Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease? (Q34554945)

3 August 2017

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title

Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease? (English)

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3 August 2017

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Elizabeth J Coulson

1

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language of work or name

English

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publication date

1 August 2006

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Journal of Neurochemistry

3 August 2017

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3 August 2017

98

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3 August 2017

654-660

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3 August 2017

3

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Amyloid precursor protein modulates the interaction of nerve growth factor with p75 receptor and potentiates its activation of trkA phosphorylation

3 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Characterization of symmetric complexes of nerve growth factor and the ectodomain of the pan-neurotrophin receptor, p75NTR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The p75 neurotrophin receptor and neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Role of neurotrophin receptor p75NTR in mediating neuronal cell death following injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The p75 neurotrophin receptor: multiple interactors and numerous functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Expression of NGF receptor in the rat forebrain detected with in situ hybridization and immunohistochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38MAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

21 January 2018

Signaling to NF-kappaB

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Structure of nerve growth factor complexed with the shared neurotrophin receptor p75

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Increased hippocampal neurogenesis in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

A comparison of the cytoplasmic domains of the Fas receptor and the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Beta-amyloid binds to p57NTR and activates NFkappaB in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Regulation of cell survival by secreted proneurotrophins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

NMR structure of the death domain of the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Structure and function of amyloid in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

p75 nerve growth factor receptor immunoreactivity in the human brainstem and spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Low-affinity neurotrophin receptor with targeted mutation of exon 3 is capable of mediating the death of axotomized neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Sortilin is essential for proNGF-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

A pro-apoptotic fragment of the p75 neurotrophin receptor is expressed in p75NTRExonIV null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Role of p75 neurotrophin receptor in the neurotoxicity by beta-amyloid peptides and synergistic effect of inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Expression of the low-affinity nerve growth factor receptor enhances beta-amyloid peptide toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Neurotrophin signaling through the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Evidence for the participation of nerve growth factor and its low-affinity receptor (p75NTR) in the regulation of the myogenic program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Activity regulates positive and negative neurotrophin-derived signals to determine axon competition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Low concentrations of aggregated beta-amyloid induce neurite formation via the neurotrophin receptor p75.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Neurogenic effect of beta-amyloid peptide in the development of neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Deciphering the molecular basis of memory failure in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Activation of p75NTR by proBDNF facilitates hippocampal long-term depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Chopper, a New Death Domain of the p75 Neurotrophin Receptor That Mediates Rapid Neuronal Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The p75NTR mediates a bifurcated signal transduction cascade through the NF kappa B and JNK pathways to inhibit cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Critical role of brain-derived neurotrophic factor in mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

Neurotrophin signaling through the p75 receptor is deficient in traf6-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03905.X

10.1111/J.1471-4159.2006.03905.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

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PubMed ID

16893414