RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis (Q34611758)

3 August 2017

RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis (English)

1 reference

3 August 2017

Isabelle Leclerc

3

0 references

Guy A. Rutter

series ordinal

4

object named as

Guy A Rutter

1 reference

3 August 2017

Gao Sun

1

1 reference

PubMed ID

21135058

3 August 2017

Richard Reynolds

series ordinal

2

1 reference

3 August 2017

6 December 2010

1 reference

Disease Models & Mechanisms

3 August 2017

10

1 reference

based on heuristic

inferred from page(s)

published in

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3 August 2017

4

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3 August 2017

2

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3 August 2017

193-202

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PubMed ID

21135058

describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3046091/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo

7 July 2018

1 reference

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Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo

7 July 2018

1 reference

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C. elegans STRADalpha and SAD cooperatively regulate neuronal polarity and synaptic organization

7 July 2018

1 reference

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Critical roles for the TSC-mTOR pathway in β-cell function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy

7 July 2018

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Critical role for hypothalamic mTOR activity in energy balance

7 July 2018

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Role of mTOR in physiology and pathology of the nervous system

7 July 2018

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LKB1/STRAD promotes axon initiation during neuronal polarization.

7 July 2018

1 reference

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LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons

7 July 2018

1 reference

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Neuronal polarity: from extracellular signals to intracellular mechanisms

7 July 2018

1 reference

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AMP-activated protein kinase regulates the assembly of epithelial tight junctions

7 July 2018

1 reference

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Tubulin and CRMP-2 complex is transported via Kinesin-1

7 July 2018

1 reference

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The role of insulin receptor substrate 2 in hypothalamic and beta cell function.

7 July 2018

1 reference

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Molecular motors and mechanisms of directional transport in neurons

7 July 2018

1 reference

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Mammalian SAD kinases are required for neuronal polarization

7 July 2018

1 reference

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Pelizaeus-Merzbacher disease: pathogenic mechanisms and insights into the roles of proteolipid protein 1 in the nervous system

7 July 2018

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Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

7 July 2018

1 reference

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

7 July 2018

1 reference

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Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

7 July 2018

1 reference

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

7 July 2018

1 reference

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

7 July 2018

1 reference

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Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex

7 July 2018

1 reference

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LKB1, a protein kinase regulating cell proliferation and polarity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Sequential loss of myelin proteins during Wallerian degeneration in the rat spinal cord

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Axon pathology in neurological disease: a neglected therapeutic target

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta

7 July 2018

1 reference

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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

The development of cell processes induced by tau protein requires phosphorylation of serine 262 and 356 in the repeat domain and is inhibited by phosphorylation in the proline-rich domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Experimental spinal cord injury: Wallerian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Markers of mouse macrophage development detected by monoclonal antibodies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

MR-pathologic comparisons of wallerian degeneration in spinal cord injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

The establishment of polarity by hippocampal neurons in culture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Organization of cytoskeletal elements and organelles preceding growth cone emergence from an identified neuron in situ

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-N-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Polarity-regulating kinase partitioning-defective 1/microtubule affinity-regulating kinase 2 negatively regulates development of dendrites on hippocampal neurons

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Progressive white matter pathology in the spinal cord of transgenic mice expressing mutant (P301L) human tau.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Centrosome localization determines neuronal polarity.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Gradual loss of myelin and formation of an astrocytic scar during Wallerian degeneration in the human spinal cord.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

EMK protein kinase-null mice: dwarfism and hypofertility associated with alterations in the somatotrope and prolactin pathways.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046091

Hyperinsulinism in mice with heterozygous loss of K(ATP) channels

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21135058

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/DMM.006833

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

21135058