Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency (Q34599892)

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English	Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

Tetsuya Ito

1

1 reference

Europe PubMed Central

3 August 2017

Yutaka Sendai

2

1 reference

Europe PubMed Central

3 August 2017

Satoshi Yamazaki

3

1 reference

Europe PubMed Central

3 August 2017

Marie Seki-Soma

4

1 reference

Europe PubMed Central

3 August 2017

Kensuke Hirose

5

1 reference

Europe PubMed Central

3 August 2017

Motoo Watanabe

6

1 reference

Europe PubMed Central

3 August 2017

Kazuo Fukawa

7

1 reference

Europe PubMed Central

3 August 2017

Hiromitsu Nakauchi

8

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

1 December 2014

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

9

1 reference

Europe PubMed Central

3 August 2017

12

1 reference

Europe PubMed Central

3 August 2017

e113833

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Genetically engineered pig models for human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Transcriptional and histological analyses of the thymic developmental process in the fetal pig

1 reference

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7 July 2018

Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Genetically modified pig models for human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs

1 reference

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7 July 2018

New generation humanized mice for virus research: comparative aspects and future prospects

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7 July 2018

Completion of the swine genome will simplify the production of swine as a large animal biomedical model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Role of recombination activating genes in the generation of antigen receptor diversity and beyond

1 reference

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7 July 2018

Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Modeling HIV infection and therapies in humanized mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Generation of an inbred miniature pig model of retinitis pigmentosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

An efficient protocol for inducing pseudopregnancy using estradiol dipropionate and follicular development associated with changes in reproductive hormones after prostaglandin F2alpha treatment in pseudopregnant sows

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

The pig: a model for human infectious diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

The reconstituted 'humanized liver' in TK-NOG mice is mature and functional.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Effect of epigenetic regulation during swine embryogenesis and on cloning by nuclear transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Development of the neonatal B and T cell repertoire in swine: implications for comparative and veterinary immunology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

alpha1,3-Galactosyltransferase-gene knockout in cattle using a single targeting vector with loxP sequences and cre-expressing adenovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Production of piglets derived from in vitro-produced blastocysts fertilized and cultured in chemically defined media: effects of theophylline, adenosine, and cysteine during in vitro fertilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Hierarchical Phenotypic and Epigenetic Variation in Cloned Swine1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

N-terminal RAG1 frameshift mutations in Omenn's syndrome: internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role in vivo for the N-terminal domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Cloned pigs produced by nuclear transfer from adult somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Partial V(D)J recombination activity leads to Omenn syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

RAG mutations in human B cell-negative SCID.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Somatic generation of antibody diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

T-cell antigen receptor genes and T-cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

The V(D)J recombination activating gene, RAG-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

7 July 2018

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

An immunodeficiency disease with RAG mutations and granulomas

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Development of a human adaptive immune system in cord blood cell-transplanted mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Pig cloning by microinjection of fetal fibroblast nuclei.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Production of cloned pigs from in vitro systems.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

A porcine model of familial adenomatous polyposis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Effect of equine chorionic gonadotropin on weaning-to-first service interval and litter size of female swine

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Antibody repertoire development in fetal and neonatal piglets. XXII. λ Rearrangement precedes κ rearrangement during B-cell lymphogenesis in swine.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Incomplete methylation reprogramming in SCNT embryos.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Serial cloning of pigs by somatic cell nuclear transfer: restoration of phenotypic normality during serial cloning.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Depigmentation of skin and hair color in the somatic cell cloned pig.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Identical mutations in RAG1 or RAG2 genes leading to defective V(D)J recombinase activity can cause either T-B-severe combined immune deficiency or Omenn syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249935

26 October 2018

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113833

21 January 2018

Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rγnull mice is attributed to a lack of CD11c+B220+CD122+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetics by DNA methylation for development of normal and cloned animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Il2rg gene-targeted severe combined immunodeficiency pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAG1/2 knockout pigs with severe combined immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/25437445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0113833

1 reference

Europe PubMed Central

3 August 2017

2014PLoSO...9k3833I

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1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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