Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines (Q34623813)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

review article

1 reference

title

Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Rm Antonijoan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Mj Barbanoj

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

31 August 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

Journal of Asthma and Allergy

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

73-92

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

26 January 2020

copyright license

start time

1 August 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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7 July 2018

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A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval

7 July 2018

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Blood-brain barrier transport of H1-antagonist ebastine and its metabolite carebastine

7 July 2018

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7 July 2018

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7 July 2018

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Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes

7 July 2018

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Ebastine: an update of its use in allergic disorders

7 July 2018

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7 July 2018

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Cetirizine counter-regulates interleukin-8 release from human epithelial cells (A549)

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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N-Dealkylation and hydroxylation of ebastine by human liver cytochrome P450.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Towards the optimal antihistamine: studies with ebastine

7 July 2018

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Torsades de pointes with terfenadine ingestion

7 July 2018

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Treatment of allergic rhinitis: effect on occupation productivity and work force costs

7 July 2018

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The guinea pig model for assessing cardiotoxic proclivities of second generation antihistamines.

7 July 2018

1 reference

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The role of ketoconazole in the QTc interval prolonging effects of H1-antihistamines in a guinea-pig model of arrhythmogenicity

7 July 2018

1 reference

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Occupational injuries and medication use.

7 July 2018

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Double-blind multicentre comparative study of ebastine, terfenadine and placebo in the treatment of chronic idiopathic urticaria in adults.

7 July 2018

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7 July 2018

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Ebastine in context. Introduction.

7 July 2018

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Ebastine. a review of its pharmacological properties and clinical efficacy in the treatment of allergic disorders

7 July 2018

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Positron emission tomographic study of central histamine H1-receptor occupancy in human subjects treated with epinastine, a second-generation antihistamine.

7 July 2018

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Cardiac actions of antihistamines

7 July 2018

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Comparative analysis of the cardiotoxicity proclivities of second generation antihistamines in an experimental model predictive of adverse clinical ECG effects.

7 July 2018

1 reference

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Comparison of ebastine to cetirizine in seasonal allergic rhinitis in adults

7 July 2018

1 reference

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Terfenadine, astemizole, and ebastine produce QTc interval prolongation in an experimental model predictive of adverse clinical ECG effects.

7 July 2018

1 reference

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Acute and subchronic effects of the H1-histamine receptor antagonist ebastine in 10, 20 and 30 mg dose, and triprolidine 10 mg on car driving performance

7 July 2018

1 reference

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Diazepam effects on the performance of healthy subjects are not enhanced by treatment with the antihistamine ebastine

7 July 2018

1 reference

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Pharmacokinetics of the H1-receptor antagonist ebastine and its active metabolite carebastine in healthy subjects.

7 July 2018

1 reference

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Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

7 July 2018

1 reference

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Ebastine: the effect of a new antihistamine on psychomotor performance and autonomic responses in healthy subjects

7 July 2018

1 reference

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A double-blind placebo-controlled study of the efficacy and tolerability of ebastine against hayfever in general practice patients

7 July 2018

1 reference

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The role of antihistamines in atopic dermatitis

7 July 2018

1 reference

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Ebastine in perennial allergic rhinitis

7 July 2018

1 reference

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Dynamics of mast cells in the nasal mucosa of patients with allergic rhinitis and non-allergic controls: a biopsy study

7 July 2018

1 reference

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Lack of pharmacodynamic and pharmacokinetic interactions of the antihistamine ebastine with ethanol in healthy subjects

7 July 2018

1 reference

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Placebo controlled comparison of acute effects of ebastine and clemastine on performance and EEG

7 July 2018

1 reference

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The selective eosinophil chemotactic activity of histamine

7 July 2018

1 reference

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Ebastine increases IFN-gamma production in patients with persistent allergic rhinitis.

7 July 2018

1 reference

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26 October 2018

1 reference

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International Conference on Harmonisation; guidance on S7B Nonclinical Evaluation of the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals; availability. Notice.

26 October 2018

1 reference

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Effect of combined histamine H1 and H3 receptor blockade on cutaneous microvascular permeability elicited by compound 48/80.

26 October 2018

1 reference

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A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of ebastine (20 mg and 10 mg) to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis

26 October 2018

1 reference

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Efficacy and safety of ebastine 20 mg compared to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled study

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Pruritus-associated response mediated by cutaneous histamine H3 receptors

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

A study comparing the inhibitory effects of single and repeated oral doses of ebastine and fexofenadine against histamine-induced skin reactivity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Ebastine inhibits T cell migration, production of Th2‐type cytokines and proinflammatory cytokines

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Efficacy of ebastine in the control of nasal congestion associated with allergic rhinitis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

A double-blind, placebo-controlled study of the efficacy and safety of ebastine 20 mg once daily given with and without food in the treatment of seasonal allergic rhinitis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Efficacy of ebastine, cetirizine, and loratadine in histamine cutaneous challenges

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Comparison of five new antihistamines (H1-receptor antagonists) in patients with allergic rhinitis using nasal provocation studies and skin tests

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Co-administration of histamine H1 antagonist and oral anticoagulants

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Duration of the antihistaminic effect after discontinuation of ebastine

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

A novel cytochrome P450 enzyme responsible for the metabolism of ebastine in monkey small intestine.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Problems of heart rate correction in assessment of drug-induced QT interval prolongation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Role of protein kinase Calpha in signaling from the histamine H(1) receptor to the nucleus

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Treatment of mosquito bites with ebastine: a field trial.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Suppression of mammalian K+ channel family by ebastine.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Seasonal allergic rhinitis and antihistamine effects on children's learning.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Absorption, distribution, metabolism and excretion of [14C]ebastine after repeated oral administration in rats.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Absorption, distribution, metabolism and excretion of [14C]ebastine after a single administration in rats.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Incidence and toxicological aspects of drugs detected in 484 fatally injured drivers and pedestrians in Ontario

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Transport of diphenhydramine in the central nervous system.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048600

Suppression by azelastine hydrochloride of NF-kappa B activation involved in generation of cytokines and nitric oxide

26 October 2018

1 reference

12 December 2020

Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis. The Ebastine Study Group

1 reference

12 December 2020

Clinical studies of the efficacy and tolerability of ebastine 10 or 20 mg once daily in the treatment of seasonal allergic rhinitis in the US

1 reference

12 December 2020

Activity of ebastine (10 and 20 mg) and cetirizine at 24 hours of a steady state treatment in the skin of healthy volunteers

1 reference

12 December 2020

Ebastine fast-dissolving tablets versus regular tablets: acceptability and preference in patients with allergic rhinitis

1 reference

12 December 2020

Computer-assisted comparison of the structural and electronic dispositions of ebastine and terfenadine

1 reference

12 December 2020

Combined histamine H1 and H3 receptor blockade produces nasal decongestion in an experimental model of nasal congestion

1 reference

12 December 2020

Pharmacokinetics and electrocardiographic effect of ebastine in young versus elderly healthy subjects

1 reference

12 December 2020

Overview of allergic mechanisms. Ebastine has more than an antihistamine effect

1 reference

12 December 2020

Clinical efficacy of ebastine in the treatment and prevention of seasonal allergic rhinitis

1 reference

12 December 2020

H4 histamine receptor mediates optimal migration of mast cell precursors to CXCL12

1 reference

12 December 2020

Efficacy and tolerability comparison of ebastine 10 and 20mg with loratadine 10mg: a double-blind, randomised study in patients with perennial allergic rhinitis

1 reference

12 December 2020

Mast cell mediators prostaglandin-D2 and histamine activate human eosinophils

1 reference

12 December 2020

Acceptance survey of a fast dissolving tablet pharmaceutical formulation in allergic patients. Satisfaction and expectancies

1 reference

12 December 2020

Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes

1 reference

12 December 2020

Increase in epithelial mast cell numbers in the nasal mucosa of patients with perennial allergic rhinitis

1 reference

12 December 2020

Med-psych drug-drug interactions update

1 reference

12 December 2020

Mechanism of the cardiotoxic actions of terfenadine

1 reference

12 December 2020

Pharmacologic characterization of a novel histamine receptor on human eosinophils

1 reference

12 December 2020

Introduction to antihistamine agents and antergan derivative

1 reference

12 December 2020

Occurrence of torsade de pointes with use of astemizole

1 reference

12 December 2020

Identifiers

DOI

10.2147/JAA.S3108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21437146%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference