A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. (Q34582206)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Yinghong Gao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Stephen P Davies

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Martin Augustin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Anna Woodward

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Umesh A Patel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Robert Kovelman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

1 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

number of pages

16

1 reference

based on heuristic

inferred from page(s)

published in

Biochemical Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

451

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

313-328

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

The protein kinase complement of the human genome

23 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Targeting cancer with small molecule kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

The (un)targeted cancer kinome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Spleen tyrosine kinases: biology, therapeutic targets and drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Rapamycin passes the torch: a new generation of mTOR inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Identifying compound-target associations by combining bioactivity profile similarity search and public databases mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Aromatic interactions with phenylalanine 691 and cysteine 828: a concept for FMS-like tyrosine kinase-3 inhibition. Application to the discovery of a new class of potential antileukemia agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Targeting the cancer kinome through polypharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

The art of the chemical probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

A quantitative analysis of kinase inhibitor selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Comprehensive analysis of kinase inhibitor selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

In situ kinase profiling reveals functionally relevant properties of native kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Proteomics strategy for quantitative protein interaction profiling in cell extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

The specificities of protein kinase inhibitors: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

The selectivity of protein kinase inhibitors: a further update

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

The evolution of protein kinase inhibitors from antagonists to agonists of cellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Features of selective kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Discovery and development of spleen tyrosine kinase (SYK) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

c-Jun and the transcriptional control of neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

A small molecule-kinase interaction map for clinical kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Regulation and functions of Rho-associated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Critical role of nuclear calcium/calmodulin-dependent protein kinase IIdeltaB in cardiomyocyte survival in cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Selective killing of p53-deficient cancer cells by SP600125.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Identification of DNA methylation changes associated with human gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

PAS kinase: integrating nutrient sensing with nutrient partitioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

PAS kinase promotes cell survival and growth through activation of Rho1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20121418

21 January 2018

Identifiers

DOI

10.1042/BJ20121418

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23398362%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference