A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice (Q34503382)

2 August 2017

title

A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice (English)

1 reference

2 August 2017

Anne S. Henkel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

1 September 2024

Kristy A. Anderson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

1 September 2024

Amanda M. Dewey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

1 September 2024

Mark H. Kavesh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

1 September 2024

Richard M. Green

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

1 September 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21097822

1 September 2024

publication date

20 November 2010

1 reference

full work available at URL

2 August 2017

http://www.jlr.org/article/S0022227520405243/pdf

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

http://www.jlr.org/cgi/content/full/52/2/289

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

http://www.jlr.org/cgi/content/abstract/52/2/289

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

http://www.jlr.org/cgi/reprint/52/2/289.pdf

1 September 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

https://europepmc.org/articles/PMC3023549

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

https://europepmc.org/articles/PMC3023549?pdf=render

1 September 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

https://doi.org/10.1194/jlr.m012781

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097822

Journal of Lipid Research

1 September 2024

published in

1 reference

2 August 2017

volume

52

1 reference

2 August 2017

issue

2

1 reference

2 August 2017

page(s)

289-298

1 reference

Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha

2 August 2017

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7 July 2018

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7 July 2018

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Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine

7 July 2018

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Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells

7 July 2018

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Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

7 July 2018

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Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells

7 July 2018

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Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice

7 July 2018

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The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK.

7 July 2018

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Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.

7 July 2018

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7 July 2018

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Cholesterol feeding of mice expressing cholesterol 7alpha-hydroxylase increases bile acid pool size despite decreased enzyme activity

7 July 2018

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Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

7 July 2018

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The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis

7 July 2018

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

7 July 2018

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

7 July 2018

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Hepatocyte nuclear factor 1 binds to and transactivates the human but not the rat CYP7A1 promoter

7 July 2018

1 reference

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

7 July 2018

1 reference

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Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

7 July 2018

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Differential roles of extracellular signal-regulated kinase-1/2 and p38(MAPK) in interleukin-1beta- and tumor necrosis factor-alpha-induced low density lipoprotein receptor expression in HepG2 cells

7 July 2018

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Endotoxin, TNF, and IL-1 decrease cholesterol 7 alpha-hydroxylase mRNA levels and activity

7 July 2018

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

7 July 2018

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

7 July 2018

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Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeys

7 July 2018

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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

7 July 2018

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Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

21 January 2018

1 reference

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Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis

21 January 2018

1 reference

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Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet

21 January 2018

1 reference

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The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

21 January 2018

1 reference

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Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

21 January 2018

1 reference

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Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis

21 January 2018

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Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle

21 January 2018

1 reference

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Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes

21 January 2018

1 reference

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Interleukin 1 and tumor necrosis factor activate common multiple protein kinases in human fibroblasts

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21097822

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of classic and alternative bile acid synthesis in hypercholesterolemic rabbits: effects of cholesterol feeding and bile acid depletion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21097822

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21097822

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M012781

1 reference

2 August 2017

1 reference

2 August 2017

1 reference