Cytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction tool (Q34542725)

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English	Cytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction tool	scientific article

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scholarly article

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24 February 2020

Cytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction tool (English)

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24 February 2020

Tengku Sifzizul Tengku Muhammad

2

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24 February 2020

Alexander Chong Shu-Chien

3

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24 February 2020

author name string

Xue Fen Koe

1

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24 February 2020

Habibah Abdul Wahab

4

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24 February 2020

Mei Lan Tan

5

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24 February 2020

publication date

10 June 2014

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24 February 2020

Food science & nutrition

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24 February 2020

2

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24 February 2020

5

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24 February 2020

500-520

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24 February 2020

Inhibition of CYP2C19 and CYP3A4 by omeprazole metabolites and their contribution to drug-drug interactions

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7 July 2018

Interactions between antiarrhythmic drugs and food

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7 July 2018

Induction of cytochrome P450 enzymes: a view on human in vivo findings

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7 July 2018

Fruit juices as perpetrators of drug interactions: the role of organic anion-transporting polypeptides

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7 July 2018

Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers

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Drug-nutrient interactions: a broad view with implications for practice

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Identification of the residue in human CYP3A4 that is covalently modified by bergamottin and the reactive intermediate that contributes to the grapefruit juice effect

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Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study

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Effects of Curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180.

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Correlation of mRNA and protein in complex biological samples.

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In vitro cytochrome P450 inhibition and induction

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Inhibition and induction of human cytochrome P450 enzymes: current status

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7 July 2018

Interactions of polyphenols with the P450 system: possible implications on human therapeutics

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7 July 2018

Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.

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The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects.

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7 July 2018

Identification of drugs that interact with herbs in drug development.

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7 July 2018

Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

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7 July 2018

Structural basis for ligand promiscuity in cytochrome P450 3A4.

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7 July 2018

CYP induction-mediated drug interactions: in vitro assessment and clinical implications

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7 July 2018

Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.

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7 July 2018

Drug interactions due to cytochrome P450.

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7 July 2018

High throughput P450 inhibition screens in early drug discovery

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Integrated genomic and proteomic analyses of gene expression in Mammalian cells

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Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

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Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

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7 July 2018

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

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7 July 2018

Effects of bergamottin on human and monkey drug-metabolizing enzymes in primary cultured hepatocytes

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7 July 2018

Metabolism profiling, and cytochrome P450 inhibition & induction in drug discovery

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Human drug metabolism and the cytochromes P450: application and relevance of in vitro models

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7 July 2018

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

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The human CYP3A subfamily: practical considerations

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A fluorescent cell-based assay for cytochrome P-450 isozyme 1A2 induction and inhibition

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7 July 2018

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

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Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

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Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450.

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Resveratrol affects CYP1A expression in rainbow trout hepatocytes

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Drug and nutrition interactions: not just food for thought

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Cytochrome P450 3A4 mRNA is a more reliable marker than CYP3A4 activity for detecting pregnane X receptor-activated induction of drug-metabolizing enzymes

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The induction of CYP1A2, CYP2D6 and CYP3A4 by six trade herbal products in cultured primary human hepatocytes

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Inhibition of CYP2D6 by quinidine and its effects on the metabolism of cilostazol

1 reference

https://pubmed.ncbi.nlm.nih.gov/25473508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Food-drug interactions: grapefruit juice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25473508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

St John's Wort: effect on CYP3A4 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25473508

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based on heuristic

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Mechanism-based inhibition of recombinant human cytochrome P450 3A4 by tomato juice extract

1 reference

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based on heuristic

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1 reference

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12 December 2020

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10.1002/FSN3.122

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24 February 2020

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24 February 2020

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24 February 2020

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