2017

published in

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3 August 2017

volume

6

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3 August 2017

issue

4

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3 August 2017

page(s)

419-429

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Osteopontin: a versatile regulator of inflammation and biomineralization

3 August 2017

cites work

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12 December 2020

Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin

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12 December 2020

Osteopontin expression and distribution in human carcinomas.

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12 December 2020

Phosphorylation, glycosylation, and transglutaminase sites in bovine osteopontin

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12 December 2020

The identification of osteopontin as a metastasis-related gene product in a rodent mammary tumour model

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12 December 2020

Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration

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12 December 2020

Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene.

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12 December 2020

Osteopontin expression in a group of lymph node negative breast cancer patients

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12 December 2020

The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro

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12 December 2020

Isolation of and effector for metastasis-inducing DNAs from a human metastatic carcinoma cell line

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12 December 2020

Cross-linking of osteopontin by tissue transglutaminase increases its collagen binding properties

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12 December 2020

Osteopontin expression in mammary gland development and tumorigenesis

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12 December 2020

Cell migration promoted by a potent GRGDS-containing thrombin-cleavage fragment of osteopontin

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12 December 2020

Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro

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12 December 2020

Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells

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12 December 2020

Osteopontin is a ligand for the alpha4beta1 integrin

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12 December 2020

Prognostic value of CD44 variant expression in primary breast cancer

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12 December 2020

CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis

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12 December 2020

Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

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12 December 2020

CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells

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12 December 2020

Gains and losses of CD44 expression during breast carcinogenesis and tumour progression

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12 December 2020

Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin).

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12 December 2020

Receptor-ligand interaction between CD44 and osteopontin (Eta-1)

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12 December 2020

Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin-ligand interaction in kidney morphogenesis

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12 December 2020

Osteoprotegerin Is an αvβ3-induced, NF-κB-dependent Survival Factor for Endothelial Cells

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12 December 2020

A regulated interaction between alpha5beta1 integrin and osteopontin

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12 December 2020

Targeted inhibition of osteopontin expression in the mammary gland causes abnormal morphogenesis and lactation deficiency

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12 December 2020

Urokinase receptor interacts with alpha(v)beta5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer

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12 December 2020

Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice

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12 December 2020

Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase

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12 December 2020

Elevated expression of secreted phosphoprotein I (osteopontin, 2ar) as a consequence of neoplastic transformation.

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12 December 2020

Osteopontin(OPN)-induced increase in human mammary epithelial cell invasiveness is urokinase (uPA)-dependent

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12 December 2020

The LCC15-MB human breast cancer cell line expresses osteopontin and exhibits an invasive and metastatic phenotype

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12 December 2020

Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain

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12 December 2020

The role of osteopontin in tumorigenesis and metastasis.

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12 December 2020

The activation state of alphavbeta 3 regulates platelet and lymphocyte adhesion to intact and thrombin-cleaved osteopontin

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12 December 2020

Vascular endothelial growth factor and osteopontin in tumor biology

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12 December 2020

CD44 variant exon epitopes in primary breast cancer and length of survival

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12 December 2020

Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin

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12 December 2020

Isolation and characterization of two sialoproteins present only in bone calcified matrix

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12 December 2020

Recombinant GST-human osteopontin fusion protein is functional in RGD-dependent cell adhesion

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12 December 2020

Adherence to osteopontin via alphavbeta3 suppresses phorbol ester-mediated apoptosis in MCF-7 breast cancer cells that overexpress protein kinase C-alpha

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12 December 2020

Tumor progression and metastasis in murine D2 hyperplastic alveolar nodule mammary tumor cell lines

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12 December 2020

Overcoming obstacles to metastasis--defenses against host defenses: osteopontin (OPN) as a shield against attack by cytotoxic host cells

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12 December 2020

Glycoprotein CD44 expression and its association with survival in breast cancer

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12 December 2020

Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity

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12 December 2020

Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival

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12 December 2020

Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin

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12 December 2020

Osteopontin-induced, integrin-dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met)

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12 December 2020

Altered sialylation of osteopontin prevents its receptor-mediated binding on the surface of oncogenically transformed tsB77 cells

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12 December 2020

Differential expression of osteopontin, PC4, and CEC5, a novel mRNA species, during in vitro angiogenesis

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12 December 2020

Urokinase plasminogen activator system gene expression is increased in human breast carcinoma and its bone metastases--a comparison of normal breast tissue, non-invasive and invasive carcinoma and osseous metastases

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12 December 2020

Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification

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12 December 2020

Alphav integrins mediate adhesion and migration of breast carcinoma cell lines

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12 December 2020

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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12 December 2020

Osteopontin and p53 expression are associated with tumor progression in a case of synchronous, bilateral, invasive mammary carcinomas

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12 December 2020

Interaction between CD44 and osteopontin as a potential basis for metastasis formation

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12 December 2020

Tumor cells are the source of osteopontin and bone sialoprotein expression in human breast cancer.

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12 December 2020

Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo

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12 December 2020

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12 December 2020

Quantification of osteopontin in human plasma with an ELISA: basal levels in pre- and postmenopausal women

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12 December 2020

Mapping of the cryptic integrin-binding site in osteopontin suggests a new mechanism by which thrombin can regulate inflammation and tissue repair

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12 December 2020

Osteopontin deficiency reduces experimental tumor cell metastasis to bone and soft tissues

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12 December 2020

Overexpression of protein kinase C-alpha in MCF-7 breast cancer cells results in differential regulation and expression of alphavbeta3 and alphavbeta5

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12 December 2020

Adhesion proteins in the biology of breast cancer: contribution of CD44.

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12 December 2020

Gene expression during involution of mammary gland (review).

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12 December 2020

Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer.

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12 December 2020

Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent.

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12 December 2020

NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival

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12 December 2020

Gene expression and phosphorylation of mouse osteopontin.

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12 December 2020

Posttranslational modifications of bovine osteopontin: identification of twenty-eight phosphorylation and three O-glycosylation sites

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12 December 2020

Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions

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12 December 2020

Osteopontin and beta 3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro

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12 December 2020

Osteopontin, a substrate for transglutaminase and Factor XIII activity

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12 December 2020

Introduction of antisense CD44S CDNA down-regulates expression of overall CD44 isoforms and inhibits tumor growth and metastasis in highly metastatic colon carcinoma cells

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12 December 2020

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

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12 December 2020

Depletion of alphaV integrins from osteosarcoma cells by intracellular antibody expression induces bone differentiation marker genes and suppresses gelatinase (MMP-2) synthesis.

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12 December 2020

Factor H binding to bone sialoprotein and osteopontin enables tumor cell evasion of complement-mediated attack

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12 December 2020

Expression of bone matrix protein messenger ribonucleic acids in human breast cancers. Possible involvement of osteopontin in development of calcifying foci

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12 December 2020

Phosphorylation of purified bovine bone sialoprotein and osteopontin by protein kinases

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12 December 2020

CD44 isoforms correlate with cellular differentiation but not with prognosis in human breast cancer

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12 December 2020

Tumor progression in four mammary epithelial cell lines derived from the same patient

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12 December 2020

Identification of the major phosphoprotein secreted by many rodent cell lines as 2ar/osteopontin: enhanced expression in H-ras-transformed 3T3 cells

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12 December 2020

The urokinase-type plasminogen activator system in cancer metastasis: A review

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12 December 2020

Calcitonin receptors, bone sialoprotein and osteopontin are expressed in primary breast cancers

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12 December 2020

Secondary structure predictions for rat osteopontin

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12 December 2020

Evidence for a role of osteopontin in macrophage infiltration in response to pathological stimuli in vivo

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12 December 2020

Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces.

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12 December 2020

CD44 modulates Hs578T human breast cancer cell adhesion, migration, and invasiveness

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12 December 2020

Identifiers

DOI

10.1023/A:1014734930781

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Dimensions Publication ID

3 August 2017

1031397175

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