An assessment of mechanisms underlying peripheral axonal degeneration caused by aminoacyl-tRNA synthetase mutations (Q34538348)

2 August 2017

An assessment of mechanisms underlying peripheral axonal degeneration caused by aminoacyl-tRNA synthetase mutations (English)

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2 August 2017

7

Anthony Antonellis

1 reference

2 August 2017

Morgane Stum

1

1 reference

2 August 2017

Heather M McLaughlin

2

1 reference

2 August 2017

Erica L Kleinbrink

3

1 reference

2 August 2017

Kathy E Miers

4

1 reference

2 August 2017

Susan L Ackerman

5

1 reference

2 August 2017

Kevin L Seburn

6

1 reference

2 August 2017

Robert W Burgess

8

1 reference

2 August 2017

27 November 2010

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Molecular and Cellular Neuroscience

2 August 2017

1 reference

2 August 2017

46

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2 August 2017

2

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2 August 2017

432-443

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describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3030653/fullTextXML

inferred from PubMed Central ID database lookup

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GARS axonopathy: not every neuron's cup of tRNA

7 July 2018

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7 July 2018

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A major determinant for binding and aminoacylation of tRNA(Ala) in cytoplasmic Alanyl-tRNA synthetase is mutated in dominant axonal Charcot-Marie-Tooth disease

7 July 2018

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Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1

7 July 2018

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The C-Ala Domain Brings Together Editing and Aminoacylation Functions on One tRNA

7 July 2018

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Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy

7 July 2018

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An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy

7 July 2018

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The role of aminoacyl-tRNA synthetases in genetic diseases

7 July 2018

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Development of tRNA synthetases and connection to genetic code and disease

7 July 2018

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Function and regulation of local axonal translation

7 July 2018

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Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress

7 July 2018

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Local gene expression in axons and nerve endings: the glia-neuron unit

7 July 2018

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NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.

7 July 2018

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Distinct domains of tRNA synthetase recognize the same base pair

7 July 2018

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Deleterious mutation in the mitochondrial arginyl-transfer RNA synthetase gene is associated with pontocerebellar hypoplasia

7 July 2018

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Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect.

7 July 2018

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Long-range structural effects of a Charcot-Marie-Tooth disease-causing mutation in human glycyl-tRNA synthetase

7 July 2018

1 reference

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RNA transport and localized protein synthesis in neurological disorders and neural repair

7 July 2018

1 reference

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Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation

7 July 2018

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Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

7 July 2018

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Severe childhood SMA and axonal CMT due to anticodon binding domain mutations in the GARS gene

7 July 2018

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Global effects of mistranslation from an editing defect in mammalian cells

7 July 2018

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Functional analyses of glycyl-tRNA synthetase mutations suggest a key role for tRNA-charging enzymes in peripheral axons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030653

An active dominant mutation of glycyl-tRNA synthetase causes neuropathy in a Charcot-Marie-Tooth 2D mouse model

7 July 2018

1 reference

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Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration

7 July 2018

1 reference

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Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy

7 July 2018

1 reference

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Aminoacyl-tRNAs: setting the limits of the genetic code

7 July 2018

1 reference

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Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V.

7 July 2018

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Directed differentiation of embryonic stem cells into motor neurons

7 July 2018

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Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

7 July 2018

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Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis

7 July 2018

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Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine

7 July 2018

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An 85-kb tandem triplication in the slow Wallerian degeneration (Wlds) mouse

7 July 2018

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Crystal structure of glycyl-tRNA synthetase from Thermus thermophilus

7 July 2018

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The frequency of errors in protein biosynthesis

7 July 2018

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Embryonic mouse spinal cord motor neuron hybrid cells

7 July 2018

1 reference

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Editing of errors in selection of amino acids for protein synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030653

DARS2 mutations in mitochondrial leucoencephalopathy and multiple sclerosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030653

Cytoplasmic and mitochondrial protein translation in axonal and dendritic terminal arborization

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030653

Motoneurons derived from embryonic stem cells express transcription factors and develop phenotypes characteristic of medial motor column neurons.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030653

The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030653

Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21115117

12 December 2020

inferred from PubMed ID database lookup

Clinical and pathological phenotype of the original family with Charcot-Marie-Tooth type 1B: a 20-year study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21115117

12 December 2020

inferred from PubMed ID database lookup

Acute demyelination disrupts the molecular organization of peripheral nervous system nodes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21115117

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.MCN.2010.11.006

1 reference

2 August 2017

1 reference

2 August 2017

1 reference