Engineered Biosynthesis of Gilvocarcin Analogues with Altered Deoxyhexopyranose Moieties (Q34487896)

2 August 2017

title

Engineered biosynthesis of gilvocarcin analogues with altered deoxyhexopyranose moieties (English)

1 reference

https://api.crossref.org/works/10.1128/AEM.01774-10

2 August 2017

Engineered Biosynthesis of Gilvocarcin Analogues with Altered Deoxyhexopyranose Moieties (English)

1 reference

26 August 2024

Carmen Méndez

3

0 references

author name string

Tao Liu

2

1 reference

2 August 2017

Jürgen Rohr

5

1 reference

2 August 2017

Micah D. Shepherd

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

26 August 2024

Jose A. Salas

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

26 August 2024

language of work or name

English

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publication date

12 November 2010

1 reference

full work available at URL

2 August 2017

https://aem.asm.org/content/aem/77/2/435.full.pdf

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

http://aem.asm.org/cgi/content/abstract/77/2/435

26 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21075894/pdf/?tool=EBI

26 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21075894/?tool=EBI

26 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

https://europepmc.org/articles/PMC3020532

26 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

https://europepmc.org/articles/PMC3020532?pdf=render

26 August 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

https://doi.org/10.1128/aem.01774-10

26 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21075894

https://journals.asm.org/doi/pdf/10.1128/AEM.01774-10

26 August 2024

1 reference

https://api.crossref.org/works/10.1128/AEM.01774-10

Applied and Environmental Microbiology

26 August 2024

published in

1 reference

2 August 2017

volume

77

1 reference

2 August 2017

issue

2

1 reference

2 August 2017

page(s)

435-441

1 reference

Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters

2 August 2017

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity

6 July 2018

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6 July 2018

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Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity

6 July 2018

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Structure of the yeast histone H3-ASF1 interaction: implications for chaperone mechanism, species-specific interactions, and epigenetics

6 July 2018

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Combinatorial biosynthesis of antitumor deoxysugar pathways in Streptomyces griseus: Reconstitution of "unnatural natural gene clusters" for the biosynthesis of four 2,6-D-dideoxyhexoses

6 July 2018

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Inactivation of gilGT, encoding a C-glycosyltransferase, and gilOIII, encoding a P450 enzyme, allows the details of the late biosynthetic pathway to gilvocarcin V to be delineated

6 July 2018

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Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase

6 July 2018

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Engineering biosynthetic pathways for deoxysugars: branched-chain sugar pathways and derivatives from the antitumor tetracenomycin.

6 July 2018

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The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins

6 July 2018

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An evolving hierarchical family classification for glycosyltransferases

6 July 2018

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Histone H3 and heat shock protein GRP78 are selectively cross-linked to DNA by photoactivated gilvocarcin V in human fibroblasts

6 July 2018

1 reference

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Evidence that the extracytoplasmic function sigma factor sigmaE is required for normal cell wall structure in Streptomyces coelicolor A3(2).

6 July 2018

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A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities

6 July 2018

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Photoactivated gilvocarcin V induces DNA-protein crosslinking in genes for human ribosomal RNA and dihydrofolate reductase

6 July 2018

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Antitumor agents from Streptomyces anandii: gilvocarcins V, M and E.

6 July 2018

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Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities

6 July 2018

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Ravidomycin (AY-25,545), a new antitumor antibiotic.

6 July 2018

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Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines

6 July 2018

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6 July 2018

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New antitumor substances, BE-12406A and BE-12406B, produced by a streptomycete. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties

6 July 2018

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Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

6 July 2018

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Gilvocarcin V exhibits both equilibrium DNA binding and UV light induced DNA adduct formation which is sequence context dependent

6 July 2018

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Engineering deoxysugar biosynthetic pathways from antibiotic-producing microorganisms. A tool to produce novel glycosylated bioactive compounds

6 July 2018

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The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A.

27 October 2018

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Activation of Antitumor Agent Gilvocarcins by Visible Light

27 October 2018

1 reference

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The photobiological differences of gilvocarcins V and M are not related to their transient intermediates and triplet yields

27 October 2018

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12 December 2020

New ravidomycin analogues, FE35A and FE35B, apoptosis inducers produced by Streptomyces rochei

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12 December 2020

Delineating the earliest steps of gilvocarcin biosynthesis: role of GilP and GilQ in starter unit specificity

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12 December 2020

Generation of hybrid elloramycin analogs by combinatorial biosynthesis using genes from anthracycline-type and macrolide biosynthetic pathways

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12 December 2020

Gilvocarcins, new antitumor antibiotics. 2. Structural elucidation

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12 December 2020

Photosensitized DNA breaks and DNA-to-protein crosslinks induced in human cells by antitumor agent gilvocarcin V

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12 December 2020

New antitumor substances, BE-12406A and BE-12406B, produced by a streptomycete. II. Structure determination

1 reference

12 December 2020

A comparative study of the visible light photochemistry of gilvocarcins V and M

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12 December 2020

https://api.crossref.org/works/10.1128/AEM.01774-10

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The Journal of Antibiotics

26 August 2024

38

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355

1983

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https://api.crossref.org/works/10.1128/AEM.01774-10

26 August 2024

Identifiers

DOI

10.1128/AEM.01774-10

1 reference

2 August 2017

1 reference

2 August 2017

1 reference