Human exposure to heterocyclic amine food mutagens/carcinogens: relevance to breast cancer (Q34580683)

3 August 2017

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title

Human exposure to heterocyclic amine food mutagens/carcinogens: relevance to breast cancer (English)

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2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

3 August 2017

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ChEBI release 2020-05-28

James S Felton

1

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3 August 2017

Mark G Knize

2

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3 August 2017

Cynthia P Salmon

3

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3 August 2017

Michael A Malfatti

4

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3 August 2017

Kristen S Kulp

5

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3 August 2017

1 January 2002

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Environmental and Molecular Mutagenesis

3 August 2017

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3 August 2017

39

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3 August 2017

2-3

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3 August 2017

112-118

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Carcinogenicity of 2-Amino-3-methylimidazo[4,5-f]quinoline in Nonhuman Primates: Induction of Tumors in Three Macaques

3 August 2017

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Induction of hepatocellular carcinoma in nonhuman primates by the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline

21 January 2018

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Mutagenicity of food pellets from human diets in The Netherlands

21 January 2018

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Induction of lymphoma in CDF1 mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

21 January 2018

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A carcinogenic heterocyclic amine, common in food, and its metabolites are found in rodent breast milk and urine of the suckling pups.

21 January 2018

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Occurrence, identification, and bacterial mutagenicity of heterocyclic amines in cooked food

21 January 2018

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Isolation and characterization of new mutagens from fried ground beef

21 January 2018

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The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

21 January 2018

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Report on the first international workshop on carcinoma-associated mucins

21 January 2018

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Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): formation of 2-hydroxamino-PhIP, a directly acting genotoxic metabolite

21 January 2018

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Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.

21 January 2018

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The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1

21 January 2018

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Effects of temperature, patty thickness and fat content on the production of mutagens in fried ground beef

21 January 2018

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A comparison of mutagen production in fried ground chicken and beef: effect of supplemental creatine

21 January 2018

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The metabolism of 4,8-DiMeIQx in conventional and germ-free rats.

21 January 2018

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Formation of mutagenic activity from amino acids heated at cooking temperatures.

21 January 2018

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Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans

21 January 2018

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Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research

21 January 2018

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The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

21 January 2018

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N-glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N_hydroxy-PhIP by specific human UDP-glucuronosyltransferases

21 January 2018

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Detection of a carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in cigarette smoke condensate.

21 January 2018

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Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.

21 January 2018

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Activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b] pyridine by cDNA-expressed human and rat arylsulfotransferases.

21 January 2018

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Re: "Fried foods and the risk of colon cancer".

21 January 2018

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Overview of carcinogenic heterocyclic amines

21 January 2018

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The metabolic disposition of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the induced mouse

21 January 2018

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Genetically modified Chinese hamster ovary cells for investigating sulfotransferase-mediated cytotoxicity and mutation by 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine

21 January 2018

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Differential effect of acetyltransferase expression on the genotoxicity of heterocyclic amines in CHO cells

21 January 2018

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STRUCTURE OF A POTENT MUTAGEN ISOLATED FROM FRIED BEEF

21 January 2018

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An XAD-2 resin method for efficient extraction of mutagens from fried ground beef

21 January 2018

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Role of sulfation and acetylation in the activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine to intermediates which bind DNA

21 January 2018

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Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human

21 January 2018

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Quantitation of mutagenic/carcinogenic heterocyclic aromatic amines in food products

21 January 2018

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Chromatographic methods for the analysis of heterocyclic amine food mutagens/carcinogens

21 January 2018

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The identification of [2-(14)C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans

21 January 2018

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Detection of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in beer and wine

21 January 2018

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Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods

21 January 2018

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The epidemiological evidence concerning intake of mutagenic activity from the fried surface and the risk of cancer cannot justify preventive measures.

21 January 2018

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The direct glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) by human and rabbit liver microsomes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/EM.10070

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3 August 2017

1 reference