Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow (Q34537621)

2 August 2017

Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow (English)

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2 August 2017

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Koizumi S

1

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2 August 2017

Curt GA

2

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2 August 2017

Fine RL

3

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2 August 2017

Griffin JD

4

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2 August 2017

Chabner BA

5

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2 August 2017

language of work or name

English

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publication date

1 March 1985

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Journal of Clinical Investigation

2 August 2017

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2 August 2017

75

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2 August 2017

1008-1014

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2 August 2017

3

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Protein measurement with the Folin phenol reagent

2 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Replacement of serum by insulin and transferrin supports growth and differentiation of the human promyelocytic cell line, HL-60

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Isolation of myeloid progenitor cells from peripheral blood of chronic myelogenous leukemia patients.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

The pharmacology and clinical use of methotrexate

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Transport, binding, and polyglutamation of methotrexate in freshly isolated rat hepatocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Threshold Methotrexate Concentration for In Vivo Inhibition of DNA Synthesis in Normal and Tumorous Target Tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Polygammaglutamyl metabolites of methotrexate.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Tissue-specific synthesis of methotrexate polyglutamates in the rat

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Accumulation of methotrexate diglutamate in human liver during methotrexate therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423648

Carrier-mediated Transport of the Folic Acid Analogue, Methotrexate, in the L1210 Leukemia Cell

7 July 2018

1 reference

12 December 2020

Monoclonal antibodies detecting antigenic determinants with restricted expression on erythroid cells: from the erythroid committed progenitor level to the mature erythroblast

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12 December 2020

Synthesis and retention of methotrexate polyglutamates by human small cell lung cancer

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12 December 2020

Polyglutamylation, an important element in methotrexate cytotoxicity and selectivity in tumor versus murine granulocytic progenitor cells in vitro

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12 December 2020

Prolonged inhibition of DNA synthesis associated with the accumulation of methotrexate polyglutamates by cultured human cells

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12 December 2020

Polyglutamate derivatives of folic acid coenzymes and methotrexate

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12 December 2020

Evidence for the cytotoxic activity of polyglutamate derivatives of methotrexate

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12 December 2020

Resistance of human bone marrow CFUC to high-dose methotrexate cytotoxicity

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12 December 2020

High-pressure liquid chromatography analysis of methotrexate polyglutamates in cultured human breast cancer cells

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12 December 2020

Differential synthesis of methotrexate polyglutamates in normal proliferative and neoplastic mouse tissues in vivo

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12 December 2020

Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro

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12 December 2020

Characteristics of methotrexate polyglutamate formation in cultured hepatic cells

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12 December 2020

Expression of Ia-like antigens defined by monoclonal OKIal antibody of hemopoietic progenitor cells in cord blood: a comparison with human bone marrow

1 reference

12 December 2020

Analysis of the role of membrane transport and polyglutamation of methotrexate in gut and the Ehrlich tumor in vivo as factors in drug sensitivity and selectivity

1 reference

12 December 2020

Methotrexate Metabolism by Bone Marrow Cells from Patients with Leukemia

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12 December 2020

Human bone marrow colony growth in agar-gel

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12 December 2020

Identifiers

DOI

10.1172/JCI111761

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2 August 2017

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2 August 2017

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