Roles of the complement system in human neurodegenerative disorders: pro-inflammatory and tissue remodeling activities. (Q34560179)

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8 December 2019

review article

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title

Roles of the complement system in human neurodegenerative disorders: pro-inflammatory and tissue remodeling activities (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11890454%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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8 December 2019

Bryan Paul Morgan

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8 December 2019

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Sim K Singhrao

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8 December 2019

author name string

Jim W Neal

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8 December 2019

Yann D Dean

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8 December 2019

Beek Johan Van

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8 December 2019

Philippe Gasque

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8 December 2019

publication date

1 February 2002

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8 December 2019

published in

Molecular Neurobiology

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8 December 2019

volume

25

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8 December 2019

page(s)

1-17

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8 December 2019

issue

1

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https://scigraph.springernature.com/pub.10.1385/mn:25:1:001

8 December 2019

exact match

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cites work

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Arachidonic acid mobilization and phosphoinositide turnover by the terminal complement complex, C5b-9, in rat oligodendrocyte x C6 glioma cell hybrids.

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Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia

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beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain.

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Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.

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Inflammatory signals induce neurotrophin expression in human microglial cells

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Expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis

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Expression of CD59, a regulator of the membrane attack complex of complement, on human astrocytes.

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Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat.

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12 December 2020

Production and interferon-gamma-mediated regulation of complement component C2 and factors B and D by the astroglioma cell line U105-MG

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Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study.

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The expression of complement regulatory proteins by adult human oligodendrocytes

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Complement activation in amyloid plaques in Alzheimer's disease brains does not proceed further than C3.

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Differential expression of individual complement regulators in the brain and choroid plexus

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Nervous tissue as an immune compartment: the dialect of the immune response in the CNS.

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Complement gene expression in neuroblastoma and astrocytoma cell lines of human origin

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Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells

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12 December 2020

Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis.

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12 December 2020

Human astrocytes express membrane cofactor protein (CD46), a regulator of complement activation

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12 December 2020

Complement and cytokine gene expression in cultured microglial derived from postmortem human brains

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12 December 2020

Expression of cytokines by human astrocytomas following stimulation by C3a and C5a anaphylatoxins: specific increase in interleukin-6 mRNA expression

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Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide

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CD59 expression and complement susceptibility of human neuronal cell line (NTera2).

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Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein.

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Complement C5a anaphylatoxin fragment causes apoptosis in TGW neuroblastoma cells

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12 December 2020

Complement activation by beta-amyloid in Alzheimer disease

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12 December 2020

Killing of rat glial cells by complement: deficiency of the rat analogue of CD59 is the cause of oligodendrocyte susceptibility to lysis

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Vitronectin expression in Purkinje cells in the human cerebellum.

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12 December 2020

Complement biosynthesis in the central nervous system

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12 December 2020

Complement regulators C1 inhibitor and CD59 do not significantly inhibit complement activation in Alzheimer disease.

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12 December 2020

The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity

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12 December 2020

Detection of mosaic protein mRNA in human astrocytes.

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12 December 2020

Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts.

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12 December 2020

Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease.

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12 December 2020

Aspartate residue 7 in amyloid beta-protein is critical for classical complement pathway activation: implications for Alzheimer's disease pathogenesis

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12 December 2020

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12 December 2020

Primary cultures of murine astrocytes produce C3 and factor B, two components of the alternative pathway of complement activation.

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12 December 2020

Distribution of clusterin in Alzheimer brain tissue

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12 December 2020

Membrane proteins that protect against complement lysis

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12 December 2020

The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis.

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12 December 2020

Normal rat serum cytotoxicity against syngeneic oligodendrocytes. Complement activation and attack in the absence of anti-myelin antibodies.

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12 December 2020

Expression of the complement classical pathway by human glioma in culture. A model for complement expression by nerve cells.

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12 December 2020

Activation of Ras and mitogen-activated protein kinase pathway by terminal complement complexes is G protein dependent

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12 December 2020

The role of complement in disorders of the nervous system

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12 December 2020

Complement C1q and C3 mRNA expression in the frontal cortex of Alzheimer's patients

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12 December 2020

Detection of complement protein mRNA in human astrocytes by the polymerase chain reaction

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12 December 2020

C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited

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12 December 2020

Complement gene expression in human brain: comparison between normal and Alzheimer disease cases

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12 December 2020

The role of complement in inflammation and phagocytosis

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12 December 2020

Detection and cellular localization of human C4 gene expression in the renal tubular epithelial cells and other extrahepatic epithelial sources.

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12 December 2020

Expression of decay-accelerating factor (CD55), membrane cofactor protein (CD46) and CD59 in the human astroglioma cell line, D54-MG, and primary rat astrocytes

1 reference

12 December 2020

Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines

1 reference

12 December 2020

Detection of the membrane inhibitor of reactive lysis (CD59) in diseased neurons of Alzheimer brain

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12 December 2020

Role of complement in the aetiology of Pick's disease?

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12 December 2020

Complement regulatory protein expression by a human oligodendrocyte cell line: cytokine regulation and comparison with astrocytes.

1 reference

12 December 2020

Nonimmune activation of the classical complement pathway.

1 reference

12 December 2020

Expression of complement components of the alternative pathway by glioma cell lines

1 reference

12 December 2020

Expression of the complement membrane attack complex and its inhibitors in Pick disease brain

1 reference

12 December 2020

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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12 December 2020

Induction of decay-accelerating factor by cytokines or the membrane-attack complex protects vascular endothelial cells against complement deposition

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12 December 2020

Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

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12 December 2020

Extrahepatic complement biosynthesis: where, when and why?

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12 December 2020

An immunohistochemical study on cerebral vascular and senile plaque amyloid in Alzheimer’s dementia

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12 December 2020

Interferon-gamma regulation of C3 gene expression in human astroglioma cells

1 reference

12 December 2020

Activation of complement by myelin: identification of C1-binding proteins of human myelin from central nervous tissue

1 reference

12 December 2020

Identification and characterization of complement C3 receptors on human astrocytes

1 reference

12 December 2020

Differential regulation of C3 gene expression in human astroglioma cells by interferon-gamma and interleukin-1 beta

1 reference

12 December 2020

Complement C1 inhibitor is produced by brain tissue and is cleaved in Alzheimer disease

1 reference

12 December 2020

Membrane receptors for soluble defense collagens

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12 December 2020

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

1 reference

12 December 2020

Complement expression on astrocytes and astrocytoma cell lines: failure of complement regulation at the C3 level correlates with very low CD55 expression

1 reference

12 December 2020

Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain.

1 reference

12 December 2020

Expression of a functional anaphylatoxin C3a receptor by astrocytes.

1 reference

12 December 2020

Human oligodendrocytes are not sensitive to complement. A study of CD59 expression in the human central nervous system

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12 December 2020

Synergistic enhancement of chemokine generation and lung injury by C5a or the membrane attack complex of complement

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12 December 2020

Immunohistochemical localization of vitronectin, its receptor and beta-3 integrin in Alzheimer brain tissue

1 reference

12 December 2020

Soluble complement receptor 1 (sCR1) protects against experimental autoimmune myasthenia gravis

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12 December 2020

Activation of the classical complement pathway in brain tissue of Alzheimer patients

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12 December 2020