Towards a rational development of anti-endotoxin agents: novel approaches to sequestration of bacterial endotoxins with small molecules (Q34470625)

2 August 2017

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title

Towards a rational development of anti-endotoxin agents: novel approaches to sequestration of bacterial endotoxins with small molecules (English)

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2 August 2017

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David SA

1

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2 August 2017

1 November 2001

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Journal of Molecular Recognition

2 August 2017

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2 August 2017

14

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2 August 2017

6

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2 August 2017

370-387

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Treatment of sepsis by extracorporeal elimination of endotoxin using polymyxin B-immobilized fiber

2 August 2017

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Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor alpha and interleukin 6. Comparison of O side chain-specific antibodies with core LPS antibodies

21 January 2018

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Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution

21 January 2018

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The BPI/LBP family of proteins: a structural analysis of conserved regions

21 January 2018

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Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy

21 January 2018

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Tlr4: central component of the sole mammalian LPS sensor

21 January 2018

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Regulation of an essential innate immune response by the p50 subunit of NF-kappaB.

21 January 2018

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Gram-negative sepsis: a dilemma of modern medicine

21 January 2018

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Purification, toxicity, and antiendotoxin activity of polymyxin B nonapeptide

21 January 2018

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Interaction of melittin with endotoxic lipid A.

21 January 2018

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Effect of sialylation of lipopolysaccharide of Neisseria gonorrhoeae on recognition and complement-mediated killing by monoclonal antibodies directed against different outer-membrane antigens.

21 January 2018

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Effect of pH on solubility and ionic state of lipopolysaccharide obtained from the deep rough mutant of Escherichia coli.

21 January 2018

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Crystal structure of a pentamidine-oligonucleotide complex: implications for DNA-binding properties

21 January 2018

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The helical hydrophobic moment: a measure of the amphiphilicity of a helix

21 January 2018

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The hydrophobic moment detects periodicity in protein hydrophobicity

21 January 2018

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Protective effects of a recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in an animal model of gram-negative sepsis.

21 January 2018

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Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

21 January 2018

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

21 January 2018

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Highly Substitutedter-Cyclopentanes as Receptors for Lipid A

21 January 2018

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CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide

21 January 2018

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Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.

21 January 2018

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Influence of synthetic antiendotoxin peptides on lipopolysaccharide (LPS) recognition and LPS-induced proinflammatory cytokine responses by cells expressing membrane-bound CD14

21 January 2018

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Functional activities of monoclonal antibodies to the O side chain of Escherichia coli lipopolysaccharides in vitro and in vivo

21 January 2018

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Comparison of a recombinant endotoxin-neutralizing protein with a human monoclonal antibody to endotoxin for the treatment of Escherichia coli sepsis in rats.

21 January 2018

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Antibodies against CD14 protect primates from endotoxin-induced shock

21 January 2018

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Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

21 January 2018

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21 January 2018

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Gemini surfactants: a new class of self-assembling molecules

21 January 2018

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Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides

21 January 2018

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Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans

21 January 2018

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Direct gene transfer for treatment of human cancer

21 January 2018

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Antiendotoxin strategies for the prevention and treatment of septic shock. New approaches and future directions

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

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Structural basis of endotoxin recognition by natural polypeptides

21 January 2018

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Solution structure of polymyxins B and E and effect of binding to lipopolysaccharide: an NMR and molecular modeling study.

21 January 2018

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Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.

21 January 2018

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A critical role for monocytes and CD14 in endotoxin-induced endothelial cell activation

21 January 2018

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A controlled trial of HA-1A in a canine model of gram-negative septic shock.

21 January 2018

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The chemical structure of bacterial endotoxin in relation to bioactivity

21 January 2018

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Polycation binding to isolated lipopolysaccharide from antibiotic-hypersusceptible mutant strains of Escherichia coli

21 January 2018

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Gut barrier function and the surgeon.

21 January 2018

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Use of helical wheels to represent the structures of proteins and to identify segments with helical potential

21 January 2018

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Anti-CD14 mAb treatment provides therapeutic benefit after in vivo exposure to endotoxin

21 January 2018

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Structure and function of lipopolysaccharide binding protein

21 January 2018

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The role of CD14 and lipopolysaccharide-binding protein (LBP) in the activation of different cell types by endotoxin

21 January 2018

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Cutting edge: cationic antimicrobial peptides block the binding of lipopolysaccharide (LPS) to LPS binding protein

21 January 2018

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21 January 2018

Antiendotoxin antibodies

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Titration calorimetric studies to elucidate the specificity of the interactions of polymyxin B with lipopolysaccharides and lipid A.

21 January 2018

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Polymyxin B prevents lipopolysaccharide-induced release of tumor necrosis factor-alpha from alveolar macrophages.

21 January 2018

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Polymyxin and Related Peptide Antibiotics

21 January 2018

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Surface plasmon resonance studies resolve the enigmatic endotoxin neutralizing activity of polymyxin B.

21 January 2018

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Participation of lipopolysaccharide-binding protein in lipopolysaccharide-dependent macrophage activation

21 January 2018

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Starburst Dendrimers: Molecular-Level Control of Size, Shape, Surface Chemistry, Topology, and Flexibility from Atoms to Macroscopic Matter

21 January 2018

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Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin

21 January 2018

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Recognition of gram-negative bacteria and endotoxin by the innate immune system

21 January 2018

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Sensitization of Gram-negative bacteria to antibiotics and complement by a nontoxic oligopeptide.

21 January 2018

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Polycations as outer membrane-disorganizing agents

21 January 2018

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Effective inhibition of cardiolipin-binding antibodies in gram-negative infections by bacterial lipopolysaccharide

21 January 2018

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Assessment of ability of murine and human anti-lipid A monoclonal antibodies to bind and neutralize lipopolysaccharide

21 January 2018

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Catalytic properties of lipopolysaccharide (LPS) binding protein. Transfer of LPS to soluble CD14.

21 January 2018

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Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JMR.549

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2 August 2017

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PubMed ID

11757070