Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits (Q34430288)

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English	Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits	scientific article

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scholarly article

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Europe PubMed Central

2 August 2017

Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits (English)

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Europe PubMed Central

2 August 2017

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Eliezer Masliah

8

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Eliezer Masliah

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Europe PubMed Central

2 August 2017

9

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Lennart Mucke

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Europe PubMed Central

2 August 2017

author name string

Julie A Harris

1

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Europe PubMed Central

2 August 2017

Akihiko Koyama

2

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Europe PubMed Central

2 August 2017

Sumihiro Maeda

3

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Europe PubMed Central

2 August 2017

Kaitlyn Ho

4

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Europe PubMed Central

2 August 2017

Nino Devidze

5

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Europe PubMed Central

2 August 2017

Dena B Dubal

6

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2 August 2017

Gui-Qiu Yu

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2 August 2017

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publication date

24 September 2012

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

7

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Europe PubMed Central

2 August 2017

e45881

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Europe PubMed Central

2 August 2017

9

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Europe PubMed Central

2 August 2017

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Creative Commons Attribution 4.0 International

24 September 2012

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April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3454317/fullTextXML

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inferred from PubMed Central ID database lookup

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Trans-synaptic spread of tau pathology in vivo

1 reference

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P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating

1 reference

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1 reference

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Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network

1 reference

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1 reference

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1 reference

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1 reference

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Propagation of tau misfolding from the outside to the inside of a cell.

1 reference

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Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin

1 reference

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Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau

1 reference

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1 reference

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Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

1 reference

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Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).

1 reference

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Tau suppression in a neurodegenerative mouse model improves memory function

1 reference

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Neuroimaging as a marker of the onset and progression of Alzheimer's disease

1 reference

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1 reference

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The medial temporal lobe

1 reference

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1 reference

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Phenotypic correlations in FTDP-17.

1 reference

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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

1 reference

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1 reference

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

6 July 2018

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

6 July 2018

Frequency of stages of Alzheimer-related lesions in different age categories

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

6 July 2018

Neuropathological stageing of Alzheimer-related changes

1 reference

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Early improved and late defective cognition is reflected by dendritic spines in Tau.P301L mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

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Tau transgenic mice as models for cerebrospinal fluid tau biomarkers.

1 reference

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A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

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'Prion-like' propagation of mouse and human tau aggregates in an inducible mouse model of tauopathy

1 reference

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27 October 2018

Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

27 October 2018

CaMKII activation in the entorhinal cortex disrupts previously encoded spatial memory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

27 October 2018

Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

27 October 2018

Spatial memory in the rat requires the dorsolateral band of the entorhinal cortex.

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Spatial disorientation in Alzheimer's disease: the remembrance of things passed.

1 reference

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27 October 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

27 October 2018

Selective deposition of mutant tau in the FTDP-17 brain affected by the P301L mutation.

1 reference

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Pattern of brain destruction in Parkinson's and Alzheimer's diseases.

1 reference

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Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

1 reference

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27 October 2018

Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau.

1 reference

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27 October 2018

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

27 October 2018

Preliminary evidence: decreased GAP-43 message in tangle-bearing neurons relative to adjacent tangle-free neurons in Alzheimer's disease parahippocampal gyrus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3454317

27 October 2018

Fibrillogenic nuclei composed of P301L mutant tau induce elongation of P301L tau but not wild-type tau

1 reference

https://pubmed.ncbi.nlm.nih.gov/23029293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathological process underlying Alzheimer's disease in individuals under thirty

1 reference

https://pubmed.ncbi.nlm.nih.gov/23029293

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0045881

1 reference

Europe PubMed Central

2 August 2017

2012PLoSO...745881H

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1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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