The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease (Q34615400)

3 August 2017

title

The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease (English)

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3 August 2017

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Helga Rübsamen-Waigmann

5

object named as

Helga Rübsamen-Waigmann

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Axel Mogk

7

object named as

Axel Mogk

1 reference

3 August 2017

Janine Kirstein

1

1 reference

3 August 2017

Anja Hoffmann

2

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3 August 2017

Hauke Lilie

3

1 reference

3 August 2017

Ronny Schmidt

4

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3 August 2017

Helga Rübsamen-Waigmann

5

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3 August 2017

Heike Brötz-Oesterhelt

6

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3 August 2017

Kürşad Turgay

8

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3 August 2017

publication date

1 April 2009

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3 August 2017

published in

EMBO Molecular Medicine

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3 August 2017

volume

1

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3 August 2017

issue

1

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3 August 2017

page(s)

37-49

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Bleach activates a redox-regulated chaperone by oxidative protein unfolding

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Localization of general and regulatory proteolysis in Bacillus subtilis cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

A common mechanism of cellular death induced by bactericidal antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

The antibiotic resistome: the nexus of chemical and genetic diversity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Molecular chaperones and protein quality control

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Adaptor protein controlled oligomerization activates the AAA+ protein ClpC

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

ClpS is an essential component of the N-end rule pathway in Escherichia coli.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Dysregulation of bacterial proteolytic machinery by a new class of antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

A genetic selection for supercoiling mutants of Escherichia coli reveals proteins implicated in chromosome structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Molecular insights into aminoglycoside action and resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Antibacterial resistance worldwide: causes, challenges and responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Sculpting the proteome with AAA(+) proteases and disassembly machines.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

MurAA, catalysing the first committed step in peptidoglycan biosynthesis, is a target of Clp-dependent proteolysis in Bacillus subtilis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Proteolysis in Bacterial Regulatory Circuits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Regulation by proteolysis in bacterial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Proteomic approach to understanding antibiotic action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Trigger Factor and DnaK possess overlapping substrate pools and binding specificities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

MecA, an adaptor protein necessary for ClpC chaperone activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

AAA+ proteins and substrate recognition, it all depends on their partner in crime

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

ClpS, a substrate modulator of the ClpAP machine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Molecular chaperones in the cytosol: from nascent chain to folded protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Posttranslational quality control: folding, refolding, and degrading proteins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Chaperone rings in protein folding and degradation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Exploring the conformational properties of the sequence space between two proteins with different folds: an experimental study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

The structure of ClpP at 2.3 A resolution suggests a model for ATP-dependent proteolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Self-compartmentalizing proteases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

In vitro analysis of the bacterial protein export

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Misread protein creates membrane channels: an essential step in the bactericidal action of aminoglycosides

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Sequence and structure of Clp P, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378108

Trigger factor and DnaK cooperate in folding of newly synthesized proteins.

7 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

Trigger factor forms a protective shield for nascent polypeptides at the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

Communication between ClpX and ClpP during substrate processing and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

Loss-of-function mutations in yjbD result in ClpX- and ClpP-independent competence development of Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis

21 January 2018

1 reference

12 December 2020

GFP vectors for controlled expression and dual labelling of protein fusions in Bacillus subtilis

1 reference

12 December 2020

Medicinal chemistry optimization of acyldepsipeptides of the enopeptin class antibiotics.

1 reference

12 December 2020

Dynamics of trigger factor interaction with translating ribosomes

1 reference

12 December 2020

ClpA and ClpP remain associated during multiple rounds of ATP-dependent protein degradation by ClpAP protease

1 reference

12 December 2020

Regulation of the Escherichia coli sigma-dependent envelope stress response

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.200900002

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1002/EMMM.200900002

1 reference

3 August 2017

1 reference

3 August 2017

1 reference