Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity (Q34560275)

3 August 2017

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title

Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity (English)

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3 August 2017

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Gary M Williams

1

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PubMed ID

11890475

3 August 2017

Michael J Iatropoulos

series ordinal

2

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PubMed ID

11890475

3 August 2017

language of work or name

English

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publication date

1 January 2002

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3 August 2017

Toxicologic Pathology

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3 August 2017

30

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3 August 2017

41-53

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3 August 2017

1

1 reference

The sensitivity of the NTP bioassay for carcinogen hazard evaluation can be modulated by dietary restriction.

3 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

The relationship among microsomal enzyme induction, liver weight and histological change in rat toxicology studies.

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230252824699

The multidrug resistance protein family.

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230252824699

Reactions of oxyl radicals with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Dose-response relationships of hepatic acyl-CoA oxidase and catalase activity and liver mitogenesis induced by the peroxisome proliferator ciprofibrate in C57BL/6N and BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Cell culture assays for chemicals with tumor-promoting or tumor-inhibiting activity based on the modulation of intercellular communication.

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230252824699

Hormesis: a highly generalizable and reproducible phenomenon with important implications for risk assessment.

21 January 2018

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https://api.crossref.org/works/10.1080%2F01926230252824699

Overview of structural and functional lesions in endocrine organs of animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Development and utilization of primary hepatocyte culture systems to evaluate metabolism, DNA binding, and DNA repair of xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Review of the hepatic response to hypolipidaemic drugs in rodents and assessment of its toxicological significance to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Selective protein arylation and acetaminophen-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Cell proliferation in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Principles underlying dose selection for, and extrapolation from, the carcinogen bioassay: dose influences mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Carcinogen-mediated oxidant formation and oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

In vivo induction of liver P-glycoprotein expression by xenobiotics in monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

The effects of dietary restriction on drug testing and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

21 January 2018

Toxic action/toxicity

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Structural, mechanistic and clinical aspects of MRP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Endocrine considerations in toxicologic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

21 January 2018

Proliferation markers

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Zonation of metabolism and gene expression in liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Role of rat strain in the differential sensitivity to pharmaceutical agents and naturally occurring substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Specific association of human telomerase activity with immortal cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Dose-response relationship of diethylnitrosamine-initiated tumors in neonatal balb/c mice: effect of phenobarbital promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Mitochondrial toxicity of antiviral drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Quality control by DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Phenobarbital-mediated changes in gene expression in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Mechanisms and regulation of bile secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

P450 genes: structure, evolution, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

DNA repair: kinetics and thresholds

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Concordance of the toxicity of pharmaceuticals in humans and in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Effect of rodent hepatocarcinogenic peroxisome proliferators on fatty acyl-CoA oxidase, DNA synthesis, and apoptosis in cultured human and rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Poly (ADP-ribose) polymerase, nitric oxide and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Bcl-2 and the regulation of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Rodent tumors of urinary bladder, renal cortex, and thyroid gland in IARC Monographs evaluations of carcinogenic risk to humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Further characterization of the ability of hepatocarcinogens to lower rat liver aryl sulfotransferase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Heat shock factors and the control of the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Enhancement of dimethylnitrosamine-initiated hepatocarcinogenesis in hamsters by subsequent administration of carbon tetrachloride but not phenobarbital or p,p'-dichlorodiphenyltrichloroethane

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Cell cycle-specific mutagenesis at the hypoxanthine phosphoribosyltransferase locus in adult rat liver epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Protective effect of rhIL-11 in a murine model of acetaminophen-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Peroxisome proliferator-activated receptors: structures and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Pentachlorophenol (PCP) produces liver oxidative stress and promotes but does not initiate hepatocarcinogenesis in B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Cell proliferation in the livers of male mice and rats exposed to the carcinogen P-dichlorobenzene: evidence for thresholds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Mitochondrial diseases in man and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Phenobarbital mechanistic data and risk assessment: enzyme induction, enhanced cell proliferation, and tumor promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Liver carcinogenesis: The role for some chemicals of an epigenetic mechanism of liver-tumour promotion involving modification of the cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Mechanistic basis for nonlinearities and thresholds in rat liver carcinogenesis by the DNA-reactive carcinogens 2-acetylaminofluorene and diethylnitrosamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Structure-activity relationships in the rat hepatocyte DNA-repair test for 300 chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Mechanism-based risk assessment of peroxisome proliferating rodent hepatocarcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

Gap junctional intercellular communication and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01926230252824699

10.1080/01926230252824699

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

11890475