Transcriptional and post-transcriptional mechanisms of glucocorticoid antiproliferative effects (Q34580606)

3 August 2017

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title

Transcriptional and post-transcriptional mechanisms of glucocorticoid antiproliferative effects (English)

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3 August 2017

Wassim Y Almawi

1

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PubMed ID

11921014

3 August 2017

Maroun M Abou Jaoude

series ordinal

2

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PubMed ID

11921014

3 August 2017

Xian C Li

series ordinal

3

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3 August 2017

1 March 2002

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3 August 2017

Hematological Oncology

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3 August 2017

20

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3 August 2017

17-32

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3 August 2017

1

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Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates

3 August 2017

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Dexamethasone up-regulates type II IL-1 receptor in mouse primary activated astrocytes.

21 January 2018

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Glucocorticoids inhibit proliferation and adhesion of the IL-3-dependent mast cell line, MC/9, to NIH/3T3 fibroblasts, with an accompanying decrease in IL-3 receptor expression

21 January 2018

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The interleukin-1 type 2 receptor gene displays immediate early gene responsiveness in glucocorticoid-stimulated human epidermal keratinocytes

21 January 2018

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Immunobiology and immunopharmacology of organ allograft rejection

21 January 2018

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The three-dimensional structure of peptide-MHC complexes

21 January 2018

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Complex complexes: signaling at the TCR.

21 January 2018

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Opening a window on thymic positive selection: developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement

21 January 2018

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CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

21 January 2018

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CD4 augments the response of a T cell to agonist but not to antagonist ligands

21 January 2018

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The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

21 January 2018

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Antigen-specific regulation of T cell-mediated cytokine production

21 January 2018

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T cell antigen receptor signal transduction pathways

21 January 2018

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Crosstalk among multiple signal-activated phospholipases

21 January 2018

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Protein modules and signalling networks

21 January 2018

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The regulation and function of p21ras during T-cell activation and growth.

21 January 2018

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

21 January 2018

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Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

21 January 2018

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NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats

21 January 2018

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Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

21 January 2018

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The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer

21 January 2018

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MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

21 January 2018

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T cell antigen receptor activation pathways: The tyrosine kinase connection

21 January 2018

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Expression of interleukin-16 by human epithelial cells. Inhibition by dexamethasone.

21 January 2018

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Production of macrophage colony-stimulating factor (M-CSF) by human articular cartilage and chondrocytes. Modulation by interleukin-1 and tumor necrosis factor alpha.

21 January 2018

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Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcription

21 January 2018

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Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids

21 January 2018

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Possible differences in the mechanism(s) of action of different glucocorticoid hormone compounds

21 January 2018

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DNA binding specificity of steroid receptors.

21 January 2018

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Effect of corticosteroids, cyclosporin A, and methotrexate on cytokine release from monocytes and T-cell subsets

21 January 2018

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Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

21 January 2018

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Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer

21 January 2018

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Negative regulation of interleukin 2 transcription by the glucocorticoid receptor

21 January 2018

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A functional glucocorticoid-responsive unit composed of two overlapping inactive receptor-binding sites: evidence for formation of a receptor tetramer

21 January 2018

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Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

21 January 2018

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Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements

21 January 2018

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The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter

21 January 2018

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Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT.

21 January 2018

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Glucocorticoid induction of CRE-binding protein isoform mRNAs in rat C6 glioma cells

21 January 2018

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Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.

21 January 2018

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Identification of two distinct nuclear factors with DNA binding activity within the glucocorticoid regulatory region of the rat alpha-1-acid glycoprotein promoter

21 January 2018

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Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

21 January 2018

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Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

21 January 2018

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Transrepression of NF-kappaB is not required for glucocorticoid-mediated protection of TNF-alpha-induced apoptosis on fibroblasts.

21 January 2018

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Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA.

21 January 2018

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Post-transcriptional control of c-myc proto-oncogene expression by glucocorticoid hormones in human T lymphoblastic leukemic cells

21 January 2018

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T cell receptor-independent immunosuppression induced by dexamethasone in murine T helper cells

21 January 2018

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Glucocorticoid-mediated inhibition of interleukin-2 receptor alpha and -beta subunit expression by human T cells

21 January 2018

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Interleukin-2 induces gamma-S-adenosyl-L-methionine synthetase gene expression during T-lymphocyte activation

21 January 2018

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Functional diversity of helper T lymphocytes

21 January 2018

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

21 January 2018

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Biology of human TH1 and TH2 cells

21 January 2018

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Regulation of T helper cell cytokine expression: functional dichotomy of antigen-presenting cells.

21 January 2018

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

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Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

21 January 2018

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Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

21 January 2018

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Th1 and Th2 subsets: paradigms lost?

21 January 2018

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Manipulation of cytokine networks in transplantation: false hope or realistic opportunity for tolerance?

21 January 2018

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Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement

21 January 2018

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Brief report: clonal proliferation of type 2 helper T cells in a man with the hypereosinophilic syndrome

21 January 2018

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Lymphokine production by human T cells in disease states

21 January 2018

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Subsets of CD4+T Cells and their Roles in the Induction and Prevention of Autoimmunity

21 January 2018

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Disruption of Th1/Th2 cytokine balance by cocaine is mediated by corticosterone

21 January 2018

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Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4.

21 January 2018

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Human Th1 cells preferentially induce interleukin (IL)-1beta while Th2 cells induce IL-1 receptor antagonist production upon cell/cell contact with monocytes

21 January 2018

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Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist

21 January 2018

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Selective expression of an interleukin-12 receptor component by human T helper 1 cells

21 January 2018

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Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12.

21 January 2018

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Regulation of transforming growth factor-beta 1 gene expression by glucocorticoids in normal human T lymphocytes

21 January 2018

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Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. Transforming growth factor-beta 3

21 January 2018

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Glucocorticoid-mediated repression of cytokine gene transcription in human arteritis-SCID chimeras

21 January 2018

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Dexamethasone-induced increase in platelet-derived growth factor (B) mRNA in human alveolar macrophages and myelomonocytic HL60 macrophage-like cells

21 January 2018

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Differential regulation of the expression of transforming growth factor-beta s 1 and 2 by retinoic acid, epidermal growth factor, and dexamethasone in NRK-49F and A549 cells.

21 January 2018

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Effects of dexamethasone on the expression of transforming growth factor-beta in mouse embryonic palatal mesenchymal cells

21 January 2018

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Transforming growth factor beta 1 augments mitogen-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene both in Swiss 3T3 cells and in murine embryo fibroblasts

21 January 2018

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Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3

21 January 2018

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Transforming growth factor beta (TGF-beta) and dexamethasone have direct opposing effects on collagen metabolism in low passage human dermal fibroblasts in vitro

21 January 2018

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Comparative study of lymphocyte-suppressive potency between prednisolone and methylprednisolone in rheumatoid arthritis

21 January 2018

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A combination of anti-interleukin 6 murine monoclonal antibody with dexamethasone and high-dose melphalan induces high complete response rates in advanced multiple myeloma

21 January 2018

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Randomized comparison of unfractionated heparin with corticosteroids in severe active inflammatory bowel disease

21 January 2018

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The balance of protein kinase C and calcium signaling directs T cell subset development

21 January 2018

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Duration of TCR stimulation determines costimulatory requirement of T cells

21 January 2018

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Glucocorticoids inhibit calcium- and calcineurin-dependent activation of the human IL-4 promoter

21 January 2018

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Glucocorticoids suppressed production and gene expression of interleukin-5 by peripheral blood mononuclear cells in atopic patients and normal subjects

21 January 2018

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Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha

21 January 2018

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Immunosuppression by glucocorticoids: inhibition of production of multiple lymphokines by in vivo administration of dexamethasone

21 January 2018

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Selective inhibition of NF-kB activation and TNF-alpha production in macrophages by red blood cell-mediated delivery of dexamethasone

21 January 2018

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Co-localization of elements required for phorbol ester stimulation and glucocorticoid repression of proliferin gene expression

21 January 2018

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Induction of cyclooxygenase-2 by platelet-derived growth factor (PDGF) and its inhibition by dexamethasone are independent of NF-kappaB/IkappaB transcription factors

21 January 2018

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Interleukin-12 enhances contact hypersensitivity by modulating the in vivo cytokine pattern in mice

21 January 2018

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Cytokine mRNA expression in tolerant heart allografts after immunosuppression with cyclosporine, sirolimus or brequinar

21 January 2018

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Different modulation by histamine of IL-4 and interferon-gamma (IFN-gamma) release according to the phenotype of human Th0, Th1 and Th2 clones

21 January 2018

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Alterations in interleukin-4 and antibody production following pheromone exposure: role of glucocorticoids

21 January 2018

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Glucocorticosteroids affect functions of airway- and blood-derived human T-cell clones, favoring the Th1 profile through two mechanisms

21 January 2018

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Mediation of glucocorticoid receptor function by the activation of latent transforming growth factor beta 1 in MG-63 human osteosarcoma cells

21 January 2018

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Mediation of glucocorticoid receptor function by transforming growth factor beta I expression in human PC-3 prostate cancer cells

21 January 2018

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Glucocorticoid-induced activation of latent transforming growth factor-beta by normal human osteoblast-like cells

21 January 2018

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Dexamethasone abrogates the fibrogenic effect of transforming growth factor-beta in rat granuloma and granulation tissue fibroblasts

21 January 2018

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Regulation of cytokine and cytokine receptor expression by glucocorticoids

21 January 2018

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7 January 2021

Time course of inflammatory and remodeling events in a murine model of asthma: effect of steroid treatment

1 reference

7 January 2021

Posttranscriptional mechanisms of glucocorticoid antiproliferative effects: glucocorticoids inhibit IL-6-induced proliferation of B9 hybridoma cells.

1 reference

7 January 2021

Induction of IkappaBalpha mRNA expression in the brain by glucocorticoids: a negative feedback mechanism for immune-to-brain signaling

1 reference

7 January 2021

Identifiers

DOI

10.1002/HON.684

1 reference

3 August 2017

1 reference

PubMed ID

11921014