ATC0175: an orally active melanin-concentrating hormone receptor 1 antagonist for the potential treatment of depression and anxiety. (Q34513909)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

ATC0175: an orally active melanin-concentrating hormone receptor 1 antagonist for the potential treatment of depression and anxiety (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Shigeyuki Chaki

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jun-ichi Yamaguchi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

William Thomsen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Thuy-Anh Tran

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Graeme Semple

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Yoshinori Sekiguchi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

1 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

CNS Neuroscience & Therapeutics

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

341-352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

Melanin-concentrating hormone (MCH) modifies memory retention in rats.

19 January 2020

cites work

1 reference

12 December 2020

The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat.

1 reference

12 December 2020

Effects of the CRF(1) receptor antagonist, CP 154,526, in the separation-induced vocalization anxiolytic test in rat pups.

1 reference

12 December 2020

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

1 reference

12 December 2020

Melanin-concentrating hormone stimulates the release of luteinizing hormone-releasing hormone and gonadotropins in the female rat acting at both median eminence and pituitary levels.

1 reference

12 December 2020

Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain

1 reference

12 December 2020

Melanin-concentrating hormone (MCH) suppresses thyroid stimulating hormone (TSH) release, in vivo and in vitro, via the hypothalamus and the pituitary

1 reference

12 December 2020

Anxiolytic properties of the selective, non-peptidergic CRF(1) antagonists, CP154,526 and DMP695: a comparison to other classes of anxiolytic agent

1 reference

12 December 2020

Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism

1 reference

12 December 2020

Assessing antidepressant activity in rodents: recent developments and future needs

1 reference

12 December 2020

Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity.

1 reference

12 December 2020

Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist

1 reference

12 December 2020

Do animal models of anxiety predict anxiolytic-like effects of antidepressants?

1 reference

12 December 2020

Effect of direct injection of melanin-concentrating hormone into the paraventricular nucleus: further evidence for a stimulatory role in the adrenal axis via SLC-1.

1 reference

12 December 2020

The vasopressin V1b receptor as a therapeutic target in stress-related disorders

1 reference

12 December 2020

Prospects for obesity treatment: MCH receptor antagonists.

1 reference

12 December 2020

A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep

1 reference

12 December 2020

Rat melanin-concentrating hormone stimulates adrenocorticotropin secretion: evidence for a site of action in brain regions protected by the blood-brain barrier

1 reference

12 December 2020

The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization

1 reference

12 December 2020

Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice.

1 reference

12 December 2020

Anxiolytic- and antidepressant-like profile of ATC0065 and ATC0175: nonpeptidic and orally active melanin-concentrating hormone receptor 1 antagonists

1 reference

12 December 2020

The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance.

1 reference

12 December 2020

Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive deficits and alterations of NMDA receptor function

1 reference

12 December 2020

Genetic inactivation of melanin-concentrating hormone receptor subtype 1 (MCHR1) in mice exerts anxiolytic-like behavioral effects

1 reference

12 December 2020

Melanin-concentrating hormone-1 receptor modulates neuroendocrine, behavioral, and corticolimbic neurochemical stress responses in mice

1 reference

12 December 2020

Evaluation of marble-burying behavior as a model of anxiety.

1 reference

12 December 2020

Endogenous hyperthermia in normal human subjects: experimental study of emotional states (II).

1 reference

12 December 2020

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

1 reference

12 December 2020

Melanin-concentrating hormone (MCH) involvement in pentylenetetrazole (PTZ)-induced seizure in rat and guinea pig

1 reference

12 December 2020

Mice lacking melanin-concentrating hormone are hypophagic and lean

1 reference

12 December 2020

10.1111/J.1527-3458.2005.TB00052.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16614734%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference