Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease (Q34632017)

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English	Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease	scientific article

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scholarly article

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Europe PubMed Central

3 August 2017

Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease (English)

1 reference

Europe PubMed Central

3 August 2017

Alzheimer's disease

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ginsenoside Rg1

1 reference

ChEBI release 2020-05-28

author name string

QianKun Quan

1

1 reference

Europe PubMed Central

3 August 2017

Jue Wang

2

1 reference

Europe PubMed Central

3 August 2017

Xi Li

3

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Europe PubMed Central

3 August 2017

Yi Wang

4

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Europe PubMed Central

3 August 2017

language of work or name

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publication date

8 March 2013

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Europe PubMed Central

3 August 2017

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Europe PubMed Central

3 August 2017

8

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Europe PubMed Central

3 August 2017

3

1 reference

Europe PubMed Central

3 August 2017

e59155

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 March 2013

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3592813/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592813

7 July 2018

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1 reference

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Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease

1 reference

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ACP Journal Club. In older patients, rosiglitazone was associated with increased risk for stroke, heart failure, and mortality compared with pioglitazone

1 reference

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Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation

1 reference

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Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology

1 reference

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PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons

1 reference

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Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease

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Clearing amyloid through the blood-brain barrier

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Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

1 reference

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7 July 2018

Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta ); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity

1 reference

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Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

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1 reference

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Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice

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Insulin-degrading enzyme: embarking on amyloid destruction.

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Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity.

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21 January 2018

The study of ginsenoside on PPARgamma expression of mononuclear macrophage in type 2 diabetes

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Effects of ginsenosides on maze performance and brain choline acetyltransferase activity in scopolamine-treated young rats and aged rats.

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Fasting insulin and incident dementia in an elderly population of Japanese-American men.

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Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease.

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21 January 2018

Insulin increases CSF Abeta42 levels in normal older adults

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21 January 2018

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21 January 2018

Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.

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21 January 2018

Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0059155

21 January 2018

Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type.

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Telmisartan, a dual ARB/partial PPAR-γ agonist, protects myocardium from ischaemic reperfusion injury in experimental diabetes

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21 January 2018

Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance

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12 December 2020

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Ginsenoside Rg1 protects primary cultured rat hippocampal neurons from cell apoptosis induced by β-amyloid protein

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The plasmin system is induced by and degrades amyloid-beta aggregates

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https://pubmed.ncbi.nlm.nih.gov/23520555

12 December 2020

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Plasmin cleavage of the amyloid beta-protein: alteration of secondary structure and stimulation of tissue plasminogen activator activity

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10.1371/JOURNAL.PONE.0059155

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...859155Q

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1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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