Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS (Q34545490)

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24 January 2020

title

Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS (English)

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24 January 2020

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5

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24 January 2020

Therese Becker

6

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24 January 2020

Xu Dong Zhang

11

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24 January 2020

author name string

C C Jiang

1

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24 January 2020

F Lai

2

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24 January 2020

K H Tay

3

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24 January 2020

A Croft

4

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24 January 2020

F Yang

7

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24 January 2020

H Liu

8

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24 January 2020

R F Thorne

9

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24 January 2020

P Hersey

10

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24 January 2020

publication date

2 September 2010

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24 January 2020

published in

Cell Death and Disease

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24 January 2020

volume

1

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24 January 2020

page(s)

e69

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2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2

24 January 2020

cites work

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The SR protein family

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Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax.

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7 July 2018

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Oncogenic BRAF(V600E) inhibits BIM expression to promote melanoma cell survival

7 July 2018

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7 July 2018

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7 July 2018

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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

7 July 2018

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Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis

7 July 2018

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Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

7 July 2018

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7 July 2018

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BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins

7 July 2018

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7 July 2018

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Signals, pathways and splicing regulation

7 July 2018

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Alternative splicing: an emerging topic in molecular and clinical oncology

7 July 2018

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Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanoma

7 July 2018

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Regulation of apoptosis by alternative pre-mRNA splicing

7 July 2018

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

7 July 2018

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Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40

7 July 2018

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The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Splicing factors are differentially expressed in tumors

27 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21364673

12 December 2020

inferred from PubMed ID database lookup

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK

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https://pubmed.ncbi.nlm.nih.gov/21364673

12 December 2020

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[Pre-mRNA alternative splicing in cancer: functional impact, molecular mechanisms and therapeutic perspectives]

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https://pubmed.ncbi.nlm.nih.gov/21364673

12 December 2020

inferred from PubMed ID database lookup

New stem cell center at Cornell

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https://api.crossref.org/works/10.1038%2FCDDIS.2010.48

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/CDDIS.2010.48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364673%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364673%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference