SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice (Q34478749)

2 August 2017

title

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice (English)

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Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

2 August 2017

corrigendum / erratum

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Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

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29

Guglielmo Roma

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2 August 2017

James Palacino

1

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2 August 2017

Susanne E Swalley

2

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2 August 2017

Cheng Song

3

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2 August 2017

Atwood K Cheung

4

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2 August 2017

Lei Shu

5

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2 August 2017

Xiaolu Zhang

6

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2 August 2017

Mailin Van Hoosear

7

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2 August 2017

Youngah Shin

8

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2 August 2017

Donovan N Chin

9

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2 August 2017

Caroline Gubser Keller

10

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2 August 2017

Martin Beibel

11

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2 August 2017

Nicole A Renaud

12

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2 August 2017

Thomas M Smith

13

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2 August 2017

Michael Salcius

14

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2 August 2017

Xiaoying Shi

15

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2 August 2017

Marc Hild

16

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2 August 2017

Rebecca Servais

17

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2 August 2017

Monish Jain

18

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2 August 2017

Lin Deng

19

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2 August 2017

Caroline Bullock

20

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2 August 2017

Michael McLellan

21

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2 August 2017

Sven Schuierer

22

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2 August 2017

Leo Murphy

23

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2 August 2017

Marcel J J Blommers

24

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2 August 2017

Cecile Blaustein

25

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2 August 2017

Frada Berenshteyn

26

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2 August 2017

Arnaud Lacoste

27

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2 August 2017

Jason R Thomas

28

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2 August 2017

Gregory A Michaud

30

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2 August 2017

Brian S Tseng

31

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2 August 2017

Jeffery A Porter

32

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2 August 2017

Vic E Myer

33

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2 August 2017

John A Tallarico

34

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2 August 2017

Lawrence G Hamann

35

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2 August 2017

Daniel Curtis

36

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2 August 2017

Mark C Fishman

37

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2 August 2017

William F Dietrich

38

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2 August 2017

Natalie A Dales

39

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2 August 2017

Rajeev Sivasankaran

40

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2 August 2017

publication date

1 June 2015

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2 August 2017

published in

Nature Chemical Biology

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2 August 2017

volume

11

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2 August 2017

issue

7

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2 August 2017

page(s)

511-517

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https://scigraph.springernature.com/pub.10.1038/nchembio.1837

2 August 2017

exact match

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cites work

Pan-ethnic carrier screening and prenatal diagnosis for spinal muscular atrophy: clinical laboratory analysis of >72,400 specimens

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

21 January 2018

Spinal muscular atrophy.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Targeting RNA-splicing for SMA treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Spinal muscular atrophy: a timely review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Spinal muscular atrophy: a deficiency in a ubiquitous protein; a motor neuron-specific disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Molecular mechanisms of spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

A day in the life of the spliceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Alternative isoform regulation in human tissue transcriptomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Splicing regulation: from a parts list of regulatory elements to an integrated splicing code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Antisense masking of an hnRNP A1/A2 intronic splicing silencer corrects SMN2 splicing in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Pick one, but be quick: 5' splice sites and the problems of too many choices

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

The alternative heart: impact of alternative splicing in heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

SpliceDisease database: linking RNA splicing and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Regulation of SMN protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Identification of a battery of tests for drug candidate evaluation in the SMNDelta7 neonate model of spinal muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Temporal requirement for high SMN expression in SMA mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Requirement of enhanced Survival Motoneuron protein imposed during neuromuscular junction maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Binding of DAZAP1 and hnRNPA1/A2 to an exonic splicing silencer in a natural BRCA1 exon 18 mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Modulating role of RNA structure in alternative splicing of a critical exon in the spinal muscular atrophy genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

WebLogo: A Sequence Logo Generator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

MEME SUITE: tools for motif discovery and searching

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

A computational approach for genome-wide mapping of splicing factor binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

SEC-TID: A Label-Free Method for Small-Molecule Target Identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Splicing factor SF3b as a target of the antitumor natural product pladienolide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

An in vivo reporter system for measuring increased inclusion of exon 7 in SMN2 mRNA: potential therapy of SMA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Fast gapped-read alignment with Bowtie 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Pre-mRNA splicing by complementation with purified human U1, U2, U4/U6 and U5 snRNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

ALiBERO: evolving a team of complementary pocket conformations rather than a single leader

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Biosensor Analysis of the Interaction between Immobilized Human Serum Albumin and Drug Compounds for Prediction of Human Serum Albumin Binding Levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1837

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

21 January 2018

1 reference

12 December 2020

SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

1 reference

12 December 2020

An efficient and reversible transposable system for gene delivery and lineage-specific differentiation in human embryonic stem cells

1 reference

12 December 2020

Detection of the survival motor neuron (SMN) genes by FISH: further evidence for a role for SMN2 in the modulation of disease severity in SMA patients

1 reference

12 December 2020

Differential SMN2 expression associated with SMA severity

1 reference

12 December 2020

Purification of U small nuclear ribonucleoprotein particles

1 reference

12 December 2020

The missing puzzle piece: splicing mutations

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.1837

1 reference

2 August 2017

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