The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases (Q34450011)

2 August 2017

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title

The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases (English)

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2 August 2017

A Sanjay

1

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2 August 2017

W C Horne

series ordinal

2

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2 August 2017

R Baron

series ordinal

3

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2 August 2017

language of work or name

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27 November 2001

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Science's STKE : signal transduction knowledge environment

2 August 2017

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2 August 2017

2001

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2 August 2017

110

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2 August 2017

pe40

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Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

2 August 2017

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Themes and variations on ubiquitylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

The ubiquitin-proteasome pathway: on protein death and cell life

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Cbl: many adaptations to regulate protein tyrosine kinases

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

cbl-b inhibits epidermal growth factor receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

D-cbl, a negative regulator of the Egfr pathway, is required for dorsoventral patterning in Drosophila oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

The linker phosphorylation site Tyr292 mediates the negative regulatory effect of Cbl on ZAP-70 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex

21 January 2018

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https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.110.PE40

10.1126/STKE.2001.110.PE40

21 January 2018

Identifiers

DOI

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2 August 2017

1 reference