De-regulation of JNK and JAK/STAT signaling in ESCRT-II mutant tissues cooperatively contributes to neoplastic tumorigenesis (Q34589732)

3 August 2017

De-regulation of JNK and JAK/STAT signaling in ESCRT-II mutant tissues cooperatively contributes to neoplastic tumorigenesis (English)

1 reference

3 August 2017

Sarah E Woodfield

1

1 reference

3 August 2017

Hillary K Graves

series ordinal

2

1 reference

3 August 2017

Jacob A Hernandez

series ordinal

3

1 reference

3 August 2017

Andreas Bergmann

series ordinal

4

1 reference

3 August 2017

language of work or name

English

0 references

publication date

13 February 2013

1 reference

3 August 2017

1 reference

3 August 2017

8

1 reference

3 August 2017

2

1 reference

3 August 2017

e56021

1 reference

Creative Commons Attribution 4.0 International

3 August 2017

start time

13 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis

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Notch signaling activates Yorkie non-cell autonomously in Drosophila

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Tumor suppression by cell competition through regulation of the Hippo pathway

7 July 2018

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Drosophila endocytic neoplastic tumor suppressor genes regulate Sav/Wts/Hpo signaling and the c-Jun N-terminal kinase pathway

7 July 2018

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A dp53/JNK-dependant feedback amplification loop is essential for the apoptotic response to stress in Drosophila

7 July 2018

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7 July 2018

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The NAB-Brk signal bifurcates at JNK to independently induce apoptosis and compensatory proliferation

7 July 2018

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Genetic interactions between the Drosophila tumor suppressor gene ept and the stat92E transcription factor

7 July 2018

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Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants

7 July 2018

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Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila

7 July 2018

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Disruption of Vps4 and JNK function in Drosophila causes tumour growth

7 July 2018

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Common and distinct genetic properties of ESCRT-II components in Drosophila

7 July 2018

1 reference

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Chmp1A functions as a novel tumor suppressor gene in human embryonic kidney and ductal pancreatic tumor cells

7 July 2018

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Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45.

7 July 2018

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Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

7 July 2018

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A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation

7 July 2018

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bicoid RNA localization requires specific binding of an endosomal sorting complex

7 July 2018

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Metastatic ability of Drosophila tumors depends on MMP activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Cell cycle kinases in cancer

7 July 2018

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Up-regulation of tumor susceptibility gene 101 protein in ovarian carcinomas revealed by proteomics analyses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila

7 July 2018

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The ESCRT complexes: structure and mechanism of a membrane-trafficking network

7 July 2018

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ARK, the Apaf-1 related killer in Drosophila, requires diverse domains for its apoptotic activity

7 July 2018

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vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Neuroendocrine-like differentiation of non-small cell lung carcinoma cells: regulation by cAMP and the interaction of mac25/IGFBP-rP1 and 25.1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Endocytic control of epithelial polarity and proliferation in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation

7 July 2018

1 reference

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Molecular targets for tumour progression in gastrointestinal stromal tumours

7 July 2018

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A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway

7 July 2018

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HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein

7 July 2018

1 reference

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STAT proteins: From normal control of cellular events to tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

The Drosophila cyclin D-Cdk4 complex promotes cellular growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Neuroectodermal transcription of the Drosophila neurogenic genes E(spl) and HLH-m5 is regulated by proneural genes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

SnapShot: the ESCRT machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

A model Notch response element detects Suppressor of Hairless-dependent molecular switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

The endocytic control of JAK/STAT signalling in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

The Drosophila cytokine receptor Domeless controls border cell migration and epithelial polarization during oogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572140

Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing

27 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0056021

Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23418496

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis of the Drosophila larva

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23418496

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tsg101 is upregulated in a subset of invasive human breast cancers and its targeted overexpression in transgenic mice reveals weak oncogenic properties for mammary cancer initiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23418496

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0056021

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference