An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production (Q34592824)

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English	An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production (English)

1 reference

Europe PubMed Central

3 August 2017

endoplasmic reticulum

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1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

Ho Seong Seo

4

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author name string

Young-Il Kim

1

1 reference

Europe PubMed Central

3 August 2017

Kyungho Park

2

1 reference

Europe PubMed Central

3 August 2017

Jong Youl Kim

3

1 reference

Europe PubMed Central

3 August 2017

Kyong-Oh Shin

5

1 reference

Europe PubMed Central

3 August 2017

Yong-Moon Lee

6

1 reference

Europe PubMed Central

3 August 2017

Walter M Holleran

7

1 reference

Europe PubMed Central

3 August 2017

Peter M Elias

8

1 reference

Europe PubMed Central

3 August 2017

Yoshikazu Uchida

9

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Europe PubMed Central

3 August 2017

language of work or name

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publication date

13 October 2014

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Europe PubMed Central

3 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

3 August 2017

34

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Europe PubMed Central

3 August 2017

24

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Europe PubMed Central

3 August 2017

4368-4378

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Europe PubMed Central

3 August 2017

Evolving concepts in cancer therapy through targeting sphingolipid metabolism

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7 July 2018

Sphingosine 1-phosphate signalling

1 reference

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Src is activated by the nuclear receptor peroxisome proliferator-activated receptor β/δ in ultraviolet radiation-induced skin cancer

1 reference

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Ceramide signaling in mammalian epidermis

1 reference

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7 July 2018

The role of ceramide-1-phosphate in biological functions

1 reference

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7 July 2018

Ceramide 1-phosphate induces macrophage chemoattractant protein-1 release: involvement in ceramide 1-phosphate-stimulated cell migration

1 reference

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7 July 2018

A novel role of a lipid species, sphingosine-1-phosphate, in epithelial innate immunity.

1 reference

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Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses

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Development of a highly selective c-Src kinase inhibitor

1 reference

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Regulation of cathelicidin antimicrobial peptide expression by an endoplasmic reticulum (ER) stress signaling, vitamin D receptor-independent pathway

1 reference

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Cyclooxygenase-2 enhances antimicrobial peptide expression and killing of Staphylococcus aureus

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The human cathelicidin hCAP18/LL-37: a multifunctional peptide involved in mycobacterial infections

1 reference

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Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

1 reference

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AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

1 reference

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Chain length specificity for activation of cPLA2alpha by C1P: use of the dodecane delivery system to determine lipid-specific effects.

1 reference

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Role of ceramide kinase in peroxisome proliferator-activated receptor beta-induced cell survival of mouse keratinocytes

1 reference

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Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers

1 reference

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IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3.

1 reference

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Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells

1 reference

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Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3

1 reference

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Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes

1 reference

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Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation

1 reference

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Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

1 reference

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1 reference

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STATs in oncogenesis

1 reference

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Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia

1 reference

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7 July 2018

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

1 reference

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7 July 2018

Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages

1 reference

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1 reference

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Transcriptional regulation of beta-defensin gene expression in tracheal epithelial cells

1 reference

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

1 reference

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Expression of v-src in mammary epithelial cells induces transcription via STAT3

1 reference

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c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells

1 reference

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The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders

1 reference

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

1 reference

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Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: antagonism by cell-permeable ceramides

1 reference

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7 July 2018

Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

1 reference

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Ceramide-1-phosphate regulates migration of multipotent stromal cells and endothelial progenitor cells--implications for tissue regeneration

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Effects of S1P on skeletal muscle repair/regeneration during eccentric contraction

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27 October 2018

Hydrolytic pathway protects against ceramide-induced apoptosis in keratinocytes exposed to UVB.

1 reference

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Alteration of sphingolipid metabolism and pSTAT3 expression by dietary cholesterol in the gallbladder of hamsters

1 reference

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Ceramide 1-phosphate inhibits serine palmitoyltransferase and blocks apoptosis in alveolar macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248733

27 October 2018

UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo.

1 reference

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Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement

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Involvement of nitric oxide in the promotion of cell survival by ceramide 1-phosphate.

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Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domain

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Effects of ceramide-1-phosphate on cultured cells: dependence on dodecane in the vehicle.

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Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli.

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27 October 2018

Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2 alpha and enhances the interaction of the enzyme with phosphatidylcholine.

1 reference

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Glucosylceramide synthesis and synthase expression protect against ceramide-induced stress.

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Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2

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https://pubmed.ncbi.nlm.nih.gov/25312644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing

1 reference

https://pubmed.ncbi.nlm.nih.gov/25312644

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Sphingosine 1-phosphate stimulates proliferation and migration of satellite cells: role of S1P receptors

1 reference

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inferred from PubMed ID database lookup

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10.1128/MCB.00599-14

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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