Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes (Q34627899)

3 August 2017

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title

Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes (English)

1 reference

3 August 2017

Paul F Hollenberg

1

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PubMed ID

11996009

3 August 2017

language of work or name

English

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publication date

1 February 2002

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3 August 2017

Drug Metabolism Reviews

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3 August 2017

34

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3 August 2017

1-2

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3 August 2017

17-35

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Death attributed to the toxic interaction of triazolam, amitriptyline and other psychotropic drugs

3 August 2017

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Oxygen activation by cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Substrate interaction with cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Selective inhibitory interactions of alkoxymethylenedioxybenzenes towards mono-oxygenase activity in rat-hepatic microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Mechanism-based inactivators as probes of cytochrome P450 structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Suicide substrates for the alanine racemase of Escherichia coli B

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

A genetic analysis of processes regulating cytochrome P4501A1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

In vitro binding and functional studies comparing the human CYP1A1 negative regulatory element with the orthologous sequences from rodent genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Partial characterization of the human CYP1A1 negatively acting transcription factor and mutational analysis of its cognate DNA recognition sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Phenobarbital induction of cytochrome P-450 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Regulation of cytochrome P450 (CYP) genes by nuclear receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Evidence for increased translational efficiency in the induction of P450IIE1 by solvents: analysis of P450IIE1 mRNA polyribosomal distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Induction of P4502E1 by acetone in isolated rabbit hepatocytes. Role of increased protein and mRNA synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Characterization of cytochrome P450 2E1 induction in a rat hepatoma FGC-4 cell model by ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Gut wall metabolism of verapamil in older people: effects of rifampicin-mediated enzyme induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Rifampin drastically reduces plasma concentrations and effects of oral midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

The role of the stimulation of ANDPH-cytochrome P-450 reductase activity in hepatic, microsomal mixed function oxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Inhibition and induction of cytochrome P450 and the clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Virtual kinetics: using statistical experimental design for rapid analysis of enzyme inhibitor mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Oxidation-reduction properties of rat liver cytochromes P-450 and NADPH-cytochrome P-450 reductase related to catalysis in reconstituted systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

The enzymic formation of methylenedioxyphenyl derivative exhibiting an isocyanide-like spectrum with reduced cytochrome P-450 in hepatic microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Nitrosoalkanes as Fe(II) ligands in the 455-nm-absorbing cytochrome P-450 complexes formed from nitroalkanes in reducing conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Acetone enhancement of microsomal aniline para-hydroxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

Allosteric behavior in cytochrome p450-dependent in vitro drug-drug interactions: a prospective based on conformational dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120001387

21 January 2018

Identifiers

DOI

10.1081/DMR-120001387

1 reference

3 August 2017

1 reference

PubMed ID

11996009