Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC). (Q34617012)

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English	Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC).	scientific article

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1 November 2019

Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC) (English)

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1 November 2019

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Trudy F C Mackay

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Robert R H Anholt

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Robert R H Anholt

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Teresa Borrás

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Tatiana V Morozova

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Stefanie L Heinsohn

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Richard F Lyman

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1 February 2003

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1 November 2019

Modelling neurodegenerative diseases in Drosophila: a fruitful approach?

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7 July 2018

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

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7 July 2018

Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues

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7 July 2018

Cytochrome P450 1B1 gene mutations in Japanese patients with primary congenital glaucoma(1).

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7 July 2018

A Drosophila model of Parkinson's disease

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Neuropathy target esterase

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7 July 2018

Modulation of myocilin/TIGR expression in human trabecular meshwork.

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7 July 2018

Identification of a single ancestral CYP1B1 mutation in Slovak Gypsies (Roms) affected with primary congenital glaucoma

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7 July 2018

Prevalence of mutations in TIGR/Myocilin in patients with adult and juvenile primary open-angle glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

7 July 2018

Gene transfer to the human trabecular meshwork by anterior segment perfusion.

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7 July 2018

Mutations in CYP1B1, the gene for cytochrome P4501B1, are the predominant cause of primary congenital glaucoma in Saudi Arabia

1 reference

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7 July 2018

Identification of a new 'TIGR' mutation in a family with juvenile-onset primary open angle glaucoma.

1 reference

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7 July 2018

The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila.

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7 July 2018

Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin.

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7 July 2018

Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product

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7 July 2018

A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

7 July 2018

Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

7 July 2018

Identification of a gene that causes primary open angle glaucoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

7 July 2018

Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

7 July 2018

Number of people with glaucoma worldwide

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

7 July 2018

Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

7 July 2018

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

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7 July 2018

Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein.

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7 July 2018

Genetic Transformation of Drosophila with Transposable Element Vectors

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7 July 2018

Effects of elevated intraocular pressure on outflow facility and TIGR/MYOC expression in perfused human anterior segments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

26 October 2018

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

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26 October 2018

Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462450

26 October 2018

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.

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26 October 2018

Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells

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26 October 2018

Regulation of aquaporin-4 water channels by phorbol ester-dependent protein phosphorylation.

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26 October 2018

Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma

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26 October 2018

Analysis of P transposable element functions in drosophila

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/12618402

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inefficient processing of an olfactomedin-deficient myocilin mutant: potential physiological relevance to glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12618402

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine kinase inhibitors suppress prostaglandin F2alpha-induced phosphoinositide hydrolysis, Ca2+ elevation and contraction in iris sphincter smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12618402

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1 reference

https://pubmed.ncbi.nlm.nih.gov/12618402

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based on heuristic

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Identification of novel mutations causing familial primary congenital glaucoma in Indian pedigrees

1 reference

https://pubmed.ncbi.nlm.nih.gov/12618402

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based on heuristic

inferred from PubMed ID database lookup

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1 November 2019

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