Interactions between MHC molecules and co-receptors of the TCR. (Q34493030)

2 August 2017

1 reference

title

Interactions between MHC molecules and co-receptors of the TCR. (English)

1 reference

2 August 2017

Rolf König

1

1 reference

PubMed ID

11790535

2 August 2017

language of work or name

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1 February 2002

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Current Opinion in Immunology

2 August 2017

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2 August 2017

14

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2 August 2017

75-83

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2 August 2017

1

1 reference

MHC recognition in thymic development: distinct, parallel pathways for survival and lineage commitment.

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Highly efficient selection of CD4 and CD8 lineage thymocytes supports an instructive model of lineage commitment

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Definition of the alpha 2 region of HLA-DR molecules involved in CD4 binding

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Coreceptor function of mutant human CD4 molecules without affinity to gp120 of human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Human CD4 residue Phe 43 is critical for repertoire development and maturation of MHC class II restricted CD4 single-positive T lineage cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Dimeric association and segmental variability in the structure of human CD4

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Oligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp120.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Direct evidence for native CD4 oligomers in lymphoid and monocytoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Synthetic peptides derived from the fourth domain of CD4 antagonize off function and inhibit T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Structures of an MHC class II molecule with covalently bound single peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Intracellular and cell surface heterotypic associations of human leukocyte antigen-DR and human invariant chain

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Detection of dimers of dimers of human leukocyte antigen (HLA)-DR on the surface of living cells by single-particle fluorescence imaging

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Ligand-specific oligomerization of T-cell receptor molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Amino acid substitutions in the putative MHC class II "dimer of dimers" interface inhibit CD4+ T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Mutations in MHC class II dimer of dimers contact residues: effects on antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Interaction between CD8 and major histocompatibility complex (MHC) class I mediated by multiple contact surfaces that include the alpha 2 and alpha 3 domains of MHC class I.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The role of charge and multiple faces of the CD8 alpha/alpha homodimer in binding to major histocompatibility complex class I molecules: support for a bivalent model

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Structural basis of cell-cell interactions in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The CD8 beta polypeptide is required for the recognition of an altered peptide ligand as an agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The CD8beta ectodomain contributes to the augmented coreceptor function of CD8alphabeta heterodimers relative to CD8alphaalpha homodimers

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The isolated major histocompatibility complex class I alpha3 domain binds beta2m and CD8alphaalpha dimers

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Expression, purification, and functional analysis of murine ectodomain fragments of CD8alphaalpha and CD8alphabeta dimers

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Peptide antagonism and T cell receptor interactions with peptide-MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the alpha 3 domain of MHC I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Co-engagement of CD8 with the T cell receptor is required for negative selection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

A differential-avidity model for T-cell selection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The crystal structure of a T cell receptor in complex with peptide and MHC class II

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Impaired survival of T helper cells in the absence of CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

How alpha beta T cells deal with induced TCR alpha ablation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The T cell receptor for antigen: signaling and ligand discrimination

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Dynamics of the immunological synapse: finding, establishing and solidifying a connection

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Differential clustering of CD4 and CD3zeta during T cell recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

CD4 augments the response of a T cell to agonist but not to antagonist ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2801%2900300-4

7 January 2021

10.1016/S0952-7915(01)00300-4

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11790535