Investigation of the DNA adducts formed in B6C3F1 mice treated with benzene: implications for molecular dosimetry (Q34637594)

3 August 2017

title

Investigation of the DNA adducts formed in B6C3F1 mice treated with benzene: implications for molecular dosimetry (English)

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3 August 2017

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W J Bodell

1

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3 August 2017

D N Pathak

2

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3 August 2017

G Lévay

3

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3 August 2017

Q Ye

4

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3 August 2017

K Pongracz

5

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3 August 2017

publication date

1 December 1996

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Environmental Health Perspectives

3 August 2017

published in

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3 August 2017

volume

104 Suppl 6

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3 August 2017

page(s)

1189-1193

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Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo.

3 August 2017

cites work

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Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells, mouse bone marrow macrophages and human bone marrow

7 July 2018

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A perspective on benzene leukemogenesis

7 July 2018

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7 July 2018

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Formation of muconaldehyde, an open-ring metabolite of benzene, in mouse liver microsomes: an additional pathway for toxic metabolites

7 July 2018

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Recent advances in the metabolism and toxicity of benzene

7 July 2018

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Metabolic activation of phenol by human myeloperoxidase and horseradish peroxidase

7 July 2018

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32P analysis of DNA adducts in tissues of benzene-treated rats

7 July 2018

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Benzene adducts with rat nucleic acids and proteins: dose-response relationship after treatment in vivo

7 July 2018

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Major sources of benzene exposure

7 July 2018

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DNA adduction by phenol, hydroquinone, or benzoquinone in vitro but not in vivo: nuclease P1-enhanced 32P-postlabeling of adducts as labeled nucleoside bisphosphates, dinucleotides and nucleoside monophosphates.

7 July 2018

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Detection of (3'-hydroxy)-3,N4-benzetheno-2'-deoxycytidine-3'-phosphate by 32P-postlabeling of DNA reacted with p-benzoquinone

7 July 2018

1 reference

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Detection of DNA adducts in HL-60 cells treated with hydroquinone and p-benzoquinone by 32P-postlabeling

7 July 2018

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Detection of 3'-hydroxy-1,N6-benzetheno-2'-deoxyadenosine 3'-phosphate by phosphorus-32 postlabeling of DNA reacted with p-benzoquinone

7 July 2018

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Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

7 July 2018

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Metabolism of hydroquinone by human myeloperoxidase: mechanisms of stimulation by other phenolic compounds

7 July 2018

1 reference

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Potentiation of DNA adduct formation in HL-60 cells by combinations of benzene metabolites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469766

Mechanism of the carcinogenic action of benzene: irreversible binding to rat liver DNA.

7 July 2018

1 reference

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Partial hepatectomy reduces both metabolism and toxicity of benzene

7 July 2018

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Benzene toxicity: a critical evaluation: hematotoxicity in humans

7 July 2018

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Synthesis of N2-(4-hydroxyphenyl)-2'-deoxyguanosine 3'-phosphate: comparison by 32P-postlabeling with the DNA adduct formed in HL-60 cells treated with hydroquinone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469766

DNA adduct formation in the bone marrow of B6C3F1 mice treated with benzene

26 October 2018

1 reference

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Effect of exposure concentration, exposure rate, and route of administration on metabolism of benzene by F344 rats and B6C3F1 mice

26 October 2018

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12 December 2020

Prostaglandin H synthase catalyzed oxidation of hydroquinone to a sulfhydryl-binding and DNA-damaging metabolite

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12 December 2020

Comparison of protein adducts of benzene oxide and benzoquinone in the blood and bone marrow of rats and mice exposed to [14C/13C6]benzene

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12 December 2020

Lack of DNA adduct formation in mice treated with benzene

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12 December 2020

Effects of toluene on the metabolism, disposition and hemopoietic toxicity of [3H]benzene

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12 December 2020

Benzene disposition in the rat after exposure by inhalation

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12 December 2020

Relationship between benzene toxicity and the disposition of 14C-labelled benzene metabolites in the rat

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12 December 2020

In vivo and in vitro binding of benzene to nucleic acids and proteins of various rat and mouse organs

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12 December 2020

Oxidation of catechol by horseradish peroxidase and human leukocyte peroxidase: reactions of o-benzoquinone and o-benzosemiquinone

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12 December 2020

An in vivo study of benzene metabolite DNA adduct formation in liver of male New Zealand rabbits

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12 December 2020

Identifiers

DOI

10.1289/EHP.961041189

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3 August 2017

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3 August 2017

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