Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. (Q34462811)

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8 January 2020

title

Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation (English)

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8 January 2020

6

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author name string

Isabelle Weinhofer

1

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8 January 2020

Markus Kunze

2

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8 January 2020

Heidelinde Rampler

3

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8 January 2020

Angie L Bookout

4

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8 January 2020

Sonja Forss-Petter

5

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language of work or name

English

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publication date

24 October 2005

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Journal of Biological Chemistry

8 January 2020

published in

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volume

280

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issue

50

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8 January 2020

page(s)

41243-41251

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Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy

8 January 2020

cites work

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Gene redundancy and pharmacological gene therapy: implications for X-linked adrenoleukodystrophy.

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Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

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Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice

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Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism

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A mouse model for X-linked adrenoleukodystrophy

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Thyroid hormone induction of the adrenoleukodystrophy-related gene (ABCD2).

21 January 2018

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Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

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LuXuRies of lipid homeostasis: the unity of nuclear hormone receptors, transcription regulation, and cholesterol sensing

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Liver X receptors interact with corepressors to regulate gene expression

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Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages

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Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.

21 January 2018

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Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha

21 January 2018

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

21 January 2018

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The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression.

21 January 2018

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Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants

21 January 2018

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Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

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Evaluation of the therapeutic potential of PPARalpha agonists for X-linked adrenoleukodystrophy.

21 January 2018

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Liver X Receptor Signaling Pathways in Cardiovascular Disease

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Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2

21 January 2018

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Differential nuclear receptor signalling from DR4-type response elements

21 January 2018

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Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

21 January 2018

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Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2).

21 January 2018

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T0901317 is a dual LXR/FXR agonist

21 January 2018

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CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor

21 January 2018

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Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy

21 January 2018

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Characterization of the Adrenoleukodystrophy-Related (ALDR, ABCD2) Gene Promoter: Inductibility by Retinoic Acid and Forskolin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M509450200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16249184%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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