A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy (Q34618606)

3 August 2017

title

A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy (English)

1 reference

3 August 2017

1 reference

Jun Zhou

1

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3 August 2017

Zhengming Chen

2

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3 August 2017

Agnes Malysa

3

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3 August 2017

Xin Li

4

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3 August 2017

Paula Oliveira

5

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3 August 2017

Yingtao Zhang

6

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3 August 2017

Gerold Bepler

7

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3 August 2017

language of work or name

English

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publication date

4 March 2013

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3 August 2017

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3 August 2017

volume

8

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3 August 2017

issue

3

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3 August 2017

page(s)

e58091

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Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

4 March 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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RRM1-induced metastasis suppression through PTEN-regulated pathways

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ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases.

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7 July 2018

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7 July 2018

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Mechanism for ribonucleotide reductase inactivation by the anticancer drug gemcitabine

21 January 2018

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In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant

21 January 2018

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RRM1 modulated in vitro and in vivo efficacy of gemcitabine and platinum in non-small-cell lung cancer.

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AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

21 January 2018

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DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer.

21 January 2018

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Automated subcellular localization and quantification of protein expression in tissue microarrays.

21 January 2018

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UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

21 January 2018

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Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells

21 January 2018

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10.1371/JOURNAL.PONE.0058091

21 January 2018

Identifiers

DOI

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3 August 2017

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3 August 2017

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