Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans (Q34628045)

3 August 2017

Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans (English)

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conserved hypothetical protein

3 August 2017

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conserved hypothetical protein

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ceramide glucosyltransferase

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Cryptococcus neoforman

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6

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Maurizio Del Poeta

series ordinal

7

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Talar B. Kechichian

series ordinal

2

object named as

Talar B Kechichian

1 reference

3 August 2017

Philipp C. Rittershaus

series ordinal

1

object named as

Philipp C Rittershaus

1 reference

3 August 2017

3

Jeremy C Allegood

1 reference

3 August 2017

4

Alfred H Merrill

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3 August 2017

5

Mirko Hennig

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3 August 2017

language of work or name

English

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publication date

1 June 2006

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Journal of Clinical Investigation

3 August 2017

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3 August 2017

116

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3 August 2017

1651-1659

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3 August 2017

6

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describes a project that uses

3 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1466548/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1

1 reference

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Role of sphingolipids in microbial pathogenesis

7 July 2018

1 reference

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Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence

7 July 2018

1 reference

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Sphingolipids in infectious diseases

7 July 2018

1 reference

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Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry

7 July 2018

1 reference

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Recently discovered functions of glucosylceramides in plants and fungi

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm

7 July 2018

1 reference

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Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages

7 July 2018

1 reference

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Intracellular parasitism of macrophages by Cryptococcus neoformans

7 July 2018

1 reference

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Characterization of cerebrosides from the thermally dimorphic mycopathogen Histoplasma capsulatum: expression of 2-hydroxy fatty N-acyl (E)-Delta(3)-unsaturation correlates with the yeast-mycelium phase transition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Characterization of monoclonal antibody MEST-2 specific to glucosylceramide of fungi and plants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Characterization of UDP-glucose:ceramide glucosyltransferases from different organisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Structure elucidation of sphingolipids from the mycopathogen Sporothrix schenckii: identification of novel glycosylinositol phosphorylceramides with core manalpha1-->6Ins linkage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Human antibodies against a purified glucosylceramide from Cryptococcus neoformans inhibit cell budding and fungal growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection

7 July 2018

1 reference

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Cryptococcus neoformans resides in an acidic phagolysosome of human macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

7 July 2018

1 reference

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Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide

7 July 2018

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 July 2018

1 reference

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Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence.

7 July 2018

1 reference

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Presence of glucosylceramide in yeast and its relation to alkali tolerance of yeast.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

A monoclonal antibody to glucosylceramide inhibits the growth of Fonsecaea pedrosoi and enhances the antifungal action of mouse macrophages.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Defensins from insects and plants interact with fungal glucosylceramides.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Pathogenesis of cerebral Cryptococcus neoformans infection after fungemia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Disruption of the glucosylceramide biosynthetic pathway in Aspergillus nidulans and Aspergillus fumigatus by inhibitors of UDP-Glc:ceramide glucosyltransferase strongly affects spore germination, cell cycle, and hyphal growth

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Characterization of glucosylceramides in Pseudallescheria boydii and their involvement in fungal differentiation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Glucosylceramide synthases, a gene family responsible for the biosynthesis of glucosphingolipids in animals, plants, and fungi.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Identification of active site residues in glucosylceramide synthase. A nucleotide-binding catalytic motif conserved with processive beta-glycosyltransferases

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Characterization of Sphingolipids from Mycopathogens: Factors Correlating with Expression of 2-Hydroxy Fatty Acyl (E)-Δ3-Unsaturation in Cerebrosides ofParacoccidioides brasiliensisandAspergillus fumigatus†

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466548

Structure determination of soybean and wheat glucosylceramides by tandem mass spectrometry

9 December 2018

1 reference

12 December 2020

Dimorphic expression of cerebrosides in the mycopathogen Sporothrix schenckii

1 reference

12 December 2020

Cryptococcus neoformans: intracellular or extracellular?

1 reference

12 December 2020

The critical role of CO2 in the morphogenesis of Coccidioides immitis in cell-free subcutaneous chambers

1 reference

12 December 2020

Cerebroside of the dimorphic human pathogen, Candida albicans

1 reference

12 December 2020

Structural determination of N-2'-hydroxyoctadecenoyl-1-O-beta-D-glucopyranosyl-9-methyl-4, 8-sphingadienine from species of Aspergillus

1 reference

12 December 2020

The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella australis. Producing organism, fermentation, isolation, and biological activity

1 reference

12 December 2020

Glycolipids from Paracoccidioides brasiliensis. Isolation of a galactofuranose-containing glycolipid reactive with sera of patients with paracoccidioidomycosis

1 reference

12 December 2020

Cryptococcus neoformans survive and replicate in human microglia

1 reference

12 December 2020

Isolation and possible composition of glucosylceramides from Paracoccidioides brasiliensis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI27890

1 reference

3 August 2017

1 reference

3 August 2017

1 reference