Small-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold. (Q34488163)

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18 February 2020

title

Small-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold (English)

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18 February 2020

0 references

1

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18 February 2020

Daniel A Harki

series ordinal

4

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18 February 2020

3

Reuben S Harris

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18 February 2020

author name string

Ming Li

series ordinal

2

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18 February 2020

publication date

23 November 2012

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18 February 2020

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18 February 2020

volume

8

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18 February 2020

page(s)

112-117

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18 February 2020

issue

1

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SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor.

18 February 2020

cites work

1 reference

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Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication

6 July 2018

1 reference

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First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G

6 July 2018

1 reference

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Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1

6 July 2018

1 reference

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An anti-HIV-1 compound that increases steady-state expression of apoplipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G.

6 July 2018

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Synthesis of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of their antimicrobial activity

6 July 2018

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New non-hydroxamic ADAMTS-5 inhibitors based on the 1,2,4-triazole-3-thiol scaffold.

6 July 2018

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Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel

6 July 2018

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Antiretroviral therapy and management of HIV infection

6 July 2018

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APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis

6 July 2018

1 reference

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Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G

6 July 2018

1 reference

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Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces

6 July 2018

1 reference

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Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics

6 July 2018

1 reference

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Multiple ways of targeting APOBEC3-virion infectivity factor interactions for anti-HIV-1 drug development.

6 July 2018

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Twenty-six years of anti-HIV drug discovery: where do we stand and where do we go?

6 July 2018

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HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

6 July 2018

1 reference

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An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3786134

Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent

6 July 2018

1 reference

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APOBEC3G inhibits elongation of HIV-1 reverse transcripts

6 July 2018

1 reference

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Small-molecule inhibition of HIV-1 Vif.

6 July 2018

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HIV-1 accessory proteins--ensuring viral survival in a hostile environment

6 July 2018

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Cytidine deamination induced HIV-1 drug resistance

6 July 2018

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The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction

6 July 2018

1 reference

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Enzymatically active APOBEC3G is required for efficient inhibition of human immunodeficiency virus type 1.

6 July 2018

1 reference

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Zinc chelation inhibits HIV Vif activity and liberates antiviral function of the cytidine deaminase APOBEC3G.

6 July 2018

1 reference

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Human APOBEC3 proteins, retrovirus restriction, and HIV drug resistance.

6 July 2018

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Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation

6 July 2018

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Enhancing immunity to HIV through APOBEC.

6 July 2018

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Crossref

https://api.crossref.org/works/10.1002%2FCMDC.201200411

Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes of Schiff bases derived from fluorobenzaldehyde and triazoles.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1002%2FCMDC.201200411

Some bivalent metal complexes of Schiff bases containing N and S donor atoms.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1002%2FCMDC.201200411

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CMDC.201200411

1 reference

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18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23180603%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference