Novel Ras antagonist blocks human melanoma growth (Q34505870)

2 August 2017

Novel Ras antagonist blocks human melanoma growth (English)

1 reference

2 August 2017

B Jansen

1

1 reference

2 August 2017

H Schlagbauer-Wadl

2

1 reference

2 August 2017

H Kahr

3

1 reference

2 August 2017

E Heere-Ress

4

1 reference

2 August 2017

B X Mayer

5

1 reference

2 August 2017

H Eichler

6

1 reference

2 August 2017

H Pehamberger

7

1 reference

2 August 2017

M Gana-Weisz

8

1 reference

2 August 2017

E Ben-David

9

1 reference

2 August 2017

Y Kloog

10

1 reference

2 August 2017

K Wolff

11

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 November 1999

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

96

1 reference

2 August 2017

24

1 reference

2 August 2017

14019-14024

1 reference

Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Growth inhibition of ras-dependent tumors in nude mice by a potent ras-dislodging antagonist

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Stringent structural requirements for anti-Ras activity of S-prenyl analogues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Dislodgment and accelerated degradation of Ras.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Protein tyrosine kinases and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

The Ras antagonist S-farnesylthiosalicylic acid induces inhibition of MAPK activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Functional rafts in cell membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Rho family GTPases: the cytoskeleton and beyond

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Function and regulation of ras.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Proteins regulating Ras and its relatives

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

The Ras signal transduction pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

ras oncogene activation does not induce sensitivity to natural killer cell-mediated lysis in human melanoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

How MAP kinases are regulated

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Ras CAAX peptidomimetic FTI 276 selectively blocks tumor growth in nude mice of a human lung carcinoma with K-Ras mutation and p53 deletion.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Transforming ras genes from human melanoma: a manifestation of tumour heterogeneity?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Production of transforming growth factor alpha in human pancreatic cancer cells: evidence for a superagonist autocrine cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Basic fibroblast growth factor in human melanoma.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Protein prenylation: more than just glue?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Triggering signaling cascades by receptor tyrosine kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

Direct demonstration of geranylgeranylation and farnesylation of Ki-Ras in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=24183

Ras mutations in human melanoma: a marker of malignant progression

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

Analysis of N-ras mutations in human cutaneous melanoma: tumor heterogeneity detected by polymerase chain reaction/single-stranded conformation polymorphism analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

Unexpectedly strong binding of a large metal ion (Bi3+) to human serum transferrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.24.14019

Activated N-ras contributes to the chemoresistance of human melanoma in severe combined immunodeficiency (SCID) mice by blocking apoptosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10570191

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ras mutations in human melanotic lesions: K-ras activation is a frequent and early event in melanoma development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10570191

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.96.24.14019

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference