Development of a minimal saponin vaccine adjuvant based on QS-21 (Q34433407)

2 August 2017

Development of a minimal saponin vaccine adjuvant based on QS-21 (English)

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2 August 2017

Alberto Fernández-Tejada

1

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2 August 2017

Eric K Chea

2

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2 August 2017

Constantine George

3

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2 August 2017

NagaVaraKishore Pillarsetty

4

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2 August 2017

Jeffrey R Gardner

5

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2 August 2017

Philip O Livingston

6

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2 August 2017

Govind Ragupathi

7

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2 August 2017

Jason S Lewis

8

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2 August 2017

Derek S Tan

9

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2 August 2017

David Y Gin

10

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2 August 2017

1 June 2014

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2 August 2017

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2 August 2017

6

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2 August 2017

7

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2 August 2017

635-643

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https://scigraph.springernature.com/pub.10.1038/nchem.1963

2 August 2017

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cites work

Modern subunit vaccines: development, components, and research opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Unmet needs in modern vaccinology: adjuvants to improve the immune response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Design and synthesis of potent Quillaja saponin vaccine adjuvants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

New horizons in adjuvants for vaccine development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

The safety and tolerability of an HIV-1 DNA prime-protein boost vaccine (DP6-001) in healthy adult volunteers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Divergent immunoglobulin g subclass activity through selective Fc receptor binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1-KLH and GD3-KLH conjugates.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Distribution of adjuvant MF59 and antigen gD2 after intramuscular injection in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Saponins as vaccine adjuvants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215704

Comparison of the effect of different immunological adjuvants on the antibody and T-cell response to immunization with MUC1-KLH and GD3-KLH conjugate cancer vaccines.

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1963

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1963

Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1963

Synthesis of the potent immunostimulatory adjuvant QS-21A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1963

Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1963

Dendritic cells internalize vaccine adjuvant after intramuscular injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1963

The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans

21 January 2018

1 reference

12 December 2020

Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines

1 reference

12 December 2020

Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function

1 reference

12 December 2020

Studies on the cellular site of action of the adjuvant activity of saponin for sheep erythrocytes

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12 December 2020

Adjuvant and haemolytic activities of 47 saponins derived from medicinal and food plants

1 reference

12 December 2020

Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex

1 reference

12 December 2020

QS-21: a water-soluble triterpene glycoside adjuvant

1 reference

12 December 2020

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1H and natural abundance 13C NMR spectroscopy

1 reference

12 December 2020

Assessment of the monoterpene, glycidic and triterpene-moieties’ contributions to the adjuvant function of the CP05 saponin of Calliandra pulcherrima Benth during vaccination against experimental visceral leishmaniasis

1 reference

12 December 2020

Adjuvant activity of QS-21 isomers

1 reference

12 December 2020

4th meeting on Novel Adjuvants Currently in/close to Human Clinical Testing World Health Organization -- organisation Mondiale de la Santé Fondation Mérieux, Annecy, France, 23-25, June 2003

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEM.1963

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Dimensions Publication ID

2 August 2017

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2 August 2017

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