Autophagy is essential for effector CD8(+) T cell survival and memory formation (Q34516905)

2 August 2017

Autophagy is essential for effector CD8(+) T cell survival and memory formation (English)

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2 August 2017

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13

Herbert W Virgin

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2 August 2017

Lilin Ye

5

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Jennifer Martinez

object named as

Jennifer Martinez

9

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Douglas R. Green

object named as

Douglas R Green

11

0 references

Rafi Ahmed

14

object named as

Rafi Ahmed

1 reference

2 August 2017

Xiaojin Xu

1

1 reference

2 August 2017

Koichi Araki

2

1 reference

2 August 2017

Shuzhao Li

3

1 reference

2 August 2017

Jin-Hwan Han

4

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2 August 2017

Wendy G Tan

6

1 reference

2 August 2017

Bogumila T Konieczny

7

1 reference

2 August 2017

Monique W Bruinsma

8

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2 August 2017

Erika L Pearce

10

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2 August 2017

Dean P Jones

12

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2 August 2017

language of work or name

English

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publication date

2 November 2014

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2 August 2017

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2 August 2017

15

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2 August 2017

1152-1161

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2 August 2017

12

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Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Predicting network activity from high throughput metabolomics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy modulation as a potential therapeutic target for diverse diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Natural killer cells act as rheostats modulating antiviral T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy in immunity and inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Macroautophagy regulates energy metabolism during effector T cell activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Methods in mammalian autophagy research

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy in cellular growth control

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

mTOR regulates memory CD8 T-cell differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

apLCMS--adaptive processing of high-resolution LC/MS data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy regulates lipid metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

A critical role for the autophagy gene Atg5 in T cell survival and proliferation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thought

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Effector and memory CTL differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

The role of autophagy during the early neonatal starvation period

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Modelling T-cell memory by genetic marking of memory T cells in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Viral immune evasion due to persistence of activated T cells without effector function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

7 July 2018

1 reference

Autophagy is essential for mitochondrial clearance in mature T lymphocytes

21 January 2018

1 reference

Utilizing flow cytometry to monitor autophagy in living mammalian cells

21 January 2018

1 reference

Molecular and functional profiling of memory CD8 T cell differentiation.

21 January 2018

1 reference

IL-7 enhances the survival and maintains the size of naive T cells

21 January 2018

1 reference

Revving the engine: signal transduction fuels T cell activation.

21 January 2018

1 reference

Mitochondrial Potential and Reactive Oxygen Intermediates in Antigen-Specific CD8+ T Cells During Viral Infection

21 January 2018

1 reference

Mantle skewness and ridge segmentation

21 January 2018

1 reference

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

21 January 2018

1 reference

Genetic reconstitution of bone marrow for the study of signal transduction ex vivo.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232981

27 October 2018

Identifiers

DOI

10.1038/NI.3025

1 reference

2 August 2017

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2 August 2017

1 reference