FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A. (Q34566865)

3 August 2017

FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A. (English)

1 reference

3 August 2017

5

Sheelagh Frame

1 reference

3 August 2017

Thilo Hagen

1

1 reference

3 August 2017

Darren A E Cross

2

1 reference

3 August 2017

Ainsley A Culbert

3

1 reference

3 August 2017

Andrew West

4

1 reference

3 August 2017

Nick Morrice

6

1 reference

3 August 2017

Alastair D Reith

7

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3 August 2017

language of work or name

English

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publication date

18 September 2006

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Journal of Biological Chemistry

3 August 2017

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3 August 2017

281

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3 August 2017

46

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3 August 2017

35021-35029

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GSK3 takes centre stage more than 20 years after its discovery

3 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Missing links in GSK3 regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Regulation of GSK-3: a cellular multiprocessor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

The Wnt signaling pathway in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Identification of the Axin and Frat binding region of glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and beta-catenin stabilisation without elevation of glycogen synthase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Characterization and functional analysis of the murine Frat2 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

FRAT-2 preferentially increases glycogen synthase kinase 3 beta-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Frat is dispensable for canonical Wnt signaling in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

GBP binds kinesin light chain and translocates during cortical rotation in Xenopus eggs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

P24, a glycogen synthase kinase 3 (GSK 3) inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607003200

21 January 2018

Identifiers

DOI

10.1074/JBC.M607003200

1 reference

3 August 2017

1 reference