Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen (Q34462136)

2 August 2017

title

Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen (English)

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2 August 2017

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6

Patrick T Ellinor

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2 August 2017

David S Peal

1

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2 August 2017

Robert W Mills

2

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2 August 2017

Stacey N Lynch

3

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2 August 2017

Janet M Mosley

4

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2 August 2017

Evi Lim

5

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2 August 2017

Craig T January

7

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2 August 2017

Randall T Peterson

8

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2 August 2017

David J Milan

9

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2 August 2017

language of work or name

English

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publication date

15 November 2010

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2 August 2017

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2 August 2017

volume

123

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2 August 2017

issue

1

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2 August 2017

page(s)

23-30

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Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization

2 August 2017

cites work

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Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives

6 July 2018

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Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome

6 July 2018

1 reference

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Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutation

6 July 2018

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G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences

6 July 2018

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Zebrafish model for human long QT syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3015011

Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism

6 July 2018

1 reference

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Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome

6 July 2018

1 reference

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Drug-induced prolongation of the QT interval

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3015011

Long QT syndrome in neonates: conduction disorders associated with HERG mutations and sinus bradycardia with KCNQ1 mutations

6 July 2018

1 reference

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The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3015011

Molecular and cellular mechanisms of cardiac arrhythmias

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3015011

Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.

6 July 2018

1 reference

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Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

6 July 2018

1 reference

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SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

6 July 2018

1 reference

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A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

6 July 2018

1 reference

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Genetics and molecular biology of the inherited long QT syndrome

6 July 2018

1 reference

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Infants with long-QT syndrome and 2:1 atrioventricular block

6 July 2018

1 reference

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Unraveling tissue regeneration pathways using chemical genetics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3015011

Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3015011

Drugs that induce repolarization abnormalities cause bradycardia in zebrafish

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3015011

Two:one atrioventricular block in infants with congenital long QT syndrome

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21098441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1161/CIRCULATIONAHA.110.003731

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2 August 2017

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2 August 2017

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