A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice (Q34598657)

3 August 2017

title

A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice (English)

1 reference

3 August 2017

0 references

1 reference

Akane Ishihara

1

1 reference

3 August 2017

Akio Kanatani

2

1 reference

3 August 2017

Satoshi Mashiko

3

1 reference

3 August 2017

Takeshi Tanaka

4

1 reference

3 August 2017

Masayasu Hidaka

5

1 reference

3 August 2017

Akira Gomori

6

1 reference

3 August 2017

Hisashi Iwaasa

7

1 reference

3 August 2017

Naomi Murai

8

1 reference

3 August 2017

Shin-ichiro Egashira

9

1 reference

3 August 2017

Takashi Murai

10

1 reference

3 August 2017

Yuko Mitobe

11

1 reference

3 August 2017

Hiroko Matsushita

12

1 reference

3 August 2017

Osamu Okamoto

13

1 reference

3 August 2017

Nagaaki Sato

14

1 reference

3 August 2017

Makoto Jitsuoka

15

1 reference

3 August 2017

Takahiro Fukuroda

16

1 reference

3 August 2017

Tomoyuki Ohe

17

1 reference

3 August 2017

Xiaoming Guan

18

1 reference

3 August 2017

Douglas J MacNeil

19

1 reference

3 August 2017

Lex H T Van der Ploeg

20

1 reference

3 August 2017

Masaru Nishikibe

21

1 reference

3 August 2017

Yasuyuki Ishii

22

1 reference

3 August 2017

Masaki Ihara

23

1 reference

3 August 2017

Takehiro Fukami

24

1 reference

3 August 2017

language of work or name

English

0 references

publication date

24 April 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

1 reference

3 August 2017

volume

103

1 reference

3 August 2017

issue

18

1 reference

3 August 2017

page(s)

7154-7158

1 reference

Gut hormone PYY(3-36) physiologically inhibits food intake

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Obesity--a genetic disease of adipose tissue?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Role of the Y1 receptor in the regulation of neuropeptide Y-mediated feeding: comparison of wild-type, Y1 receptor-deficient, and Y5 receptor-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Hypothalamic obesity: multiple routes mediated by loss of function in medial cell groups

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Role of the Y5 neuropeptide Y receptor in feeding and obesity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Down-regulated NPY receptor subtype-5 mRNA expression in genetically obese mouse brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Y-receptor subtypes--how many more?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Regionally-selective down-regulation of NPY receptor subtypes in the obese Zucker rat. Relationship to the Y5 'feeding' receptor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Diet-induced obese mice develop peripheral, but not central, resistance to leptin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

A receptor subtype involved in neuropeptide-Y-induced food intake

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Storage and expenditure of energy in obesity and their implications for management

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Increased hypothalamic content of preproneuropeptide Y messenger ribonucleic acid in genetically obese Zucker rats and its regulation by food deprivation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Hypothalamic neuropeptide Y gene expression in rats on scheduled feeding regimen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459032

Design and synthesis of the potent, orally available, brain-penetrable arylpyrazole class of neuropeptide Y5 receptor antagonists

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

In vitro and in vivo characterization of 3-[2-[6-(2-tert-butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl]benzonitrile hydrochloride salt, a potent and selective NPY5 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Reciprocal regional changes in brain NPY receptor density during dietary restriction and dietary-induced obesity in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Induction of neuropeptide Y expression in dorsomedial hypothalamus of diet-induced obese mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

L-152,804: orally active and selective neuropeptide Y Y5 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Characterization of Neuropeptide Y (NPY) Y5 Receptor-Mediated Obesity in Mice: Chronic Intracerebroventricular Infusion ofd-Trp34NPY

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Reduced food intake in response to CGP 71683A may be due to mechanisms other than NPY Y5 receptor blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Structure–activity relationship studies on 2-heteroaryl-4-arylimidazoles NPY5 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Environmental contributions to the obesity epidemic

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510320103

Activation of the NPY Y5 receptor regulates both feeding and energy expenditure

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16636293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Obesity as an adaptation to a high-fat diet: evidence from a cross-sectional study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16636293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0510320103

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference