Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. (Q34571293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21172654%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer (English)

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18 January 2020

5

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18 January 2020

Cynthia Lopez-Haber

2

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18 January 2020

J. Silvio Gutkind

11

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18 January 2020

Ramon E Parsons

12

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author name string

Maria Soledad Sosa

1

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18 January 2020

Chengfeng Yang

3

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18 January 2020

Hongbin Wang

4

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18 January 2020

John M Busillo

6

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18 January 2020

Jiansong Luo

7

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18 January 2020

Jeffrey L Benovic

8

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18 January 2020

Andres Klein-Szanto

9

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18 January 2020

Hiroshi Yagi

10

1 reference

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18 January 2020

Marcelo G Kazanietz

13

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18 January 2020

publication date

1 December 2010

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18 January 2020

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18 January 2020

volume

40

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18 January 2020

page(s)

877-892

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18 January 2020

issue

6

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Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling

18 January 2020

cites work

1 reference

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Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase

7 July 2018

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Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function

7 July 2018

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HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated by transforming growth factor beta

7 July 2018

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Concordance among gene-expression-based predictors for breast cancer

7 July 2018

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Genomic alterations in lobular neoplasia: a microarray comparative genomic hybridization signature for early neoplastic proliferationin the breast

7 July 2018

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7 July 2018

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Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients

7 July 2018

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Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.

7 July 2018

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Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers

7 July 2018

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P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase

7 July 2018

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7 July 2018

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Pertussis toxin or phorbol 12-myristate 13-acetate can distinguish between epidermal growth factor- and angiotensin-stimulated signals in hepatocytes

7 July 2018

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Rapid release of bound glucose-6-phosphate dehydrogenase by growth factors. Correlation with increased enzymatic activity

7 July 2018

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7 July 2018

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Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo.

27 October 2018

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Reduced expression of PTEN correlates with breast cancer progression

27 October 2018

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27 October 2018

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G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor

27 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21172654

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2010.11.029

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21172654%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21172654%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference