Lithium long-term treatment in mood disorders: clinical and genetic predictors (Q34609171)

3 August 2017

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title

Lithium long-term treatment in mood disorders: clinical and genetic predictors (English)

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3 August 2017

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Alessandro Serretti

1

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publication date

1 January 2002

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3 August 2017

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3 August 2017

3

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3 August 2017

1

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3 August 2017

117-129

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Forty years of lithium treatment

3 August 2017

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

The impact of lithium prophylaxis on the course of bipolar disorder: a review of the research evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Does lithium treatment still work? Evidence of stable responses over three decades

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Long term treatment of bipolar disorder

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium and recurrence in a long-term follow-up of bipolar affective disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Unanswered questions, unknown future for one of our oldest medications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Current therapeutic profile of lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Psychosis as a predictor of response to lithium maintenance treatment in bipolar affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Sex differences in response to lithium treatment

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Prediction of response to stabilizing lithium treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Long-term outcome of lithium prophylaxis in bipolar disorder: a 5-year prospective study of 402 patients at a lithium clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium maintenance treatment of depression and mania in bipolar I and bipolar II disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Intracellular Lithium Concentration and Clinical Response

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Intracellular lithium and clinical response

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Letter: Red-blood-cell lithium index and long-term maintenance treatment

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Red-blood-cell levels and lithium toxicity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium ratio, phospholipids and the incidence of side effects.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

The new generation of antipsychotic drugs: how atypical are they?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Psychiatric symptoms and syndromes among adolescent children of parents with lithium-responsive or lithium-nonresponsive bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Outcomes on lithium treatment as a tool for genetic studies in affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

A family study of bipolar I disorder in adolescence. Early onset of symptoms linked to increased familial loading and lithium resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Molecular mechanisms underlying mood stabilization in manic-depressive illness: the phenotype challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Pharmacogenomics of psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Pharmacogenetics and the serotonin system: initial studies and future directions.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Anti-bipolar therapy: mechanism of action of lithium

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Signal transduction pathways. Molecular targets for lithium's actions

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Phospholipase C I and II brain isozymes: immunohistochemical localization in neuronal systems in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Studies of inositol phospholipid-specific phospholipase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Ziskind-Somerfeld Research Award 1993. Biochemical, behavioral, and clinical studies of the role of inositol in lithium treatment and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Neural and developmental actions of lithium: a unifying hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11.2: genomic structure and polymorphism screening in manic-depressive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium: a molecular transducer of mood-stabilization in the treatment of bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium and brain signal transduction systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

A molecular mechanism for the effect of lithium on development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Signalling pathways in the brain: cellular transduction of mood stabilisation in the treatment of manic-depressive illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium augments fos protoonocogene expression in PC12 pheochromocytoma cells: implications for therapeutic action of lithium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Phorbol ester regulates stimulatory and inhibitory pathways of the hormone-sensitive adenylate cyclase system in rat reticulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Effects of lithium on second messenger systems in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

The mechanisms of action of lithium. II. Effects on adenylate cyclase activity and beta-adrenergic receptor binding in normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

The Bcl-2 protein family: arbiters of cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Bcl-2 gene family in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Apoptosis: unmasking the executioner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium at 50: have the neuroprotective effects of this unique cation been overlooked?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Subgenual prefrontal cortex abnormalities in mood disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium attenuates p53 levels in human neuroblastoma SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium chloride induces the expression of tyrosine hydroxylase in hNT neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Calcium antagonists in mania: a double-blind study of verapamil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium stimulates glutamate "release" and inositol 1,4,5-trisphosphate accumulation via activation of the N-methyl-D-aspartate receptor in monkey and mouse cerebral cortex slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Excitatory amino acid receptors, second messengers and regulation of intracellular Ca2+ in mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

GABA and mood disorders: a brief review and hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Chronic pharmacological treatment with certain antidepressants alters the expression and DNA-binding activity of transcription factor AP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium ions enhance cysteine string protein gene expression in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

The effect of lithium on methamphetamine-induced regional Fos protein expression in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

A bimodal model of the mechanism of action of lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium and serotonin function: implications for the serotonin hypothesis of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

5-HT neuroendocrine responses during psychotropic drug treatment: an investigation of the effects of lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Biogenic Amine Metabolites in Cerebrospinal Fluid of Depressed and Manic Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in psychiatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Effects of chronic lithium treatment on serotonin binding sites in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

5-HT1B receptors: a novel target for lithium. Possible involvement in mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Regulation of central serotonin transporters by chronic lithium: an autoradiographic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Effects of a chronic lithium treatment on cortical serotonin uptake sites and 5-HT1A receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Studies on human blood platelets in affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Long-term effect of lithium on the uptake of 5-hydroxytryptamine by human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium treatment and serotoninergic function. Neuroendocrine and behavioral responses to intravenous tryptophan in affective disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Serotonin does not mediate the adrenal catecholamine-releasing effect of acute lithium administration in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium reduced synaptic transmission and increased neuronal excitability without altering endogenous serotonin, norepinephrine and dopamine in rat hippocampal slices in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

The mechanisms of action of lithium. I. Effects on serotoninergic and noradrenergic systems in normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium attenuates the activation-euphoria but not the psychosis induced by d-amphetamine in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Lithium and bupropion antagonise the phasic changes in locomotor activity caused by dopamine infused into the rat nucleus accumbens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Acute effects of lithium on dopaminergic responses: iontophoretic studies in the rat visual cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Effects of a chronic lithium treatment on central dopamine neurotransporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Ongoing lithium treatment prevents relapse after total sleep deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Regulation of striatal dopamine release through 5-HT1 and 5-HT2 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Serotonin inhibits acetylcholine release from rat striatum slices: evidence for a presynaptic receptor-mediated effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Modulation of central cholinergic activity by GABA and serotonin: PET studies with 11C-benztropine in primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Use of unlinked genetic markers to detect population stratification in association studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Serotonin transporter gene associated with lithium prophylaxis in mood disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Research diagnostic criteria: rationale and reliability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Pharmacogenomics to predict drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Genetic determinants of clozapine-induced agranulocytosis: recent results of HLA subtyping in a non-jewish caucasian sample.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Experimental annotation of the human genome using microarray technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Long-term lithium treatment causes serotonin receptor down-regulation via serotonergic presynapses in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

Serotonin-dopamine interaction and its relevance to schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.1.117

21 January 2018

Identifiers

DOI

10.1517/14622416.3.1.117

1 reference

3 August 2017

1 reference

PubMed ID

11966408