The mucosal immune system: primary target for HIV infection and AIDS. (Q34430862)

2 August 2017

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title

The mucosal immune system: primary target for HIV infection and AIDS. (English)

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2 August 2017

mucosal immune system

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Veazey RS

1

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PubMed ID

11698224

2 August 2017

Marx PA

series ordinal

2

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PubMed ID

11698224

2 August 2017

Lackner AA

series ordinal

3

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2 August 2017

1 November 2001

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2 August 2017

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2 August 2017

22

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2 August 2017

11

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2 August 2017

626-633

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Chemokine control of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

A new classification for HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

The function of simian chemokine receptors in the replication of SIV.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Dynamics of CCR5 expression by CD4(+) T cells in lymphoid tissues during simian immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Indirect mechanisms of HIV pathogenesis: how does HIV kill T cells?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

HIV-1 gp120 accelerates Fas-mediated activation-induced human lamina propria T cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

T cell apoptosis in HIV infection: mechanisms and relevance for AIDS pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Viral dynamics in human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

CD4: CD8 ratio and HIV infection: the "tap-and-drain' hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

AIDS: a disease of impaired Th-cell renewal?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Increased rates of CD4(+) and CD8(+) T lymphocyte turnover in simian immunodeficiency virus-infected macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Rapid turnover of T lymphocytes in SIV-infected rhesus macaques.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4+ T Cell Turnover

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Limited CD4+ T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Enhanced levels of functional HIV-1 co-receptors on human mucosal T cells demonstrated using intestinal biopsy tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Lamina propria lymphocytes, not macrophages, express CCR5 and CXCR4 and are the likely target cell for human immunodeficiency virus type 1 in the intestinal mucosa

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Optimal inhibition of X4 HIV isolates by the CXC chemokine stromal cell-derived factor 1 alpha requires interaction with cell surface heparan sulfate proteoglycans

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Rapid mucosal CD4(+) T-cell depletion and enteropathy in simian immunodeficiency virus-infected rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Loss of mucosal CD4 lymphocytes is an early feature of HIV infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

The extent of early viral replication is a critical determinant of the natural history of simian immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Protective immunity induced by live attenuated simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Reduction of HIV concentration during acute infection: independence from a specific immune response.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Modeling plasma virus concentration during primary HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Enteropathy associated with the acquired immunodeficiency syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Focal enterocyte vacuolization. A new microscopic finding in the acquired immune deficiency wasting syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Ultrastructural features of epithelial cell degeneration in rectal crypts of patients with AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Persistent diarrhoea in Zairian AIDS patients: an endoscopic and histological study

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Intestinal mucosal inflammation associated with human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Gastrointestinal dysfunction and disaccharide intolerance in children infected with human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Impaired Intestinal Function in Symptomatic HIV Infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Intestinal permeability and function in patients infected with human immunodeficiency virus. A comparison with coeliac disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Enteric Immunologic Abnormalities in Human Immunodeficiency Virus Infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Changes in the rate of crypt epithelial cell proliferation and mucosal morphology induced by a T-cell-mediated response in human small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in human small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

The role of lympho-epithelial interactions in the regulation of small intestinal epithelium proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

CCR5 and CXCR4 expression on memory and naive T cells in HIV-1 infection and response to highly active antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902039-7

7 January 2021

10.1016/S1471-4906(01)02039-7

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11698224