Assessment of the drug metabolism capacity of the liver (Q34511238)

2 August 2017

1 reference

title

Assessment of the drug metabolism capacity of the liver (English)

1 reference

2 August 2017

Park BK

1

1 reference

PubMed ID

6128018

2 August 2017

language of work or name

English

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publication date

1 November 1982

1 reference

British Journal of Clinical Pharmacology

2 August 2017

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2 August 2017

14

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2 August 2017

5

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2 August 2017

631-651

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EFFECT OF DIPHENYLHYDANTOIN ON CORTISOL METABOLISM IN MAN.

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Differential induction of antipyrine metabolism by rifampicin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Comparison of the in vivo and in vitro rates of formation of the three main oxidative metabolites of antipyrine in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

50 Analysis of bilirubin conjugates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Effect of isoniazid on vitamin D metabolism and hepatic monooxygenase activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

6 beta-hydroxycortisol excretion in relation to polymorphic N-oxidation of sparteine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Assay and characterisation of debrisoquine 4-hydroxylase activity of microsomal fractions of human liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Increased urinary D-glucaric acid excretion by children living in an area polluted with tetrachlorodibenzoparadioxin (TCDD).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Differential effects of enzyme induction on antipyrine metabolite formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

A simple pharmacokinetic method for separating the three acetylation phenotypes: a preliminary report

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Sparteine metabolism in Canadian Caucasians

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Defective oxidation of drugs: pharmacokinetic and therapeutic implications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Assessment of urinary 6 beta-hydroxycortisol as an in vivo index of mixed-function oxygenase activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Biochemical mechanisms in chemical-induced lung injury: roles of metabolic activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Impaired oxidation of debrisoquine in patients with perhexiline neuropathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Inhibition of antipyrine metabolism by beta-adrenoceptor antagonists

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Effect of low-dose phenobarbitone on five indirect indices of hepatic microsomal enzyme induction and plasma lipoproteins in normal subjects [letter]

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Partial purification and properties of the isoniazid transacetylase in human liver. Its relationship to the acetylation of p-aminosalicylic acid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Metabolism of drugs. LIX. A new metabolite of antipyrine.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Sulphadimidine Acetylation Test for Classification of Patients as Slow or Rapid Inactivators of Isoniazid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

An improved and simplified method of detecting the acetylator phenotype

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Drug‐metabolizing capacity in states of drug dependence and withdrawal

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Acute Stimulation of Cortisol Metabolism by Pentobarbital in Man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Effect of oral contraceptives on drug metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Stimulation of drug metabolism in man by tricyclic antidepressants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Urinary 17-Hydroxycorticosteroid Determination with p-Hydrazinobenzenesulfonic Acid–Phosphoric Acid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Determinants of serum antipyrine half-lives in patients with liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Immediate decrease by hydrocortisone of the plasma half-life of antipyrine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Urinary D-glucaric acid excretion and total liver content of cytochrome P-450 in guinea-pigs: Relationship during enzyme induction and following inhibition of protein synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

The Effect of Spironolactone on Antipyrine Metabolism in Man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Late toxicity to hydralazine resembling systemic lupus erythematosus or rheumatoid arthritis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Changes in D-glucaric acid excretion in relationship to alterations in the rate of antipyrine metabolism in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Methaqualone pharmacokinetics after single- and multiple-dose administration in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Clearance and biologic half-life as indices of intrinsic hepatic metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Changes in plasma -glutamyl transpeptidase activity associated with alterations in drug metabolism in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Factors affecting drug metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Stimulatory effect of cigarette smoking on the hydroxylation of 3,4-benzpyrene and the N-demethylation of 3-methyl-4-monomethylaminoazobenzene by enzymes in human placenta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Pharmacological implications of microsomal enzyme induction.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Increased clearance of antipyrine and d-propranolol after phenobarbital treatment in the monkey. Relative contributions of enzyme induction and increased hepatic blood flow

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Interindividual differences in drug oxidation: clinical importance.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Plasma gamma-glutamyl transpeptidase elevation in patients receiving enzyme-inducing drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

D-glucaric-acid excretion as a test for hepatic enzyme induction.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Test for Alcoholic Cirrhosis by Conversion of [14C] or [13C]Galactose to Expired CO2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Effect of smoking on theophylline disposition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Anomalous results of studies on drug interaction in man. III. Disulfiram and antipyrine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Quinine-induced alterations in drug disposition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Commentary: a physiological approach to hepatic drug clearance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Studies on the disposition of antipyrine, aminopyrine, and phenacetin using plasma, saliva, and urine.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Decreased theophylline half-life in cigarette smokers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Metabolism of debrisoquine sulphate in rat, dog and man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Interaction between antipyrine and aminopyrine.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Phenobarbitone-induced urinary excretions of D-glucaric acid and 6beta-hydroxycortisol in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Antipyrine: radioimmunoassay in plasma and saliva following administration of a high dose and a low dose

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Phenacetin metabolism: effect of hydrocarbons and cigarette smoking

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Disposition of aminopyrine, antipyrine, diazepam, and indocyanine green in patients with liver disease or on anticonvulsant drug therapy: diazepam breath test and correlations in drug elimination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Effect of vitamin C supplement on antipyrine disposition in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Induction of hepatic microsomal enzymes after brief administration of rifampicin in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Multiple molecular forms of catechol-O-methyltransferase. Evidence for two distinct forms, and their purification and physical characterization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

A direct radioimmunoassay for 6 beta-hydroxycortisol in human urine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

The features of hepatic enzyme induction with glutethimide in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Time-course of interaction between carbamazepine and clonazepam in normal man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Effects of an oral contraceptive on hepatic size and antipyrine metabolism in premenopausal women

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Interindividual and interspecies variation in the metabolism of the hallucinogen 4-methoxyamphetamine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

On the metabolism of antipyrine (phenazone) in man (author's transl)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Polymorphisms and deficient drug metabolism as triggers of toxic reactions (author's transl)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Oxidation phenotype and metiamide metabolism [proceedings]

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Application of the phenotyped panel approach to the detection of polymorphism of drug oxidation in man [proceedings]

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Drug metabolism in liver disease: Activity of hepatic microsomal metabolizing enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Assay of Antipyrine and Its Primary Metabolites in Plasma, Saliva and Urine by High-Performance Liquid Chromatography and Some Preliminary Results in Man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

7 July 2018

Phenol sulfotransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Stereoselectivity of differential routes of drug metabolism: the fate of the enantiomers of [14C]mephenytoin in the dog

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Multiplicity of mammalian microsomal cytochromes P-45

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

The metabolism of [14C]-debrisoquine in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

6-hydroxylation of cortisol and urinary 6β-hydroxycortisol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Genetic and environmental factors affecting drug disposition in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Factors influencing antipyrine elimination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Metabolism of debrisoquine sulfate. Identification of some urinary metabolites in rat and man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Effect of glucocorticoids and ACTH on antipyrine clearance in children

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Rate of drug metabolism in man measured by14CO2-breath analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

The antipyrine test in clinical pharmacology: Conceptions and misconceptions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Cimetidine: interaction with oral anticoagulants in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Polymorphic hydroxylation of Debrisoquine in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

The effect of enzyme induction on diazepam metabolism in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Genetic evidence for the involvement of different oxidative mechanisms in drug oxidation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

The effect of rifampicin on norethisterone pharmacokinetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Measurement of urinary 6-?-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Comparison and characterization of mammalian xenobiotic ketone reductases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

In vivo evaluation of Michaelis-Menten constants of hepatic drug-eliminating systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Evaluation ofin vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

Simplified method for determining acetylator phenotype.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1427483

AN EFFECT OF O,P'-DDD ON THE EXTRA-ADRENAL METABOLISM OF CORTISOL IN MAN.

28 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Kinetic discrimination of three sulfamethazine acetylation phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Urinary D-glucaric acid excretion and plasma antipyrine kinetics during enzyme induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Increased Hepatic Microsomal Enzyme Activity from Occupational Exposure to Certain Organochlorine Pesticides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Effect of environmental factors on drug metabolism: Decreased plasma half-life of antipyrine in workers exposed to chlorinated hydrocarbon insecticides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Defective metabolism of metoprolol in poor hydroxylators of debrisoquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Metabolism of d-glucuronolactone in mammalian systems. Identification of d-glucaric acid as a normal constituent of urine

21 January 2018

1 reference

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Genetic Control of Drug Levels in Man: Antipyrine

21 January 2018

1 reference

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THE ROLE OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN THE INTERNAL DISEASES CLINIC

21 January 2018

1 reference

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Clinical pharmacology: plasma protein binding of drugs

27 October 2018

1 reference

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Cigarette smoke: Stimulatory effect on metabolism of 3,4-benzpyrene by enzymes in rat lung

27 October 2018

1 reference

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Polymorphic oxidation of sparteine and debrisoquine: Related pharmacogenetic entities

27 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Influence of oral contraceptives of differing dosages on α-1-antitrypsin, γ-glutamyltransferase and alkaline phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Stereochemical heterogeneity of hepatic UDP-glucuronosyltransferase activity in rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1982.TB04950.X

Localization of gamma-glutamyltransferase in subcellular fractions of rat and rabbit liver: Effect of phenobarbital

21 January 2018

1 reference

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Effect of imipramine on hepatic gamma-glutamyltransferase in female rats. Interaction with contraceptives

21 January 2018

1 reference

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Blood Levels of Drug at the Equilibrium State after Multiple Dosing

21 January 2018

1 reference

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Rat and human liver microsomal epoxide hydratase. Purification and evidence for the existence of multiple forms

21 January 2018

1 reference

12 December 2020

Antibacterial activity in serum and urine following oral administration in man of DL473 (a cyclopentyl derivative of rifampicin) [proceedings]

1 reference

12 December 2020

6beta-Hydroxycortisol and other polar corticosteroids: measurement and significance in human urine

1 reference

12 December 2020

Genetic and environmental factors affecting ethanol metabolism in man

1 reference

12 December 2020

Slow hydroxylation of nortriptyline and concomitant poor debrisoquine hydroxylation: clinical implications

1 reference

12 December 2020

The determination of 17,21-dihydroxy-20-ketosteroids in urine and plasma

1 reference

12 December 2020

Polymorphism of carbon oxidation of drugs and clinical implications

1 reference

12 December 2020

Absence of seasonal variation in antipyrine metabolism

1 reference

12 December 2020

High plasma concentrations of beta-receptor blocking drugs and deficient debrisoquine hydroxylation

1 reference

12 December 2020

Kinetics of CO2-HCO3 minus in normal adult males

1 reference

12 December 2020

Aminopyrine N-demethylation: a prognostic test of liver function in patients with alcoholic liver disease

1 reference

12 December 2020

Norphenazone, a new metabolite of phenazone in human urine

1 reference

12 December 2020

Effect of intensive occupational exposure to DDT on phenylbutazone and cortisol metabolism in human subiects

1 reference

12 December 2020

Altered plasma half-lives of antipyrine, propylthiouracil, and methimazole in thyroid dysfunction

1 reference

12 December 2020

Effect of diphenylhydantoin on hepatic drug hydroxylation

1 reference

12 December 2020

E- and Z-10-hydroxylation of nortriptyline: relationship to polymorphic debrisoquine hydroxylation

1 reference

12 December 2020

Expiratory measurement of maximal amino-pyrine demethylation in vivo: effect of phenobarbital, partial hepatectomy, protacaval shunt and bile duct ligation in the rat

1 reference

12 December 2020

Genetically determined impaired drug sulphoxidation

1 reference

12 December 2020

Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis

1 reference

12 December 2020

A kinetic photometric method for serum gamma-glutamyl transpeptidase

1 reference

12 December 2020

Distinctive patterns of amobarbital metabolites

1 reference

12 December 2020

Metabolism of isoniazid in man as related to the occurrence of peripheral neuritis

1 reference

12 December 2020

Stimulatory effect of brussels sprouts and cabbage on human drug metabolism

1 reference

12 December 2020

Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man

1 reference

12 December 2020

Assessment of the cytochrome P-448 dependent liver enzyme system by a caffeine breath test

1 reference

12 December 2020

Disposition and oxidative metabolism of phenylbutazone in man

1 reference

12 December 2020

Beta-blockers and debrisoquine metaboliser status

1 reference

12 December 2020

Gas chromatographic assessment of the reproducibility of phenazone plasma half-life in young healthy volunteers

1 reference

12 December 2020

Liver Function in Workers Having High Tissue Stores of Chlorinated Hydrocarbon Pesticides

1 reference

12 December 2020

Aminopyrine disposition: studies on breath, saliva, and urine of normal subjects and patients with liver disease

1 reference

12 December 2020

The measurement, excretion, and source of urinary 6-hydroxycortisol in humans

1 reference

12 December 2020

Ethanol and antipyrine clearance

1 reference

12 December 2020

The effect of 3-methylcholanthrene on urinary 6 beta-hydroxycortisol excretion and hepatic enzyme activity in the marmoset monkey (Callithrix jacchus)

1 reference

12 December 2020

Impairment of drug metabolism in man by allopurinol and nortriptyline

1 reference

12 December 2020

Quantitative determination by HPLC of urinary 6?-hydroxycortisol, an indicator of enzyme induction by rifampicin and antiepileptic drugs

1 reference

12 December 2020

Debrisoquin hydroxylation polymorphism among Ghanaians and Caucasians

1 reference

12 December 2020

Toxicological implications of polymorphic drug metabolism

1 reference

12 December 2020

The metabolic fate of tolbutamide in man and in the rat

1 reference

12 December 2020

SULPHAPHENAZOLE-INDUCED HYPOGLYCAEMIC ATTACKS IN TOLBUTAMIDE-TREATED DIABETICS

1 reference

12 December 2020

Dose-dependent enzyme induction

1 reference

12 December 2020

Diphenylhydantoin intoxication. A complication of isoniazid therapy

1 reference

12 December 2020

Genetic impairment of phenformin metabolism

1 reference

12 December 2020

Genetic control of isoniazid metabolism in man

1 reference

12 December 2020

Drug induced lupus-like syndrome. Clinical and laboratory syndrome similar to systemic lupus erythematosus following antituberculous therapy: report of a case

1 reference

12 December 2020

Pharmacogenetics of tolbutamide metabolism in humans

1 reference

12 December 2020

Correlations between cytochrome P-450 and oxidative metabolism of benzo[a]pyrene and 7-ethoxycoumarin in human liver in vitro and antipyrine elimination in vivo

1 reference

12 December 2020

Effects of delta-9-tetrahydrocannabinol on drug distribution and metabolism. Antipyrine, pentobarbital, and ethanol

1 reference

12 December 2020

Drug Interactions with Warfarin: Studies with Dichloralphenazone, Chloral Hydrate and Phenazone (Antipyrine)

1 reference

12 December 2020

PHENOBARBITAL-INDUCED INCREASE IN 6-BETA-HYDROXYCORTISOL EXCRETION: CLUE TO ITS SIGNIFICANCE IN HUMAN URINE

1 reference

12 December 2020

Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydrazine metabolites

1 reference

12 December 2020

Effect of phenobarbital on the distribution of gamma-glutamyltransferase between hepatocytes and nonparenchymal cells in the rat

1 reference

12 December 2020

Quantitative Assessment of Hepatic Function by Breath Analysis after Oral Administration of [^14C]aminopyrine

1 reference

12 December 2020

Metabolism of Drugs. LXX. Further Study on Antipyrine Metabolism

1 reference

12 December 2020

Elimination of antipyrine from saliva as a measure of metabolism in man

1 reference

12 December 2020

Multiple, immunoidentical forms of phenobarbital-induced rat liver cytochromes P-450 are encoded by different mRNAs

1 reference

12 December 2020

Amobarbital--a probe of hepatic drug oxidation in man

1 reference

12 December 2020

The fate of antipyrine in man

1 reference

12 December 2020

Deficient metabolism of debrisoquine and sparteine

1 reference

12 December 2020

Antipyrine metabolism in man: influence of age, alcohol, caffeine, and smoking

1 reference

12 December 2020

Influence of the Genetically Controlled Deficiency in Debrisoquine Hydroxylation on Antipyrine Metabolite Formation

1 reference

12 December 2020

Effect of N-phenylbarbital (phetharbital) on the metabolism of testosterone and cortisol in man

1 reference

12 December 2020

Correlation of the plasma elimination of antipyrine and the appearance of 4-hydroxy antipyrine in the urine of man

1 reference

12 December 2020

Serum bilirubin and hepatic enzyme induction

1 reference

12 December 2020

Influence of liver disease and environmental factors on hepatic monooxygenase activity in vitro

1 reference

12 December 2020

A soluble form of gamma-glutamyl transpeptidase in human tissues

1 reference

12 December 2020

Enzyme changes in experimental biliary obstruction

1 reference

12 December 2020

Failure of hydrocortisone to alter acutely antipyrine disposition

1 reference

12 December 2020

HUMAN ACETYLATION POLYMORPHISM

1 reference

12 December 2020

The Estimation of 6β-Hydroxycortisol in Urine — A Comparison of Two Methods: High Performance Liquid Chromatography and Radioimmunoassay

1 reference

12 December 2020

Enhanced drug metabolism in cigarette smokers

1 reference

12 December 2020

Effect of charcoal-broiled beef on phenacetin metabolism in man

1 reference

12 December 2020

Urinary D-glucaric acid. An index of heparin microsomal enzyme activity in human females

1 reference

12 December 2020

Phenformin-induced lacticacidosis associated with impaired debrisoquine hydroxylation

1 reference

12 December 2020

Induction of drug metabolism in man after rifampicin treatment measured by increased hexobarbital and tolbutamide clearance

1 reference

12 December 2020

The effects of phenobarbitone on urinary 6 beta-hydroxycortisol excretion and hepatic enzyme activity in the marmoset monkey (Callithrix jacchus)

1 reference

12 December 2020

Serum γ-glutamyl transpeptidase activity in alcoholism

1 reference

12 December 2020

Effect of charcoal-broiled beef on antipyrine and theophylline metabolism

1 reference

12 December 2020

6 beta-Hydroxycortisol--a new steroid in human urine

1 reference

12 December 2020

Metabolism of 2-alpha- and 6-beta-hydroxycortisol in man: determination of production rates of 6-beta-hydroxycortisol with and without phenobarbital administration

1 reference

12 December 2020

Enzyme induction by oral testosterone

1 reference

12 December 2020

Purification and properties of N-acetyltransferase from mammalian liver

1 reference

12 December 2020

Influence of DH/DL alleles regulating debrisoquine oxidation on phenytoin hydroxylation

1 reference

12 December 2020

Plasma bombesin concentrations in patients with extensive small cell carcinoma of the lung

1 reference

12 December 2020

10.1111/J.1365-2125.1982.TB04950.X

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference

PubMed ID

6128018