Computational psychiatry. (Q34630298)

3 August 2017

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title

Computational psychiatry. (English)

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3 August 2017

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2

John H Krystal

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3 August 2017

Xiao-Jing Wang

1

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3 August 2017

language of work or name

English

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publication date

5 November 2014

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3 August 2017

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3 August 2017

volume

84

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3 August 2017

issue

3

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3 August 2017

page(s)

638-654

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Computational psychiatry: the brain as a phantastic organ

3 August 2017

cites work

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7 July 2018

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Insights into human behavior from lesions to the prefrontal cortex

7 July 2018

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Localized GABAergic inhibition of dendritic Ca(2+) signalling

7 July 2018

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Disorders of compulsivity: a common bias towards learning habits

7 July 2018

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Altered global brain signal in schizophrenia

7 July 2018

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The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry

7 July 2018

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Psychiatric disorders: diagnosis to therapy

7 July 2018

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Interneuron cell types are fit to function

7 July 2018

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Connectivity, pharmacology, and computation: toward a mechanistic understanding of neural system dysfunction in schizophrenia

7 July 2018

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Dissecting psychiatric spectrum disorders by generative embedding

7 July 2018

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Fledgling pathoconnectomics of psychiatric disorders

7 July 2018

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Cortical high-density counterstream architectures

7 July 2018

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Goals and habits in the brain

7 July 2018

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Functional maturation of the executive system during adolescence

7 July 2018

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The basal ganglia's contributions to perceptual decision making

7 July 2018

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Characterizing thalamo-cortical disturbances in schizophrenia and bipolar illness

7 July 2018

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Mapping anhedonia onto reinforcement learning: a behavioural meta-analysis

7 July 2018

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The importance of mixed selectivity in complex cognitive tasks.

7 July 2018

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Decision making: from neuroscience to psychiatry

7 July 2018

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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

7 July 2018

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Linking microcircuit dysfunction to cognitive impairment: effects of disinhibition associated with schizophrenia in a cortical working memory model

7 July 2018

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Capturing the angel in "angel dust": twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humans

7 July 2018

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From distributed resources to limited slots in multiple-item working memory: a spiking network model with normalization

7 July 2018

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Speech graphs provide a quantitative measure of thought disorder in psychosis

7 July 2018

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Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD.

7 July 2018

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Mechanisms of gamma oscillations

7 July 2018

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Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

7 July 2018

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The impact of orbitofrontal dysfunction on cocaine addiction

7 July 2018

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Mechanisms underlying cortical activity during value-guided choice

7 July 2018

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7 July 2018

Computational psychiatry

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Cognition in schizophrenia: core psychological and neural mechanisms

7 July 2018

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Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

7 July 2018

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Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

7 July 2018

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Molecular mechanisms of fear learning and memory.

7 July 2018

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Working memory: theories, models, and controversies

7 July 2018

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The size and burden of mental disorders and other disorders of the brain in Europe 2010.

7 July 2018

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Sleep abnormalities in schizophrenia may suggest impaired trans-thalamic cortico-cortical communication: towards a dynamic model of the illness

7 July 2018

1 reference

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Same or different? A neural circuit mechanism of similarity-based pattern match decision making

7 July 2018

1 reference

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Model-based influences on humans' choices and striatal prediction errors

7 July 2018

1 reference

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From reinforcement learning models to psychiatric and neurological disorders

7 July 2018

1 reference

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Glutamate receptor subtypes mediating synaptic activation of prefrontal cortex neurons: relevance for schizophrenia

7 July 2018

1 reference

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Deficits in positive reinforcement learning and uncertainty-driven exploration are associated with distinct aspects of negative symptoms in schizophrenia.

7 July 2018

1 reference

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More is less: a disinhibited prefrontal cortex impairs cognitive flexibility

7 July 2018

1 reference

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A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia

7 July 2018

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7 July 2018

Rethinking schizophrenia

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Internal representation of task rules by recurrent dynamics: the importance of the diversity of neural responses

7 July 2018

1 reference

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Neurophysiological and Computational Principles of Cortical Rhythms in Cognition

7 July 2018

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Research domain criteria (RDoC): toward a new classification framework for research on mental disorders

7 July 2018

1 reference

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Continuing the search for the engram: examining the mechanism of fear memories

7 July 2018

1 reference

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Toward a neurobiology of delusions

7 July 2018

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Dynamic Network Connectivity: A new form of neuroplasticity

7 July 2018

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States versus rewards: dissociable neural prediction error signals underlying model-based and model-free reinforcement learning

7 July 2018

1 reference

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Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

7 July 2018

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Understanding the role of DISC1 in psychiatric disease and during normal development

7 July 2018

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Proactive inhibitory control and attractor dynamics in countermanding action: a spiking neural circuit model

7 July 2018

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Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex

7 July 2018

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Complex brain networks: graph theoretical analysis of structural and functional systems

7 July 2018

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Theoretical neuroscience rising

7 July 2018

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Decision making in recurrent neuronal circuits

7 July 2018

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Hierarchically organized behavior and its neural foundations: a reinforcement learning perspective

7 July 2018

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A specialized NMDA receptor function in layer 5 recurrent microcircuitry of the adult rat prefrontal cortex

7 July 2018

1 reference

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Critical role of the prefrontal cortex in the regulation of hippocampus-accumbens information flow

7 July 2018

1 reference

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Computational models of schizophrenia and dopamine modulation in the prefrontal cortex.

7 July 2018

1 reference

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Successful choice behavior is associated with distinct and coherent network states in anterior cingulate cortex

7 July 2018

1 reference

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Hierarchical coding for sequential task events in the monkey prefrontal cortex

7 July 2018

1 reference

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The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia

7 July 2018

1 reference

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Task set and prefrontal cortex

7 July 2018

1 reference

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A framework for studying the neurobiology of value-based decision making

7 July 2018

1 reference

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Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative

7 July 2018

1 reference

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Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

7 July 2018

1 reference

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The construct of attention in schizophrenia

7 July 2018

1 reference

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NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons

7 July 2018

1 reference

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Weber's law in decision making: integrating behavioral data in humans with a neurophysiological model

7 July 2018

1 reference

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Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions

7 July 2018

1 reference

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The neural basis of decision making.

7 July 2018

1 reference

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Blocking of conditioning to a cocaine-paired stimulus: testing the hypothesis that cocaine perpetually produces a signal of larger-than-expected reward

7 July 2018

1 reference

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Dynamic causal models of neural system dynamics:current state and future extensions.

7 July 2018

1 reference

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From cognitive to neural models of working memory

7 July 2018

1 reference

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Pathophysiologically based treatment interventions in schizophrenia

7 July 2018

1 reference

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Glutamate and schizophrenia: beyond the dopamine hypothesis

7 July 2018

1 reference

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A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia

7 July 2018

1 reference

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Making working memory work: a computational model of learning in the prefrontal cortex and basal ganglia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Inhibitory control by an integral feedback signal in prefrontal cortex: a model of discrimination between sequential stimuli.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Working memory impairments in schizophrenia: a meta-analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Cortical inhibitory neurons and schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Flexible control of mutual inhibition: a neural model of two-interval discrimination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Neural synchrony indexes disordered perception and cognition in schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

A neural circuit basis for spatial working memory

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

NEURONAL CIRCUITS OF THE NEOCORTEX

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Psychology and neurobiology of simple decisions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Division of labor among distinct subtypes of inhibitory neurons in a cortical microcircuit of working memory

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Converging Evidence of NMDA Receptor Hypofunction in the Pathophysiology of Schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

7 July 2018

Dynamic causal modelling

1 reference

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The endophenotype concept in psychiatry: etymology and strategic intentions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Probabilistic decision making by slow reverberation in cortical circuits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Response of neurons in the lateral intraparietal area during a combined visual discrimination reaction time task.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Synaptic reverberation underlying mnemonic persistent activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Single neurons in prefrontal cortex encode abstract rules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

An integrative theory of prefrontal cortex function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Dopamine D1/D5 receptor modulation of excitatory synaptic inputs to layer V prefrontal cortex neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Sense and the single neuron: probing the physiology of perception

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

A neural substrate of prediction and reward

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

A framework for mesencephalic dopamine systems based on predictive Hebbian learning

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Working memory dysfunction in schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Cellular basis of working memory

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Computational neuroscience

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Context, cortex, and dopamine: a connectionist approach to behavior and biology in schizophrenia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Schizophrenics show spatial working memory deficits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Optimizing working memory with heterogeneity of recurrent cortical excitation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

NMDA receptors subserve persistent neuronal firing during working memory in dorsolateral prefrontal cortex

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

The initial field trials of DSM-5: new blooms and old thorns.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Short-term plasticity explains irregular persistent activity in working memory tasks

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

NMDA antagonist ketamine reduces task selectivity in macaque dorsolateral prefrontal neurons and impairs performance of randomly interleaved prosaccades and antisaccades

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

From circuits to behavior: a bridge too far?

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

The economic cost of brain disorders in Europe

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Neuron number and size in prefrontal cortex of children with autism

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

A neurocomputational model for cocaine addiction.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Dissociable components of rule-guided behavior depend on distinct medial and prefrontal regions.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Stochastic dynamics as a principle of brain function.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Cannabinoid-mediated disinhibition and working memory: dynamical interplay of multiple feedback mechanisms in a continuous attractor model of prefrontal cortex.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Reconciling reinforcement learning models with behavioral extinction and renewal: implications for addiction, relapse, and problem gambling

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Cortico-basal ganglia circuit mechanism for a decision threshold in reaction time tasks

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

A biophysically based neural model of matching law behavior: melioration by stochastic synapses.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

A recurrent network mechanism of time integration in perceptual decisions.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Uncertainty-based competition between prefrontal and dorsolateral striatal systems for behavioral control

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Addiction as a computational process gone awry

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Robust spatial working memory through homeostatic synaptic scaling in heterogeneous cortical networks.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Synaptic mechanisms and network dynamics underlying spatial working memory in a cortical network model.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Dopamine-mediated stabilization of delay-period activity in a network model of prefrontal cortex

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Synaptic basis of cortical persistent activity: the importance of NMDA receptors to working memory.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

The structure of common mental disorders

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Goal-directed instrumental action: contingency and incentive learning and their cortical substrates

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255477

Bitopertin: the good news and bad news

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25442941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Recurrent excitation in neocortical circuits

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25442941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEURON.2014.10.018

1 reference

3 August 2017

1 reference

3 August 2017

1 reference