Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression (Q34467878)

2 August 2017

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression (English)

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2 August 2017

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Melcher A

1

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2 August 2017

Todryk S

2

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2 August 2017

Hardwick N

3

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2 August 2017

Ford M

4

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2 August 2017

Jacobson M

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2 August 2017

Vile RG

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2 August 2017

language of work or name

English

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publication date

1 May 1998

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2 August 2017

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2 August 2017

4

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2 August 2017

581-587

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2 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/nm0598-581

2 August 2017

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Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy

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Structure and expression of an inducible HSP70-encoding gene from Mus musculus

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Gene therapy of hepatoma: bystander effects and non-apoptotic cell death induced by thymidine kinase and ganciclovir

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Priming of T cells by heat shock protein-peptide complexes as the basis of tumor vaccines

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In vivo gene therapy of malignant tumours with heat shock protein-65 gene

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Cancer antigens: immune recognition of self and altered self

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Can co-stimulated tumor immunity be therapeutically efficacious?

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Immunotherapy III: Combinatorial molecular immunotherapy--a synthesis and suggestions

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Immune system in suicide-gene therapy

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Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

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A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides

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Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations

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Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors

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Regression of established macroscopic liver metastases after in situ transduction of a suicide gene

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Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression

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A family of bicistronic vectors to enhance both local and systemic antitumor effects of HSVtk or cytokine expression in a murine melanoma model

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Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination

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Cell death: current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo.

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Cellular requirements for tumor-specific immunity elicited by heat shock proteins: tumor rejection antigen gp96 primes CD8+ T cells in vivo

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Tumor cells transfected with a bacterial heat-shock gene lose tumorigenicity and induce protection against tumors

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7 January 2021

Apoptosis in cancer therapy: crossing the threshold

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7 January 2021

Identifiers

DOI

10.1038/NM0598-581

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Dimensions Publication ID

2 August 2017

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1 reference