Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro (Q34445108)

2 August 2017

Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro (English)

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2 August 2017

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Li-jing Yang

1

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2 August 2017

Yan Chen

2

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2 August 2017

Jing He

3

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2 August 2017

Sha Yi

4

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2 August 2017

Lu Wen

5

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2 August 2017

Jie Zhao

6

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2 August 2017

Ben-ping Zhang

7

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2 August 2017

Guo-hui Cui

8

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2 August 2017

15 October 2012

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Acta Pharmacologica Sinica

2 August 2017

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2 August 2017

33

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2 August 2017

12

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2 August 2017

1542-1548

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https://scigraph.springernature.com/pub.10.1038/aps.2012.102

2 August 2017

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cites work

Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1

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The time-dependent autophagy protects against apoptosis with possible involvement of Sirt1 protein in multiple myeloma under nutrient depletion

6 July 2018

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Betulinic acid delivered in liposomes reduces growth of human lung and colon cancers in mice without causing systemic toxicity

6 July 2018

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Autophagy is a therapeutic target in anticancer drug resistance.

6 July 2018

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Methods in mammalian autophagy research

6 July 2018

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Betulinic acid, a natural compound with potent anticancer effects

6 July 2018

1 reference

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Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Effect of betulinic acid on inducing apoptosis of human multiple myeloma cell line RPMI-8226

6 July 2018

1 reference

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Targeting mitochondrial apoptosis by betulinic acid in human cancers

6 July 2018

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Effect of autophagy on multiple myeloma cell viability

6 July 2018

1 reference

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Peltophorum africanum, a traditional South African medicinal plant, contains an anti HIV-1 constituent, betulinic acid

6 July 2018

1 reference

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Autophagy fights disease through cellular self-digestion

6 July 2018

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

6 July 2018

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Effect of betulinic acid on anticancer drug-resistant colon cancer cells

6 July 2018

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Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors

6 July 2018

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Betulinic acid decreases expression of bcl-2 and cyclin D1, inhibits proliferation, migration and induces apoptosis in cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Inhibition of macroautophagy triggers apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Betulinic acid-induced apoptosis in leukemia cells

6 July 2018

1 reference

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Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Effects of betulinic acid alone and in combination with irradiation in human melanoma cells

6 July 2018

1 reference

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Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.102

Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.102

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.102

DAMP-mediated autophagy contributes to drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.102

Clinical roundtable monograph. Emerging treatment options for relapsed and refractory multiple myeloma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4001834

Emerging therapies for multiple myeloma

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23064721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of autophagy in anticancer therapy: promises and uncertainties

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23064721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/APS.2012.102

1 reference

Dimensions Publication ID

2 August 2017

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1 reference

2 August 2017

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