Discovery of novel antigiardiasis drug candidates (Q34597506)

3 August 2017

Discovery of novel antigiardiasis drug candidates (English)

1 reference

3 August 2017

4

1 reference

3 August 2017

6

1 reference

3 August 2017

Osnat Herzberg

7

0 references

Juan Jose Marugan

series ordinal

5

object named as

Juan J Marugan

1 reference

3 August 2017

1

Liudmila Kulakova

1 reference

3 August 2017

Andrey Galkin

2

1 reference

PubMed ID

25267663

3 August 2017

Catherine Z Chen

series ordinal

3

1 reference

PubMed ID

25267663

3 August 2017

language of work or name

English

0 references

publication date

29 September 2014

1 reference

Antimicrobial Agents and Chemotherapy

3 August 2017

1 reference

3 August 2017

58

1 reference

3 August 2017

7303-7311

1 reference

3 August 2017

12

1 reference

Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Ascending dose-controlled trial of beloranib, a novel obesity treatment for safety, tolerability, and weight loss in obese women.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

A homogenous luminescence assay reveals novel inhibitors for giardia lamblia carbamate kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

High-throughput Giardia lamblia viability assay using bioluminescent ATP content measurements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Fumagillin for treatment of intestinal microsporidiosis in renal transplant recipients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Structure of a microsporidian methionine aminopeptidase type 2 complexed with fumagillin and TNP-470

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Prevalence of recurring symptoms after infection with Giardia lamblia in a non-endemic area

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Arsenic-based antineoplastic drugs and their mechanisms of action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Dose translation from animal to human studies revisited

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Giardia and Cryptosporidium join the 'Neglected Diseases Initiative'.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Structural basis for the functional differences between type I and type II human methionine aminopeptidases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Fumagillin treatment of intestinal microsporidiosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Drug targets and mechanisms of resistance in the anaerobic protozoa

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

7 July 2018

Treatment of giardiasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Structure of human methionine aminopeptidase-2 complexed with fumagillin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Efficacies of zinc-finger-active drugs against Giardia lamblia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Vesicular neurotransmitter transporters. Potential sites for the regulation of synaptic function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Giardia lamblia infections in adult mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Giardia lamblia infection of suckling mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Functional characterization of intestinal intraepithelium & lamina propria lymphocytes from Giardia lamblia infected mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) is a naturally occurring protein-tyrosine kinase inhibitor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Restriction-endonuclease analysis of DNA from 15 Giardia isolates obtained from humans and animals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Gut-associated immune effector responses in immunocompetent and immunocompromised mice with Giardia lamblia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Induction of metronidazole and furazolidone resistance in Giardia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Fumagillin reduces adipose tissue formation in murine models of nutritionally induced obesity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

The treatment of giardiasis in children: single-dose tinidazole compared with 3 days of nitazoxanide.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Characterisation of benzimidazole binding with recombinant tubulin from Giardia duodenalis, Encephalitozoon intestinalis, and Cryptosporidium parvum

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Control of nosema disease of honeybees with fumagillin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Metronidazole and albendazole susceptibility of 11 clinical isolates of Giardia duodenalis from France.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4249522

Sequential changes of lamina propria immunoglobulin-containing cells in immune intact and immunosuppressed mice infected with Giardia lamblia

26 October 2018

1 reference

12 December 2020

Treatment of microsporidial keratoconjunctivitis with topical fumagillin

1 reference

12 December 2020

Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent

1 reference

12 December 2020

Characterization of the biochemical properties of two methionine aminopeptidases of Cryptosporidium parvum

1 reference

12 December 2020

Generation of nitro radical anions of some 5-nitrofurans, and 2- and 5-nitroimidazoles by rat hepatocytes

1 reference

12 December 2020

The treatment of amebiasis with fumagillin

1 reference

12 December 2020

Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine

1 reference

12 December 2020

Axenic culture of Giardia lamblia in TYI-S-33 medium supplemented with bile

1 reference

12 December 2020

Variable virulence of isolates of Giardia lamblia in mice

1 reference

12 December 2020

A randomized, controlled, open-label trial of a single day of mebendazole versus a single dose of tinidazole in the treatment of giardiasis in children

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.03834-14

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

25267663