The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes (Q34610233)

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English	The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes (English)

1 reference

Europe PubMed Central

3 August 2017

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based on heuristic

inferred from title

monoclonal antibody

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based on heuristic

inferred from title

object named as

Michael Rak

4

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9

object named as

Garnett Kelsoe

1 reference

Europe PubMed Central

3 August 2017

11

object named as

Barton F Haynes

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Europe PubMed Central

3 August 2017

Richard M Scearce

5

object named as

Richard M Scearce

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Europe PubMed Central

3 August 2017

1

object named as

S Munir Alam

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Europe PubMed Central

3 August 2017

Mildred McAdams

2

object named as

Mildred McAdams

1 reference

Europe PubMed Central

3 August 2017

Zenaido T Camacho

7

object named as

Zenaido T Camacho

1 reference

Europe PubMed Central

3 August 2017

author name string

David Boren

3

1 reference

Europe PubMed Central

3 August 2017

Feng Gao

6

1 reference

Europe PubMed Central

3 August 2017

Daniel Gewirth

8

1 reference

Europe PubMed Central

3 August 2017

Pojen Chen

10

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Europe PubMed Central

3 August 2017

language of work or name

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publication date

1 April 2007

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Europe PubMed Central

3 August 2017

Journal of Immunology

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Europe PubMed Central

3 August 2017

178

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Europe PubMed Central

3 August 2017

4424-4435

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Europe PubMed Central

3 August 2017

7

1 reference

Europe PubMed Central

3 August 2017

A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Distribution and three-dimensional structure of AIDS virus envelope spikes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Antibody polyspecificity and neutralization of HIV-1: a hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Long-term multiple-dose pharmacokinetics of human monoclonal antibodies (MAbs) against human immunodeficiency virus type 1 envelope gp120 (MAb 2G12) and gp41 (MAbs 4E10 and 2F5).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Identification and characterization of circulating human transitional B cells

1 reference

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7 July 2018

The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

1 reference

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7 July 2018

Autoantibodies, lupus and the science of sabotage

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The molecular basis of antiphospholipid syndrome

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7 July 2018

Predominant autoantibody production by early human B cell precursors

1 reference

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7 July 2018

Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion

1 reference

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7 July 2018

A systematic analysis of sequences of human antiphospholipid and anti-beta2-glycoprotein I antibodies: the importance of somatic mutations and certain sequence motifs

1 reference

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Molecular and genetic characterizations of five pathogenic and two non-pathogenic monoclonal antiphospholipid antibodies

1 reference

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7 July 2018

Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins

1 reference

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7 July 2018

A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

1 reference

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7 July 2018

Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies.

1 reference

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7 July 2018

Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development

1 reference

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Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4.

1 reference

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7 July 2018

Immunization with recombinant canarypox vectors expressing membrane-anchored glycoprotein 120 followed by glycoprotein 160 boosting fails to generate antibodies that neutralize R5 primary isolates of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Antibody regulation of B cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2262928

7 July 2018

Experimental design for analysis of complex kinetics using surface plasmon resonance

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7 July 2018

B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

1 reference

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The antigenic structure of the HIV gp120 envelope glycoprotein

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Human Ig heavy chain CDR3 regions in adult bone marrow pre-B cells display an adult phenotype of diversity: evidence for structural selection of DH amino acid sequences.

1 reference

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Antibodies to beta 2-glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus

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Analysis by surface plasmon resonance of the influence of valence on the ligand binding affinity and kinetics of an anti-carbohydrate antibody

1 reference

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Receptor editing: an approach by autoreactive B cells to escape tolerance

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Receptor editing in self-reactive bone marrow B cells

1 reference

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7 July 2018

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

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Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

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Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities.

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Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies

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Identifiers

10.4049/JIMMUNOL.178.7.4424

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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